Human Amniotic epithelial cells accelerate diabetic wound healing

TRIM25 promotes Capicua degradation independently of ERK in the absence of ATXN1L

M2 macrophage-derived exosomes promote the c-KIT phenotype of vascular easy muscle cells throughout vascular tissue restore after intravascular stent implantation

Rationale: For intravascular stent implantation to achieve success, the processes of vascular tissue restore and remedy are thought-about to be vital. Nonetheless, the mechanisms underlying the eventual destiny of vascular easy muscle cells (VSMCs) throughout vascular tissue restore stays elusive. On this examine, we hypothesized that M2 macrophage-derived exosomes to mediate cell-to-cell crosstalk and induce dedifferentiation phenotypes in VSMCs.

Strategies: In vivo, 316L naked steel stents (BMS) had been implanted from the left iliac artery into the belly aorta of 12-week-old male Sprague-Dawley (SD) rats for 7 and 28 days. Hematoxylin and eosin (HE) had been used to stain the neointimal lesions. En-face immunofluorescence staining of easy muscle 22 alpha (SM22α) and CD68 confirmed the rat aorta easy muscle cells (RASMCs) and macrophages. Immunohistochemical staining of complete galactose-specific lectin 3 (MAC-2) and complete chitinase 3-like 3 (YM-1) confirmed the overall macrophages and M2 macrophages.

In vitro, exosomes derived from IL-4+IL-13-treated macrophages (M2Es) had been remoted by ultracentrifugation and characterised based mostly on their particular morphology. Ki-67 staining was carried out to evaluate the consequences of the M2Es on the proliferation of RASMCs. An atomic pressure microscope (AFM) was used to detect the stiffness of the VSMCs. GW4869 was used to inhibit exosome launch. RNA-seq was carried out to find out the mRNA profiles of the RASMCs and M2Es-treated RASMCs. Quantitative real-time PCR (qRT-PCR) evaluation was carried out to detect the expression ranges of the mRNAs. Western blotting was used to detect the candidate protein expression ranges. T-5224 was used to inhibit the DNA binding exercise of AP-1 in RASMCs.

Outcomes: M2Es promote c-KIT expression and softening of close by VSMCs, therefore accelerating the vascular tissue restore course of. VSMCs co-cultured in vitro with M2 macrophages introduced an elevated capability for de-differentiation and softening, which was exosome dependent. As well as, the remoted M2Es helped to advertise VSMC dedifferentiation and softening.

Moreover, the M2Es enhanced vascular tissue restore efficiency by upregulation of VSMCs c-KIT expression through activation of the c-Jun/activator protein 1 (AP-1) signaling pathway.

Conclusions: The findings of this examine emphasize the distinguished position of M2Es throughout VSMC dedifferentiation and vascular tissue restore through activation of the c-Jun/AP-1 signaling pathway, which has a profound impression on the therapeutic methods of coronary stenting methods.

ataxin

ataxin

Leukemia - CLL Exosome RNA

P241-CLL - Ask for price

Leukemia - CML Exosome RNA

P241-CML - Ask for price

Leukemia - Hairy Cell Exosome RNA

P241-HC - Ask for price

Leukemia - Multiple Myeloma Exosome RNA

P241-MM - Ask for price

pReceiver-Lv105-AML-1B Plasmid

PVTB00282S 2 ug
EUR 427.2

ReadiCleave™ AML Cy5 NHS ester

7000 1 mg
EUR 446

ReadiCleave™ XFD532 AML-NHS ester

7001 1 mg
EUR 412

ReadiCleave™ ROXtra AML-NHS ester

7002 1 mg
EUR 412

ReadiCleave™ FITC AML-NHS ester

7004 1 mg
EUR 412

ReadiCleave® XFD488 AML-NHS ester

7008 1 mg
EUR 403

ReadiCleave® XFD546 AML-NHS ester

7009 1 mg
EUR 403

Aqueous Mount (Low Viscosity)

AML-10000 10 L
EUR 2499.6

Psoriasis Exosome

P141-PS - Ask for price

ReadiCleave™ iFluor 700 AML-NHS ester

7003 1 mg
EUR 412

ReadiCleave™ iFluor 488 AML-NHS ester

7005 1 mg
EUR 412

ReadiCleave™ iFluor 546 AML-NHS ester

7006 1 mg
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ReadiCleave™ iFluor 594 AML-NHS ester

7007 1 mg
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Exosome precipitation Solution

