Human Amniotic epithelial cells accelerate diabetic wound healing

TRIM25 promotes Capicua degradation independently of ERK in the absence of ATXN1L

M2 macrophage-derived exosomes promote the c-KIT phenotype of vascular easy muscle cells throughout vascular tissue restore after intravascular stent implantation

Rationale: For intravascular stent implantation to achieve success, the processes of vascular tissue restore and remedy are thought-about to be vital. Nonetheless, the mechanisms underlying the eventual destiny of vascular easy muscle cells (VSMCs) throughout vascular tissue restore stays elusive. On this examine, we hypothesized that M2 macrophage-derived exosomes to mediate cell-to-cell crosstalk and induce dedifferentiation phenotypes in VSMCs.

Strategies: In vivo, 316L naked steel stents (BMS) had been implanted from the left iliac artery into the belly aorta of 12-week-old male Sprague-Dawley (SD) rats for 7 and 28 days. Hematoxylin and eosin (HE) had been used to stain the neointimal lesions. En-face immunofluorescence staining of easy muscle 22 alpha (SM22α) and CD68 confirmed the rat aorta easy muscle cells (RASMCs) and macrophages. Immunohistochemical staining of complete galactose-specific lectin 3 (MAC-2) and complete chitinase 3-like 3 (YM-1) confirmed the overall macrophages and M2 macrophages.

In vitro, exosomes derived from IL-4+IL-13-treated macrophages (M2Es) had been remoted by ultracentrifugation and characterised based mostly on their particular morphology. Ki-67 staining was carried out to evaluate the consequences of the M2Es on the proliferation of RASMCs. An atomic pressure microscope (AFM) was used to detect the stiffness of the VSMCs. GW4869 was used to inhibit exosome launch. RNA-seq was carried out to find out the mRNA profiles of the RASMCs and M2Es-treated RASMCs. Quantitative real-time PCR (qRT-PCR) evaluation was carried out to detect the expression ranges of the mRNAs. Western blotting was used to detect the candidate protein expression ranges. T-5224 was used to inhibit the DNA binding exercise of AP-1 in RASMCs.

Outcomes: M2Es promote c-KIT expression and softening of close by VSMCs, therefore accelerating the vascular tissue restore course of. VSMCs co-cultured in vitro with M2 macrophages introduced an elevated capability for de-differentiation and softening, which was exosome dependent. As well as, the remoted M2Es helped to advertise VSMC dedifferentiation and softening.

Moreover, the M2Es enhanced vascular tissue restore efficiency by upregulation of VSMCs c-KIT expression through activation of the c-Jun/activator protein 1 (AP-1) signaling pathway.

Conclusions: The findings of this examine emphasize the distinguished position of M2Es throughout VSMC dedifferentiation and vascular tissue restore through activation of the c-Jun/AP-1 signaling pathway, which has a profound impression on the therapeutic methods of coronary stenting methods.

ataxin

ataxin

Leukemia - CLL Exosome RNA

P241-CLL - Ask for price

Leukemia - CML Exosome RNA

P241-CML - Ask for price

Leukemia - Hairy Cell Exosome RNA

P241-HC - Ask for price

Leukemia - Multiple Myeloma Exosome RNA

P241-MM - Ask for price

pReceiver-Lv105-AML-1B Plasmid

PVTB00282S 2 ug
EUR 356

Aqueous Mount (Low Viscosity)

AML-10000 10 L
EUR 2083

Psoriasis Exosome

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Bladder Cancer Exosome

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Breast Cancer Exosome

P141-BR - Ask for price

Colorectal Cancer Exosome

P141-CO - Ask for price

Crohn's Disease Exosome

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Kidney Cancer Exosome

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Lung Cancer Exosome

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Liver Cancer Exosome

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Prostate Cancer Exosome

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Rheumatoid Arthritis Exosome

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Psoriasis Exosome RNA

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Exosome precipitation Solution

EPStep 12 ml
EUR 277.5

Lyophilized Exosome Standards

ExoA375 100 μg
EUR 303.5

Lyophilized Exosome Standards

ExoHT29 100 μg
EUR 303.5

Lyophilized Exosome Standards

ExoMCF7 100 μg
EUR 303.5

Lyophilized Exosome Standards

ExoPC3 100 μg
EUR 303.5

Lyophilized Exosome Standards

ExoPLASMA 100 μg
EUR 303.5

Lyophilized Exosome Standards

ExoUrine 100 μg
EUR 303.5

Exosome Isolation kit (for serum & plasma -Exosome-RNA-NGS)