EPStep 12 ml
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Bladder Cancer Exosome

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Breast Cancer Exosome

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Colorectal Cancer Exosome

P141-CO - Ask for price

Crohn's Disease Exosome

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Lyophilized Exosome Standards

ExoA375 100 μg
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Lyophilized Exosome Standards

ExoHT29 100 μg
EUR 364.2

Lyophilized Exosome Standards

ExoMCF7 100 μg
EUR 364.2

Lyophilized Exosome Standards

ExoPC3 100 μg
EUR 364.2

Lyophilized Exosome Standards

ExoPLASMA 100 μg
EUR 364.2

Lyophilized Exosome Standards

ExoUrine 100 μg
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Psoriasis Exosome RNA

P241-PS - Ask for price

Exosome Isolation kit (for serum & plasma -Exosome-RNA-NGS)

P101NGS - Ask for price

Bovine Leukemia Virus(Leukemia Virus)

QY-E60121 96T
EUR 511.2

Exosome Component 9 Peptide

46-967P 0.1 mg
EUR 405.6
Description: (CT) PMSCL1 Peptide

Exosome Component 3 Protein

20-abx263422
  • EUR 276.00
  • EUR 1930.80
  • EUR 393.60
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Exosome Component 1 Protein

20-abx263423
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Exosome Component 5 Protein

20-abx260873
  • EUR 4101.60
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  • 1 mg
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Exosome Component 7 Protein

20-abx261347
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  • 1 mg
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Exosome Component 10 Protein

20-abx261805
  • EUR 5238.00
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  • 1 mg
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Exosome Component 4 Protein

20-abx261954
  • EUR 5388.00
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  • 1 mg
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Exosome Component 9 Protein

20-abx262123
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Exosome Component 8 Protein

20-abx262850
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Exosome-TEM-easy Kit

P130 - Ask for price

Diabetes (Type 1) Exosome

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EXOCET Exosome Quantitation Kit

EXOCET96A-1 96 reactions
EUR 625.2

Fluorescent Exosome Standard (Urine )

ESF-15 100 µg
EUR 2067.6
Description: Fluorescent exosomes are labeled with green dye, which offer a stable fluorescent labeling.

FluoroCet Exosome Quantitation Kit

FCET96A-1 96 reactions
EUR 871.2

Normal human exosome RNA

P240 - Ask for price

Bladder Cancer Exosome RNA

P241-BL - Ask for price

Breast Cancer Exosome RNA

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Thyroid Cancer Exosome RNA

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Leukemia-Spleen Tissue Slide (Lymphoma/Leukemia)

11-601-10um 10 um
EUR 241.8

Leukemia-Spleen Tissue Slide (Lymphoma/Leukemia)

11-601-4um 4 um
EUR 216.6

ExoFectin Plasmid DNA-into-Exosome Kit (DNA transfection kit for exosome)

P402 - Ask for price

Lymphoma/Leukemia-Spleen Tissue Slide (Lymphoma/Leukemia)

11-606-10um 10 um
EUR 241.8

Lymphoma/Leukemia-Spleen Tissue Slide (Lymphoma/Leukemia)

11-606-4um 4 um
EUR 216.6

Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome)

P101EZ - Ask for price

Recombinant Human Exosome Component 9

7-05902 2µg Ask for price

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7-05903 10µg Ask for price

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7-05904 1mg Ask for price

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7-05905 5µg Ask for price

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7-05906 20µg Ask for price

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7-05907 1mg Ask for price

Exosome Component 8 (EXOSC8) Antibody

20-abx003377
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
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Exosome Component 2 (EXOSC2) Antibody

20-abx003412
  • EUR 493.20
  • EUR 710.40
  • 100 ul
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Exosome Component 7 (EXOSC7) Antibody

20-abx124556
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
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Exosome Component 4 (EXOSC4) Antibody

20-abx124664
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
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Exosome Component 1 (EXOSC1) Antibody

20-abx125829
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
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Exosome Component 2 (EXOSC2) Antibody

20-abx125830
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
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Exosome Component 3 (EXOSC3) Antibody

20-abx125831
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
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Exosome Component 1 (EXOSC1) Antibody

20-abx112409
  • EUR 878.40
  • EUR 477.60
  • 150 ul
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Exosome Component 10 (EXOSC10) Antibody

20-abx112410
  • EUR 878.40
  • EUR 477.60
  • 150 ul
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Exosome Component 2 (EXOSC2) Antibody

20-abx112411
  • EUR 878.40
  • EUR 477.60
  • 150 ul
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Exosome Component 3 (EXOSC3) Antibody

20-abx112412
  • EUR 878.40
  • EUR 477.60
  • 150 ul
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Exosome Component 4 (EXOSC4) Antibody

20-abx112413
  • EUR 878.40
  • EUR 477.60
  • 150 ul
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Exosome Component 5 (EXOSC5) Antibody

20-abx112414
  • EUR 878.40
  • EUR 477.60
  • 150 ul
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Exosome Component 8 (EXOSC8) Antibody

20-abx112415
  • EUR 878.40
  • EUR 477.60
  • 150 ul
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Exosome Component 2 (EXOSC2) Antibody

abx034983-400ul 400 ul
EUR 627.6

Exosome Component 2 (EXOSC2) Antibody

abx034983-80l 80 µl
EUR 343.2

Exosome Component 4 (EXOSC4) Antibody

abx029390-400ul 400 ul
EUR 627.6

Exosome Component 4 (EXOSC4) Antibody

abx029390-80l 80 µl
EUR 343.2

Exosome Component 1 (EXOSC1) Antibody

abx030303-400ul 400 ul
EUR 627.6

Exosome Component 1 (EXOSC1) Antibody

abx030303-80l 80 µl
EUR 343.2

Exosome Component 8 (EXOSC8) Antibody

abx031706-400ul 400 ul
EUR 627.6

Exosome Component 8 (EXOSC8) Antibody

abx031706-80l 80 µl
EUR 343.2

Exosome Component 10 (EXOSC10) Antibody

20-abx334343
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 1 (EXOSC1) Antibody

20-abx301763
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 5 (EXOSC5) Antibody

20-abx302857
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 8 (EXOSC8) Antibody

20-abx318649
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 3 (EXOSC3) Antibody

20-abx312069
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 1 (EXOSC1) Antibody

abx232898-100ug 100 ug
EUR 577.2

Exosome Component 10 (EXOSC10) Antibody

abx232899-100ug 100 ug
EUR 661.2

Exosome Component 10 (EXOSC10) Antibody

abx232900-100ug 100 ug
EUR 610.8

Exosome Component 2 (EXOSC2) Antibody

abx232901-100ug 100 ug
EUR 577.2

Exosome Component 2 (EXOSC2) Antibody

abx232902-100ug 100 ug
EUR 661.2

Exosome Component 3 (EXOSC3) Antibody

abx232903-100ug 100 ug
EUR 577.2

Exosome Component 4 (EXOSC4) Antibody

abx232904-100ug 100 ug
EUR 577.2

Exosome Component 5 (EXOSC5) Antibody

abx232905-100ug 100 ug
EUR 610.8

Exosome Component 7 (EXOSC7) Antibody

abx232906-100ug 100 ug
EUR 661.2

Exosome Component 8 (EXOSC8) Antibody

abx232907-100ug 100 ug
EUR 577.2

Exosome Component 9 (EXOSC9) Antibody

abx232908-100ug 100 ug
EUR 661.2

 

Exosomes derived from human amniotic epithelial cells speed up diabetic wound therapeutic through PI3K-AKT-mTOR-mediated promotion in angiogenesis and fibroblast operate

Background: Diabetic wounds are one of the vital widespread and severe problems of diabetes mellitus, characterised by the dysfunction of wound-healing-related cells in amount and high quality. Our earlier research revealed that human amniotic epithelial cells (hAECs) might promote diabetic wound therapeutic by paracrine motion.

 

Apparently, quite a few research demonstrated that exosomes derived from stem cells are the vital paracrine autos for stem cell remedy. Nonetheless, whether or not exosomes derived from hAECs (hAECs-Exos) mediate the consequences of hAECs on diabetic wound therapeutic stays unclear. This examine aimed to research the organic results of hAECs-Exos on diabetic wound therapeutic and preliminarily elucidate the underlying mechanism.

 

Strategies: hAECs-Exos had been remoted by ultracentrifugation and recognized by transmission electron microscopy, dynamic mild scattering and circulation cytometry. A collection of in vitro useful analyses had been carried out to evaluate the regulatory results of hAECs-Exos on human fibroblasts (HFBs) and human umbilical vein endothelial cells (HUVECs) in a high-glycemic microenvironment. Excessive-throughput sequencing and bioinformatics analyses had been carried out to invest the associated mechanisms of actions of hAECs-Exos on HFBs and HUVECs. Subsequently, the position of the candidate signaling pathway of hAECs-Exos in regulating the operate of HUVECs and HFBs, in addition to in diabetic wound therapeutic, was assessed.