P101NGS - Ask for price

Bovine Leukemia Virus(Leukemia Virus)

QY-E60121 96T
EUR 426

Exosome Component 5 Protein

20-abx260873
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  • EUR 230.00
  • 1 mg
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Exosome Component 7 Protein

20-abx261347
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  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
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Exosome Component 10 Protein

20-abx261805
  • EUR 4365.00
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  • EUR 230.00
  • 1 mg
  • 20 ug
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Exosome Component 4 Protein

20-abx261954
  • EUR 4490.00
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  • EUR 230.00
  • 1 mg
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Exosome Component 9 Protein

20-abx262123
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  • 10 ug
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Exosome Component 8 Protein

20-abx262850
  • EUR 328.00
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  • 10 ug
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Exosome Component 3 Protein

20-abx263422
  • EUR 230.00
  • EUR 1609.00
  • EUR 328.00
  • 1 µg
  • 50 ug
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Exosome Component 1 Protein

20-abx263423
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Exosome-TEM-easy Kit

P130 - Ask for price

Normal human exosome sample

P140 - Ask for price

Diabetes (Type 1) Exosome

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P241-RA - Ask for price

Thyroid Cancer Exosome RNA

P241-TH - Ask for price

Fluorescent Exosome Standard (Urine )

ESF-15 100 µg
EUR 1723
Description: Fluorescent exosomes are labeled with green dye, which offer a stable fluorescent labeling.

EXOCET Exosome Quantitation Kit

EXOCET96A-1 96 reactions
EUR 521

FluoroCet Exosome Quantitation Kit

FCET96A-1 96 reactions
EUR 726

ExoFectin Plasmid DNA-into-Exosome Kit (DNA transfection kit for exosome)

P402 - Ask for price

Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome)

P101EZ - Ask for price

ExoStd? Plasma Fluorescent Exosome Standard

M1073-100
EUR 756

ExoStd? Serum Fluorescent Exosome Standard

M1074-100
EUR 756

ExoStd? Urine Fluorescent Exosome Standard

M1075-100
EUR 756

ExoStd? Saliva Fluorescent Exosome Standard

M1076-100
EUR 756

ExoStd? COLO1 Fluorescent Exosome Standard

M1077-100
EUR 756

ExoStd? MM1 Fluorescent Exosome Standard

M1078-100
EUR 756

ExoStd? BLCL21 Fluorescent Exosome Standard

M1079-100
EUR 756

ExoStd? HCT116 Fluorescent Exosome Standard

M1083-100
EUR 756

ExoStd? PC3 Fluorescent Exosome Standard

M1086-100
EUR 756

ExoStd? DAUD1 Fluorescent Exosome Standard

M1088-100
EUR 756

ExoStd? A549 Fluorescent Exosome Standard

M1089-100
EUR 756

ExoStd? B16F10 Fluorescent Exosome Standard

M1159-100
EUR 773

LiqBiopsy Tumor Exosome RNA Kit

K1254-24
EUR 1110

Exosome Component 1 (EXOSC1) Antibody

20-abx125829
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 2 (EXOSC2) Antibody

20-abx125830
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 3 (EXOSC3) Antibody

20-abx125831
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 1 (EXOSC1) Antibody

20-abx112409
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Exosome Component 10 (EXOSC10) Antibody

20-abx112410
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Exosome Component 2 (EXOSC2) Antibody

20-abx112411
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Exosome Component 3 (EXOSC3) Antibody

20-abx112412
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Exosome Component 4 (EXOSC4) Antibody

20-abx112413
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Exosome Component 5 (EXOSC5) Antibody

20-abx112414
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Exosome Component 8 (EXOSC8) Antibody

20-abx112415
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Exosome Component 7 (EXOSC7) Antibody

20-abx124556
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 4 (EXOSC4) Antibody

20-abx124664
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 8 (EXOSC8) Antibody

20-abx318649
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 3 (EXOSC3) Antibody