 

Outcomes: hAECs-Exos introduced a cup- or sphere-shaped morphology with a imply diameter of 105.89 ± 10.36 nm, had been constructive for CD63 and TSG101 and may very well be internalized by HFBs and HUVECs. After that, hAECs-Exos not solely considerably promoted the proliferation and migration of HFBs, but in addition facilitated the angiogenic exercise of HUVECs in vitro.

 

Excessive-throughput sequencing revealed enriched miRNAs of hAECs-Exos concerned in wound therapeutic. Kyoto Encyclopedia of Genes and Genomes and Gene Ontology analyses have proven that the goal genes of the highest 15 miRNAs had been extremely enriched within the PI3K-AKT pathway. Additional useful research demonstrated that the PI3K-AKT-mTOR pathway was mandatory for the induced organic results of hAECs-Exos on HFBs and HUVECs, in addition to on wound therapeutic, in diabetic mice.

 

Conclusions: Our findings demonstrated that hAECs-Exos signify a promising, novel technique for diabetic wound therapeutic by selling angiogenesis and fibroblast operate through activation of the PI3K-AKT-mTOR pathway.

 

Leukemia - AML Exosome RNA

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General Carboxymethyl Lysine (CML) ELISA Kit

RD-CML-Ge-48Tests 48 Tests
EUR 703.2

General Carboxymethyl Lysine (CML) ELISA Kit

RD-CML-Ge-96Tests 96 Tests
EUR 979.2

General Carboxymethyl Lysine (CML) ELISA Kit

RDR-CML-Ge-48Tests 48 Tests
EUR 735.6

General Carboxymethyl Lysine (CML) ELISA Kit

RDR-CML-Ge-96Tests 96 Tests
EUR 1024.8

Leukemia - Hairy Cell Exosome RNA

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Leukemia - Multiple Myeloma Exosome RNA

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CML-BSA Control

STA-314 100 µg
EUR 386.4
Description:
  • CML-BSA may be used as a positive control. 100 µg.
  • Provided at 1 mg/mL in 1X PBS

Carboxymethyl Lysine (CML) Antibody

abx023261-1mg 1 mg
EUR 1296

Porcine CML ELISA Kit

EPC0780 96Tests
EUR 625.2

Rabbit CML ELISA Kit

ERTC0780 96Tests
EUR 625.2

Rat CML ELISA Kit

ERC0780 96Tests
EUR 625.2

Mouse CML ELISA Kit

EMC0780 96Tests
EUR 625.2

Monkey CML ELISA Kit

EMKC0780 96Tests
EUR 625.2

Human CML ELISA Kit

EHC0780 96Tests
EUR 625.2

CML ELISA KIT|Human

EF007324 96 Tests
EUR 826.8

Goat CML ELISA Kit

EGTC0780 96Tests
EUR 625.2

Canine CML ELISA Kit

ECC0780 96Tests
EUR 625.2

Chicken CML ELISA Kit

ECKC0780 96Tests
EUR 625.2

Anserini CML ELISA Kit

EAC0780 96Tests
EUR 625.2

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EBC0780 96Tests
EUR 625.2

Sheep CML ELISA Kit

ESC0780 96Tests
EUR 625.2

Psoriasis Exosome

P141-PS - Ask for price

Carboxymethyl Lysine (CML) ELISA Kit

20-abx150327
  • EUR 9174.00
  • EUR 4888.80
  • EUR 1130.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Carboxymethyl Lysine (CML) CLIA Kit

20-abx490445
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Guinea Pig CML ELISA Kit

EGC0780 96Tests
EUR 625.2

Carboxymethyl Lysine (CML) ELISA Kit

E4634-100
EUR 874.8

K-562 Cell Slide (Human (53yrs, Female) bone marrow, chronic myelogenous leukemia (CML)) (5 slides/pk)

HCLS-17004 1 pk
EUR 300

Exosome precipitation Solution

EPStep 12 ml
EUR 333

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Lyophilized Exosome Standards