20-abx312069
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 1 (EXOSC1) Antibody

abx232898-100ug 100 ug
EUR 481

Exosome Component 10 (EXOSC10) Antibody

abx232899-100ug 100 ug
EUR 551

Exosome Component 10 (EXOSC10) Antibody

abx232900-100ug 100 ug
EUR 509

Exosome Component 2 (EXOSC2) Antibody

abx232901-100ug 100 ug
EUR 481

Exosome Component 2 (EXOSC2) Antibody

abx232902-100ug 100 ug
EUR 551

Exosome Component 3 (EXOSC3) Antibody

abx232903-100ug 100 ug
EUR 481

Exosome Component 4 (EXOSC4) Antibody

abx232904-100ug 100 ug
EUR 481

Exosome Component 5 (EXOSC5) Antibody

abx232905-100ug 100 ug
EUR 509

Exosome Component 7 (EXOSC7) Antibody

abx232906-100ug 100 ug
EUR 551

Exosome Component 8 (EXOSC8) Antibody

abx232907-100ug 100 ug
EUR 481

Exosome Component 9 (EXOSC9) Antibody

abx232908-100ug 100 ug
EUR 551

Exosome Component 2 (EXOSC2) Antibody

20-abx176346
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Exosome Component 2 (EXOSC2) Antibody

20-abx172308
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug

Exosome Component 1 (EXOSC1) Antibody

20-abx301763
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 5 (EXOSC5) Antibody

20-abx302857
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 10 (EXOSC10) Antibody

20-abx334343
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 8 (EXOSC8) Antibody

20-abx003377
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 2 (EXOSC2) Antibody

20-abx003412
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Exosome Component 2 (EXOSC2) Antibody

abx034983-400ul 400 ul
EUR 523

Exosome Component 2 (EXOSC2) Antibody

abx034983-80l 80 µl
EUR 286

Recombinant Human Exosome Component 9

7-05902 2µg Ask for price

Recombinant Human Exosome Component 9

7-05903 10µg Ask for price

Recombinant Human Exosome Component 9

7-05904 1mg Ask for price

Recombinant Human Exosome Component 10

7-05905 5µg Ask for price

Recombinant Human Exosome Component 10

7-05906 20µg Ask for price

Recombinant Human Exosome Component 10

7-05907 1mg Ask for price

Exosome Component 8 (EXOSC8) Antibody

abx031706-400ul 400 ul
EUR 523

Exosome Component 8 (EXOSC8) Antibody

abx031706-80l 80 µl
EUR 286

Exosome Component 4 (EXOSC4) Antibody

abx029390-400ul 400 ul
EUR 523

Exosome Component 4 (EXOSC4) Antibody

abx029390-80l 80 µl
EUR 286

Exosome Component 1 (EXOSC1) Antibody

abx030303-400ul 400 ul
EUR 523

 

Exosomes derived from human amniotic epithelial cells speed up diabetic wound therapeutic through PI3K-AKT-mTOR-mediated promotion in angiogenesis and fibroblast operate

Background: Diabetic wounds are one of the vital widespread and severe problems of diabetes mellitus, characterised by the dysfunction of wound-healing-related cells in amount and high quality. Our earlier research revealed that human amniotic epithelial cells (hAECs) might promote diabetic wound therapeutic by paracrine motion.

 

Apparently, quite a few research demonstrated that exosomes derived from stem cells are the vital paracrine autos for stem cell remedy. Nonetheless, whether or not exosomes derived from hAECs (hAECs-Exos) mediate the consequences of hAECs on diabetic wound therapeutic stays unclear. This examine aimed to research the organic results of hAECs-Exos on diabetic wound therapeutic and preliminarily elucidate the underlying mechanism.

 

Strategies: hAECs-Exos had been remoted by ultracentrifugation and recognized by transmission electron microscopy, dynamic mild scattering and circulation cytometry. A collection of in vitro useful analyses had been carried out to evaluate the regulatory results of hAECs-Exos on human fibroblasts (HFBs) and human umbilical vein endothelial cells (HUVECs) in a high-glycemic microenvironment. Excessive-throughput sequencing and bioinformatics analyses had been carried out to invest the associated mechanisms of actions of hAECs-Exos on HFBs and HUVECs. Subsequently, the position of the candidate signaling pathway of hAECs-Exos in regulating the operate of HUVECs and HFBs, in addition to in diabetic wound therapeutic, was assessed.

 

Outcomes: hAECs-Exos introduced a cup- or sphere-shaped morphology with a imply diameter of 105.89 ± 10.36 nm, had been constructive for CD63 and TSG101 and may very well be internalized by HFBs and HUVECs. After that, hAECs-Exos not solely considerably promoted the proliferation and migration of HFBs, but in addition facilitated the angiogenic exercise of HUVECs in vitro.

 

Excessive-throughput sequencing revealed enriched miRNAs of hAECs-Exos concerned in wound therapeutic. Kyoto Encyclopedia of Genes and Genomes and Gene Ontology analyses have proven that the goal genes of the highest 15 miRNAs had been extremely enriched within the PI3K-AKT pathway. Additional useful research demonstrated that the PI3K-AKT-mTOR pathway was mandatory for the induced organic results of hAECs-Exos on HFBs and HUVECs, in addition to on wound therapeutic, in diabetic mice.

 

Conclusions: Our findings demonstrated that hAECs-Exos signify a promising, novel technique for diabetic wound therapeutic by selling angiogenesis and fibroblast operate through activation of the PI3K-AKT-mTOR pathway.

 

Leukemia - AML Exosome RNA

P241-AML - Ask for price

Leukemia - CLL Exosome RNA

P241-CLL - Ask for price

General Carboxymethyl Lysine (CML) ELISA Kit

RD-CML-Ge-48Tests 48 Tests
EUR 586

General Carboxymethyl Lysine (CML) ELISA Kit

RD-CML-Ge-96Tests 96 Tests
EUR 816

General Carboxymethyl Lysine (CML) ELISA Kit

RDR-CML-Ge-48Tests 48 Tests
EUR 613

General Carboxymethyl Lysine (CML) ELISA Kit

RDR-CML-Ge-96Tests 96 Tests
EUR 854

Leukemia - Hairy Cell Exosome RNA

P241-HC - Ask for price

Leukemia - Multiple Myeloma Exosome RNA

P241-MM - Ask for price

CML-BSA Control

STA-314 100 µg
EUR 322
Description:
  • CML-BSA may be used as a positive control. 100 µg.
  • Provided at 1 mg/mL in 1X PBS

CML ELISA KIT|Human

EF007324 96 Tests
EUR 689

Sheep CML ELISA Kit

ESC0780 96Tests
EUR 521

Mouse CML ELISA Kit

EMC0780 96Tests
EUR 521

Monkey CML ELISA Kit

EMKC0780 96Tests
EUR 521

Porcine CML ELISA Kit

EPC0780 96Tests
EUR 521

Rat CML ELISA Kit

ERC0780 96Tests
EUR 521

Rabbit CML ELISA Kit

ERTC0780 96Tests
EUR 521

Anserini CML ELISA Kit

EAC0780 96Tests
EUR 521

Goat CML ELISA Kit

EGTC0780 96Tests
EUR 521

Canine CML ELISA Kit

ECC0780 96Tests
EUR 521

Chicken CML ELISA Kit

ECKC0780 96Tests
EUR 521

Human CML ELISA Kit

EHC0780 96Tests
EUR 521

Bovine CML ELISA Kit

EBC0780 96Tests
EUR 521

Carboxymethyl Lysine (CML) Antibody

abx023261-1mg 1 mg
EUR 1080

Psoriasis Exosome

P141-PS - Ask for price

Carboxymethyl Lysine (CML) ELISA Kit

E4634-100
EUR 729

Carboxymethyl Lysine (CML) ELISA Kit

20-abx150327
  • EUR 7645.00
  • EUR 4074.00
  • EUR 942.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Guinea Pig CML ELISA Kit

EGC0780 96Tests
EUR 521

Carboxymethyl Lysine (CML) CLIA Kit

20-abx490445
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

K-562 Cell Slide (Human (53yrs, Female) bone marrow, chronic myelogenous leukemia (CML)) (5 slides/pk)

HCLS-17004 1 pk
EUR 250

Bladder Cancer Exosome

P141-BL - Ask for price

Breast Cancer Exosome

P141-BR - Ask for price

Colorectal Cancer Exosome

P141-CO - Ask for price

Crohn's Disease Exosome

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P141-RA - Ask for price

Thyroid Cancer Exosome

P141-TH - Ask for price

Psoriasis Exosome RNA

P241-PS - Ask for price

Exosome precipitation Solution

EPStep 12 ml
EUR 277.5

Lyophilized Exosome Standards

ExoA375 100 μg
EUR 303.5

Lyophilized Exosome Standards

ExoHT29 100 μg
EUR 303.5

Lyophilized Exosome Standards

ExoMCF7 100 μg
EUR 303.5

Lyophilized Exosome Standards

ExoPC3 100 μg
EUR 303.5

Lyophilized Exosome Standards

ExoPLASMA 100 μg
EUR 303.5

Lyophilized Exosome Standards

ExoUrine 100 μg
EUR 303.5

General Carboxymethyl Lysine (CML) ELISA Kit

CEB977Ge-10x96wellstestplate 10x96-wells test plate
EUR 5438.36
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Carboxymethyl Lysine (CML) in serum, plasma and other biological fluids.