ExoA375 100 μg
EUR 364.2

Lyophilized Exosome Standards

ExoHT29 100 μg
EUR 364.2

Lyophilized Exosome Standards

ExoMCF7 100 μg
EUR 364.2

Lyophilized Exosome Standards

ExoPC3 100 μg
EUR 364.2

Lyophilized Exosome Standards

ExoPLASMA 100 μg
EUR 364.2

Lyophilized Exosome Standards

ExoUrine 100 μg
EUR 364.2

Psoriasis Exosome RNA

P241-PS - Ask for price

N(6)-Carboxymethyllysine (CML) ELISA Kit

abx575945-96tests 96 tests
EUR 801.6

Human Carboxymethyl lysine,CML ELISA Kit

201-12-1414 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Carboxymethyl lysine, CML ELISA Kit

CSB-E12798h-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Carboxymethyl lysine, CML in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Carboxymethyl lysine, CML ELISA Kit

1-CSB-E12798h
  • EUR 1080.00
  • EUR 6571.20
  • EUR 3480.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Carboxymethyl lysine, CML in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

General Carboxymethyl Lysine (CML) ELISA Kit

CEB977Ge-10x96wellstestplate 10x96-wells test plate
EUR 6526.03
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Carboxymethyl Lysine (CML) in serum, plasma and other biological fluids.

General Carboxymethyl Lysine (CML) ELISA Kit

CEB977Ge-1x48wellstestplate 1x48-wells test plate
EUR 642.61
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Carboxymethyl Lysine (CML) in serum, plasma and other biological fluids.

General Carboxymethyl Lysine (CML) ELISA Kit

CEB977Ge-1x96wellstestplate 1x96-wells test plate
EUR 866.59
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Carboxymethyl Lysine (CML) in serum, plasma and other biological fluids.

General Carboxymethyl Lysine (CML) ELISA Kit

CEB977Ge-5x96wellstestplate 5x96-wells test plate
EUR 3539.66
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Carboxymethyl Lysine (CML) in serum, plasma and other biological fluids.

General Carboxymethyl Lysine (CML) ELISA Kit

4-CEB977Ge
  • EUR 6586.80
  • EUR 3480.00
  • EUR 867.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of General Carboxymethyl Lysine (CML) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

Human CML(Carboxymethyl Lysine) ELISA Kit

EH4116 96T
EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 9.4 ng/ml

Human Carboxymethyl lysine(CML)ELISA Kit

GA-E1430HM-48T 48T
EUR 346.8

Human Carboxymethyl lysine(CML)ELISA Kit

GA-E1430HM-96T 96T
EUR 559.2

General Carboxymethyl Lysine ELISA Kit (CML)

RK00635 96 Tests
EUR 625.2

Human Carboxymethyl lysine(CML)ELISA Kit

QY-E01351 96T
EUR 433.2

Exosome Isolation kit (for serum & plasma -Exosome-RNA-NGS)

P101NGS - Ask for price

Bovine Leukemia Virus(Leukemia Virus)

QY-E60121 96T
EUR 511.2

Exosome Component 9 Peptide

46-967P 0.1 mg
EUR 405.6
Description: (CT) PMSCL1 Peptide

Exosome Component 3 Protein

20-abx263422
  • EUR 276.00
  • EUR 1930.80
  • EUR 393.60
  • 1 µg
  • 50 ug
  • 5 ug

Exosome Component 1 Protein

20-abx263423
  • EUR 1930.80
  • EUR 393.60
  • EUR 276.00
  • 100 ug
  • 10 ug
  • 2 µg

Exosome Component 5 Protein

20-abx260873
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

Exosome Component 7 Protein

20-abx261347
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Exosome Component 10 Protein

20-abx261805
  • EUR 5238.00
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Exosome Component 4 Protein

20-abx261954
  • EUR 5388.00
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Exosome Component 9 Protein

20-abx262123
  • EUR 393.60
  • EUR 6106.80
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Exosome Component 8 Protein

20-abx262850
  • EUR 393.60
  • EUR 7676.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Exosome-TEM-easy Kit

P130 - Ask for price

Diabetes (Type 1) Exosome

P141-DB1 - Ask for price

Diabetes (Type 2) Exosome

P141-DB2 - Ask for price

Melanoma (skin cancer) Exosome

P141-MN - Ask for price

Non-Hodgkin lymphoma Exosome

P141-NH - Ask for price

Systemic Lupus Erythematosus Exosome

P141-SL - Ask for price

Uterine Cervical Cancer Exosome

P141-UC - Ask for price

Uterine Corpus Cancer Exosome

P141-UT - Ask for price

EXOCET Exosome Quantitation Kit

EXOCET96A-1 96 reactions
EUR 625.2

Fluorescent Exosome Standard (Urine )

ESF-15 100 µg
EUR 2067.6
Description: Fluorescent exosomes are labeled with green dye, which offer a stable fluorescent labeling.