General Carboxymethyl Lysine (CML) ELISA Kit

CEB977Ge-1x48wellstestplate 1x48-wells test plate
EUR 535.51
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Carboxymethyl Lysine (CML) in serum, plasma and other biological fluids.

General Carboxymethyl Lysine (CML) ELISA Kit

CEB977Ge-1x96wellstestplate 1x96-wells test plate
EUR 722.16
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Carboxymethyl Lysine (CML) in serum, plasma and other biological fluids.

General Carboxymethyl Lysine (CML) ELISA Kit

CEB977Ge-5x96wellstestplate 5x96-wells test plate
EUR 2949.72
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Carboxymethyl Lysine (CML) in serum, plasma and other biological fluids.

General Carboxymethyl Lysine (CML) ELISA Kit

4-CEB977Ge
  • EUR 5489.00
  • EUR 2900.00
  • EUR 723.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of General Carboxymethyl Lysine (CML) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Carboxymethyl lysine, CML ELISA Kit

CSB-E12798h-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human Carboxymethyl lysine, CML in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Carboxymethyl lysine, CML ELISA Kit

1-CSB-E12798h
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Carboxymethyl lysine, CML in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

N(6)-Carboxymethyllysine (CML) ELISA Kit

abx575945-96tests 96 tests
EUR 668

Human Carboxymethyl lysine(CML)ELISA Kit

GA-E1430HM-48T 48T
EUR 289

Human Carboxymethyl lysine(CML)ELISA Kit

GA-E1430HM-96T 96T
EUR 466

Human Carboxymethyl lysine,CML ELISA Kit

201-12-1414 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

General Carboxymethyl Lysine ELISA Kit (CML)

RK00635 96 Tests
EUR 521

Human CML(Carboxymethyl Lysine) ELISA Kit

EH4116 96T
EUR 524.1
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 9.4 ng/ml

Human Carboxymethyl lysine(CML)ELISA Kit

QY-E01351 96T
EUR 361

Exosome Isolation kit (for serum & plasma -Exosome-RNA-NGS)

P101NGS - Ask for price

Bovine Leukemia Virus(Leukemia Virus)

QY-E60121 96T
EUR 426

General N(6)- Carboxymethyllysine, CML ELISA KIT

ELI-06348Ge 96 Tests
EUR 886

Bovine N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019b 96 Tests
EUR 928

Chicken N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019c 96 Tests
EUR 928

Canine N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019d 96 Tests
EUR 928

General N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019Ge 96 Tests
EUR 886

Human N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019h 96 Tests
EUR 824

Mouse N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019m 96 Tests
EUR 865

Porcine N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019p 96 Tests
EUR 928

Rat N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019r 96 Tests
EUR 886

Rabbit N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019Rb 96 Tests
EUR 928

General CML/ N(6)-Carboxymethyllysine ELISA Kit

E0014Ge 1 Kit
EUR 717

Goat Anti-N-epsilon-CML Polyclonal Antibody

STA-013 100 µg
EUR 508
Description: Goat Anti-CML Polyclonal Antibody is Affinity purified and suitable for Western blot or ELISA. Suitable for use with any species. 100 µg.

Rabbit Anti-N-epsilon-CML Polyclonal Antibody

STA-014 100 µg
EUR 508
Description: Rabbit Anti-CML Polyclonal Antibody is Affinity purified and suitable for Western blot or ELISA. Suitable for use with any species. 100 µg.

ELISA kit for General CML (Carboxymethyl Lysine)

ELK7896 1 plate of 96 wells
EUR 372
Description: A competitive Inhibition ELISA kit for detection of Carboxymethyl Lysine from General in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Fluorescent Exosome Standard (Urine )

ESF-15 100 µg
EUR 1723
Description: Fluorescent exosomes are labeled with green dye, which offer a stable fluorescent labeling.

Exosome Component 5 Protein

20-abx260873
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 25 ug
  • 5 ug

Exosome Component 7 Protein

20-abx261347
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

Exosome Component 10 Protein

20-abx261805
  • EUR 4365.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

Exosome Component 4 Protein

20-abx261954
  • EUR 4490.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

Exosome Component 9 Protein

20-abx262123
  • EUR 328.00
  • EUR 5089.00
  • EUR 230.00
  • 10 ug
  • 1 mg
  • 2 µg

Exosome Component 8 Protein

20-abx262850
  • EUR 328.00
  • EUR 6397.00
  • EUR 230.00
  • 10 ug
  • 1 mg
  • 2 µg

Exosome Component 3 Protein

20-abx263422
  • EUR 230.00
  • EUR 1609.00
  • EUR 328.00
  • 1 µg
  • 50 ug
  • 5 ug

Exosome Component 1 Protein

20-abx263423
  • EUR 1609.00
  • EUR 328.00
  • EUR 230.00
  • 100 ug
  • 10 ug
  • 2 µg

Exosome-TEM-easy Kit

P130 - Ask for price

Normal human exosome sample

P140 - Ask for price

Diabetes (Type 1) Exosome

P141-DB1 - Ask for price

Diabetes (Type 2) Exosome

P141-DB2 - Ask for price

Melanoma (skin cancer) Exosome

P141-MN - Ask for price

Non-Hodgkin lymphoma Exosome

P141-NH - Ask for price

Systemic Lupus Erythematosus Exosome

P141-SL - Ask for price

Uterine Cervical Cancer Exosome

P141-UC - Ask for price

Uterine Corpus Cancer Exosome

P141-UT - Ask for price

Normal human exosome RNA

P240 - Ask for price

Bladder Cancer Exosome RNA

P241-BL - Ask for price

Breast Cancer Exosome RNA

P241-BR - Ask for price

Colorectal Cancer Exosome RNA

P241-CO - Ask for price

Crohn's Disease Exosome RNA

P241-CR - Ask for price

Kidney Cancer Exosome RNA

P241-KN - Ask for price

Lung Cancer Exosome RNA

P241-LG - Ask for price

Liver Cancer Exosome RNA

P241-LV - Ask for price

Nasopharyngeal Cancer Exosome RNA

P241-NA - Ask for price

Prostate Cancer Exosome RNA

P241-PR - Ask for price

Rheumatoid Arthritis Exosome RNA

P241-RA - Ask for price

Thyroid Cancer Exosome RNA

P241-TH - Ask for price

EXOCET Exosome Quantitation Kit

EXOCET96A-1 96 reactions
EUR 521

FluoroCet Exosome Quantitation Kit

FCET96A-1 96 reactions
EUR 726

ExoFectin Plasmid DNA-into-Exosome Kit (DNA transfection kit for exosome)

P402 - Ask for price

CML ELISA Kit| Rat Carboxymethyl Lysine ELISA Kit

EF018173 96 Tests
EUR 689

CML ELISA Kit| Mouse Carboxymethyl Lysine ELISA Kit

EF014018 96 Tests
EUR 689

OxiSelect N-epsilon-(Carboxymethyl) Lysine (CML) Immunoblot Kit

STA-313 10 blots
EUR 531
Description: Advanced glycation end products (AGE) are formed during the Maillard reaction where reducing carbohydrates react with lysine side chains and N-terminal amino groups of various macromolecules, particularly proteins. The advanced glycation end products can adversely affect the fuction of these macromolecules. One of the most prevalent AGE products, N-epsilon-(Carboxymethyl) Lysine, has been implicated in oxidative stress and vascular damage. The OxiSelect N-epsilon-(Carboxymethyl) Lysine Immunoblot kit specifically detects CML formation in protein samples.

OxiSelect N?-(carboxymethyl) lysine (CML) Competitive ELISA Kit

STA-816 96 assays
EUR 798
Description: Advanced glycation end products (AGE) are formed during the Maillard reaction where reducing carbohydrates react with lysine side chains and N-terminal amino groups of various macromolecules, particularly proteins. The advanced glycation end products can adversely affect the fuction of these macromolecules. One of the most prevalent AGE products, N-epsilon-(Carboxymethyl) Lysine, has been implicated in oxidative stress and vascular damage. The OxiSelect N-epsilon-(Carboxymethyl) Lysine Competitive ELISA kit specifically detects CML formation with a high level of sensitivity. This is a Competitive ELISA Kit in which the plate is coated with a CML conjugate.  Standards and unknown samples are added to the plate, followed by incubation with the primary antibody. The CML in the unknown samples and the CML attached to the plate compete for the primary antibody. Higher CML content in unknown samples results in more binding of the antibody to the sample, and thus less antibody binds to the plate. Since the antibody bound to the sample is washed away, higher CML content in samples correlates with a lower signal.