FluoroCet Exosome Quantitation Kit

FCET96A-1 96 reactions
EUR 871.2

Normal human exosome RNA

P240 - Ask for price

Bladder Cancer Exosome RNA

P241-BL - Ask for price

Breast Cancer Exosome RNA

P241-BR - Ask for price

Colorectal Cancer Exosome RNA

P241-CO - Ask for price

Crohn's Disease Exosome RNA

P241-CR - Ask for price

Kidney Cancer Exosome RNA

P241-KN - Ask for price

Lung Cancer Exosome RNA

P241-LG - Ask for price

Liver Cancer Exosome RNA

P241-LV - Ask for price

Nasopharyngeal Cancer Exosome RNA

P241-NA - Ask for price

Prostate Cancer Exosome RNA

P241-PR - Ask for price

Rheumatoid Arthritis Exosome RNA

P241-RA - Ask for price

Thyroid Cancer Exosome RNA

P241-TH - Ask for price

Bovine N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019b 96 Tests
EUR 1113.6

Chicken N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019c 96 Tests
EUR 1113.6

Canine N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019d 96 Tests
EUR 1113.6

General N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019Ge 96 Tests
EUR 1063.2

Human N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019h 96 Tests
EUR 988.8

Mouse N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019m 96 Tests
EUR 1038

Porcine N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019p 96 Tests
EUR 1113.6

Rat N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019r 96 Tests
EUR 1063.2

Rabbit N(6)- Carboxymethyllysine, CML ELISA Kit

CELI-66019Rb 96 Tests
EUR 1113.6

General CML/ N(6)-Carboxymethyllysine ELISA Kit

E0014Ge 1 Kit
EUR 860.4

ELISA kit for General CML (Carboxymethyl Lysine)

ELK7896 1 plate of 96 wells
EUR 446.4
Description: A competitive Inhibition ELISA kit for detection of Carboxymethyl Lysine from General in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

General N(6)- Carboxymethyllysine, CML ELISA KIT

ELI-06348Ge 96 Tests
EUR 1063.2

Goat Anti-N-epsilon-CML Polyclonal Antibody

STA-013 100 µg
EUR 609.6
Description: Goat Anti-CML Polyclonal Antibody is Affinity purified and suitable for Western blot or ELISA. Suitable for use with any species. 100 µg.

Rabbit Anti-N-epsilon-CML Polyclonal Antibody

STA-014 100 µg
EUR 609.6
Description: Rabbit Anti-CML Polyclonal Antibody is Affinity purified and suitable for Western blot or ELISA. Suitable for use with any species. 100 µg.

Leukemia-Spleen Tissue Slide (Lymphoma/Leukemia)

11-601-10um 10 um
EUR 241.8

Leukemia-Spleen Tissue Slide (Lymphoma/Leukemia)

11-601-4um 4 um
EUR 216.6

ExoFectin Plasmid DNA-into-Exosome Kit (DNA transfection kit for exosome)

P402 - Ask for price

Lymphoma/Leukemia-Spleen Tissue Slide (Lymphoma/Leukemia)

11-606-10um 10 um
EUR 241.8

Lymphoma/Leukemia-Spleen Tissue Slide (Lymphoma/Leukemia)

11-606-4um 4 um
EUR 216.6

CML ELISA Kit| Mouse Carboxymethyl Lysine ELISA Kit

EF014018 96 Tests
EUR 826.8

CML ELISA Kit| Rat Carboxymethyl Lysine ELISA Kit

EF018173 96 Tests
EUR 826.8

Anti CML Monoclonal Antibody (Clone No. CMS-10)

KH011
EUR 856.8
Description: The Anti CML Monoclonal Antibody (Clone No. CMS-10) is available in Europe and for worldwide shipping via Gentaur.

Anti CML Monoclonal Antibody (Clone No. NF-1G)

KH024
EUR 856.8
Description: The Anti CML Monoclonal Antibody (Clone No. NF-1G) is available in Europe and for worldwide shipping via Gentaur.