OxiSelect N?-(carboxymethyl) lysine (CML) Competitive ELISA Kit

STA-816-5 5 x 96 assays
EUR 3240
Description: Advanced glycation end products (AGE) are formed during the Maillard reaction where reducing carbohydrates react with lysine side chains and N-terminal amino groups of various macromolecules, particularly proteins. The advanced glycation end products can adversely affect the fuction of these macromolecules. One of the most prevalent AGE products, N-epsilon-(Carboxymethyl) Lysine, has been implicated in oxidative stress and vascular damage. The OxiSelect N-epsilon-(Carboxymethyl) Lysine Competitive ELISA kit specifically detects CML formation with a high level of sensitivity. This is a Competitive ELISA Kit in which the plate is coated with a CML conjugate.  Standards and unknown samples are added to the plate, followed by incubation with the primary antibody. The CML in the unknown samples and the CML attached to the plate compete for the primary antibody. Higher CML content in unknown samples results in more binding of the antibody to the sample, and thus less antibody binds to the plate. Since the antibody bound to the sample is washed away, higher CML content in samples correlates with a lower signal.

ELISA kit for Rat N(6)-Carboxymethyllysine (CML)

KTE101082-48T 48T
EUR 354
Description: Quantitative sandwich ELISA for measuring Rat N(6)-Carboxymethyllysine (CML) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat N(6)-Carboxymethyllysine (CML)

KTE101082-5platesof96wells 5 plates of 96 wells
EUR 2252
Description: Quantitative sandwich ELISA for measuring Rat N(6)-Carboxymethyllysine (CML) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat N(6)-Carboxymethyllysine (CML)

KTE101082-96T 96T
EUR 572
Description: Quantitative sandwich ELISA for measuring Rat N(6)-Carboxymethyllysine (CML) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Anti CML Monoclonal Antibody (Clone No. CMS-10)

KH011
EUR 714
Description: The Anti CML Monoclonal Antibody (Clone No. CMS-10) is available in Europe and for worldwide shipping via Gentaur.

Anti CML Monoclonal Antibody (Clone No. NF-1G)

KH024
EUR 714
Description: The Anti CML Monoclonal Antibody (Clone No. NF-1G) is available in Europe and for worldwide shipping via Gentaur.

Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome)

P101EZ - Ask for price

ExoStd? Plasma Fluorescent Exosome Standard

M1073-100
EUR 756

ExoStd? Serum Fluorescent Exosome Standard

M1074-100
EUR 756

ExoStd? Urine Fluorescent Exosome Standard

M1075-100
EUR 756

ExoStd? Saliva Fluorescent Exosome Standard

M1076-100
EUR 756

ExoStd? COLO1 Fluorescent Exosome Standard

M1077-100
EUR 756

ExoStd? MM1 Fluorescent Exosome Standard

M1078-100
EUR 756

ExoStd? BLCL21 Fluorescent Exosome Standard

M1079-100
EUR 756

ExoStd? HCT116 Fluorescent Exosome Standard

M1083-100
EUR 756

ExoStd? PC3 Fluorescent Exosome Standard

M1086-100
EUR 756

ExoStd? DAUD1 Fluorescent Exosome Standard

M1088-100
EUR 756

ExoStd? A549 Fluorescent Exosome Standard

M1089-100
EUR 756

ExoStd? B16F10 Fluorescent Exosome Standard

M1159-100
EUR 773

LiqBiopsy Tumor Exosome RNA Kit

K1254-24
EUR 1110

Lyophilized Exosome Standard (Human Plasma)

ESL-25 30 µgx2 vials
EUR 1337
Description: Lyophilized exosomes can be used as control standards for FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from biological samples.

Lyophilized Exosome Standard (Human Saliva)

ESL-27 30 µgx6 vials
EUR 3023
Description: Lyophilized exosomes can be used as control standards for FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from biological samples.

Lyophilized Exosome Standard (Human Urine)

ESL-29 30 µgx2 vials
EUR 1350
Description: Lyophilized exosomes can be used as control standards for FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from biological samples.

Lyophilized Exosome Standard (Human Serum)

ESL-32 30 µgx2 vials
EUR 1350
Description: Lyophilized exosomes can be used as control standards for FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from biological samples.

Exosome Component 1 (EXOSC1) Antibody

20-abx301763
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 5 (EXOSC5) Antibody

20-abx302857
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 1 (EXOSC1) Antibody

20-abx125829
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 2 (EXOSC2) Antibody

20-abx125830
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 3 (EXOSC3) Antibody

20-abx125831
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 1 (EXOSC1) Antibody

20-abx112409
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Exosome Component 10 (EXOSC10) Antibody

20-abx112410
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Exosome Component 2 (EXOSC2) Antibody

20-abx112411
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Exosome Component 3 (EXOSC3) Antibody

20-abx112412
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Exosome Component 4 (EXOSC4) Antibody

20-abx112413
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Exosome Component 5 (EXOSC5) Antibody

20-abx112414
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Exosome Component 8 (EXOSC8) Antibody

20-abx112415
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Exosome Component 7 (EXOSC7) Antibody

20-abx124556
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 4 (EXOSC4) Antibody

20-abx124664
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 2 (EXOSC2) Antibody

abx034983-400ul 400 ul
EUR 523

Exosome Component 2 (EXOSC2) Antibody

abx034983-80l 80 µl
EUR 286

Exosome Component 8 (EXOSC8) Antibody

20-abx003377
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 2 (EXOSC2) Antibody

20-abx003412
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Exosome Component 4 (EXOSC4) Antibody

abx029390-400ul 400 ul
EUR 523

Exosome Component 4 (EXOSC4) Antibody

abx029390-80l 80 µl
EUR 286

Exosome Component 1 (EXOSC1) Antibody

abx030303-400ul 400 ul
EUR 523

Exosome Component 1 (EXOSC1) Antibody

abx030303-80l 80 µl
EUR 286

Exosome Component 8 (EXOSC8) Antibody

abx031706-400ul 400 ul
EUR 523

Exosome Component 8 (EXOSC8) Antibody

abx031706-80l 80 µl
EUR 286

Recombinant Human Exosome Component 9

7-05902 2µg Ask for price

Recombinant Human Exosome Component 9

7-05903 10µg Ask for price

Recombinant Human Exosome Component 9

7-05904 1mg Ask for price

Recombinant Human Exosome Component 10

7-05905 5µg Ask for price

Recombinant Human Exosome Component 10

7-05906 20µg Ask for price

Recombinant Human Exosome Component 10

7-05907 1mg Ask for price

Exosome Component 2 (EXOSC2) Antibody

20-abx172308
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug

Exosome Component 8 (EXOSC8) Antibody

20-abx318649
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 3 (EXOSC3) Antibody

20-abx312069
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 1 (EXOSC1) Antibody

abx232898-100ug 100 ug
EUR 481

Exosome Component 10 (EXOSC10) Antibody

abx232899-100ug 100 ug
EUR 551

Exosome Component 10 (EXOSC10) Antibody

abx232900-100ug 100 ug
EUR 509

Exosome Component 2 (EXOSC2) Antibody

abx232901-100ug 100 ug
EUR 481

Exosome Component 2 (EXOSC2) Antibody

abx232902-100ug 100 ug
EUR 551

Exosome Component 3 (EXOSC3) Antibody

abx232903-100ug 100 ug
EUR 481

Exosome Component 4 (EXOSC4) Antibody

abx232904-100ug 100 ug
EUR 481

Exosome Component 5 (EXOSC5) Antibody

abx232905-100ug 100 ug
EUR 509

Exosome Component 7 (EXOSC7) Antibody

abx232906-100ug 100 ug
EUR 551

Exosome Component 8 (EXOSC8) Antibody

abx232907-100ug 100 ug
EUR 481

Exosome Component 9 (EXOSC9) Antibody

abx232908-100ug 100 ug
EUR 551

Exosome Component 2 (EXOSC2) Antibody

20-abx176346
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Exosome Isolation kit (for urine)

P120 - Ask for price

Exosome Isolation kit (for urine)

P120L - Ask for price

Exosome Isolation kit (for urine)

P120S - Ask for price

Diabetes (Type 1) Exosome RNA

P241-DB1 - Ask for price

Diabetes (Type 2) Exosome RNA

P241-DB2 - Ask for price

Melanoma (skin cancer) Exosome RNA

P241-MN - Ask for price

 

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