ELISA kit for Rat N(6)-Carboxymethyllysine (CML)

KTE101082-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Rat N(6)-Carboxymethyllysine (CML) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat N(6)-Carboxymethyllysine (CML)

KTE101082-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Rat N(6)-Carboxymethyllysine (CML) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat N(6)-Carboxymethyllysine (CML)

KTE101082-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Rat N(6)-Carboxymethyllysine (CML) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

OxiSelect N-epsilon-(Carboxymethyl) Lysine (CML) Immunoblot Kit

STA-313 10 blots
EUR 637.2
Description: Advanced glycation end products (AGE) are formed during the Maillard reaction where reducing carbohydrates react with lysine side chains and N-terminal amino groups of various macromolecules, particularly proteins. The advanced glycation end products can adversely affect the fuction of these macromolecules. One of the most prevalent AGE products, N-epsilon-(Carboxymethyl) Lysine, has been implicated in oxidative stress and vascular damage. The OxiSelect N-epsilon-(Carboxymethyl) Lysine Immunoblot kit specifically detects CML formation in protein samples.

OxiSelect N?-(carboxymethyl) lysine (CML) Competitive ELISA Kit

STA-816 96 assays
EUR 957.6
Description: Advanced glycation end products (AGE) are formed during the Maillard reaction where reducing carbohydrates react with lysine side chains and N-terminal amino groups of various macromolecules, particularly proteins. The advanced glycation end products can adversely affect the fuction of these macromolecules. One of the most prevalent AGE products, N-epsilon-(Carboxymethyl) Lysine, has been implicated in oxidative stress and vascular damage. The OxiSelect N-epsilon-(Carboxymethyl) Lysine Competitive ELISA kit specifically detects CML formation with a high level of sensitivity. This is a Competitive ELISA Kit in which the plate is coated with a CML conjugate.  Standards and unknown samples are added to the plate, followed by incubation with the primary antibody. The CML in the unknown samples and the CML attached to the plate compete for the primary antibody. Higher CML content in unknown samples results in more binding of the antibody to the sample, and thus less antibody binds to the plate. Since the antibody bound to the sample is washed away, higher CML content in samples correlates with a lower signal.

OxiSelect N?-(carboxymethyl) lysine (CML) Competitive ELISA Kit

STA-816-5 5 x 96 assays
EUR 3888
Description: Advanced glycation end products (AGE) are formed during the Maillard reaction where reducing carbohydrates react with lysine side chains and N-terminal amino groups of various macromolecules, particularly proteins. The advanced glycation end products can adversely affect the fuction of these macromolecules. One of the most prevalent AGE products, N-epsilon-(Carboxymethyl) Lysine, has been implicated in oxidative stress and vascular damage. The OxiSelect N-epsilon-(Carboxymethyl) Lysine Competitive ELISA kit specifically detects CML formation with a high level of sensitivity. This is a Competitive ELISA Kit in which the plate is coated with a CML conjugate.  Standards and unknown samples are added to the plate, followed by incubation with the primary antibody. The CML in the unknown samples and the CML attached to the plate compete for the primary antibody. Higher CML content in unknown samples results in more binding of the antibody to the sample, and thus less antibody binds to the plate. Since the antibody bound to the sample is washed away, higher CML content in samples correlates with a lower signal.

Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome)

P101EZ - Ask for price

Recombinant Human Exosome Component 9

7-05902 2µg Ask for price

Recombinant Human Exosome Component 9

7-05903 10µg Ask for price

Recombinant Human Exosome Component 9

7-05904 1mg Ask for price

Recombinant Human Exosome Component 10

7-05905 5µg Ask for price

Recombinant Human Exosome Component 10

7-05906 20µg Ask for price

Recombinant Human Exosome Component 10

7-05907 1mg Ask for price

Exosome Component 8 (EXOSC8) Antibody

20-abx003377
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 2 (EXOSC2) Antibody

20-abx003412
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Exosome Component 7 (EXOSC7) Antibody

20-abx124556
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 4 (EXOSC4) Antibody

20-abx124664
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 1 (EXOSC1) Antibody

20-abx125829
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 2 (EXOSC2) Antibody

20-abx125830
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 3 (EXOSC3) Antibody

20-abx125831
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Exosome Component 1 (EXOSC1) Antibody

20-abx112409
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Exosome Component 10 (EXOSC10) Antibody

20-abx112410
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Exosome Component 2 (EXOSC2) Antibody

20-abx112411
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Exosome Component 3 (EXOSC3) Antibody

20-abx112412
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Exosome Component 4 (EXOSC4) Antibody

20-abx112413
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Exosome Component 5 (EXOSC5) Antibody

20-abx112414
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Exosome Component 8 (EXOSC8) Antibody

20-abx112415
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Exosome Component 2 (EXOSC2) Antibody

abx034983-400ul 400 ul
EUR 627.6

Exosome Component 2 (EXOSC2) Antibody

abx034983-80l 80 µl
EUR 343.2

Exosome Component 4 (EXOSC4) Antibody

abx029390-400ul 400 ul
EUR 627.6

Exosome Component 4 (EXOSC4) Antibody

abx029390-80l 80 µl
EUR 343.2

Exosome Component 1 (EXOSC1) Antibody

abx030303-400ul 400 ul
EUR 627.6

Exosome Component 1 (EXOSC1) Antibody

abx030303-80l 80 µl
EUR 343.2

Exosome Component 8 (EXOSC8) Antibody

abx031706-400ul 400 ul
EUR 627.6

Exosome Component 8 (EXOSC8) Antibody

abx031706-80l 80 µl
EUR 343.2

Exosome Component 10 (EXOSC10) Antibody

20-abx334343
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 1 (EXOSC1) Antibody

20-abx301763
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 5 (EXOSC5) Antibody

20-abx302857
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 8 (EXOSC8) Antibody

20-abx318649
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 3 (EXOSC3) Antibody

20-abx312069
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 1 (EXOSC1) Antibody

abx232898-100ug 100 ug
EUR 577.2

Exosome Component 10 (EXOSC10) Antibody

abx232899-100ug 100 ug
EUR 661.2

Exosome Component 10 (EXOSC10) Antibody

abx232900-100ug 100 ug
EUR 610.8

Exosome Component 2 (EXOSC2) Antibody

abx232901-100ug 100 ug
EUR 577.2

Exosome Component 2 (EXOSC2) Antibody

abx232902-100ug 100 ug
EUR 661.2

Exosome Component 3 (EXOSC3) Antibody

abx232903-100ug 100 ug
EUR 577.2

Exosome Component 4 (EXOSC4) Antibody

abx232904-100ug 100 ug
EUR 577.2

Exosome Component 5 (EXOSC5) Antibody

abx232905-100ug 100 ug
EUR 610.8

Exosome Component 7 (EXOSC7) Antibody

abx232906-100ug 100 ug
EUR 661.2

Exosome Component 8 (EXOSC8) Antibody

abx232907-100ug 100 ug
EUR 577.2

Exosome Component 9 (EXOSC9) Antibody

abx232908-100ug 100 ug
EUR 661.2

Exosome Component 2 (EXOSC2) Antibody

20-abx172308
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

Exosome Component 2 (EXOSC2) Antibody

20-abx176346
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Exosome precipitation from Plasma + Thrombin

EPStep-T 5 ml
EUR 403.2

ExoStd? Plasma Fluorescent Exosome Standard

M1073-100
EUR 907.2

ExoStd? Serum Fluorescent Exosome Standard

M1074-100
EUR 907.2

ExoStd? Urine Fluorescent Exosome Standard

M1075-100
EUR 907.2

ExoStd? Saliva Fluorescent Exosome Standard

M1076-100
EUR 907.2

ExoStd? COLO1 Fluorescent Exosome Standard

M1077-100
EUR 907.2

ExoStd? MM1 Fluorescent Exosome Standard

M1078-100
EUR 907.2

ExoStd? BLCL21 Fluorescent Exosome Standard

M1079-100
EUR 907.2

ExoStd? HCT116 Fluorescent Exosome Standard

M1083-100
EUR 907.2

ExoStd? PC3 Fluorescent Exosome Standard

M1086-100
EUR 907.2

ExoStd? DAUD1 Fluorescent Exosome Standard

M1088-100
EUR 907.2

ExoStd? A549 Fluorescent Exosome Standard

M1089-100
EUR 907.2

ExoStd? B16F10 Fluorescent Exosome Standard

M1159-100
EUR 927.6

Exosome Isolation kit (for urine)

P120L - Ask for price

Exosome Isolation kit (for urine)

P120S - Ask for price

LiqBiopsy Tumor Exosome RNA Kit

K1254-24
EUR 1332

Exo-Fect Exosome Transfection Kit

EXFT10A-1 10 reactions
EUR 351.6

Exo-Fect Exosome Transfection Kit

EXFT20A-1 20 reactions
EUR 586.8

 

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