M2 macrophage-derived exosomes promote the c-KIT phenotype of vascular easy muscle cells throughout vascular tissue restore after intravascular stent implantation
Rationale: For intravascular stent implantation to achieve success, the processes of vascular tissue restore and remedy are thought-about to be vital. Nonetheless, the mechanisms underlying the eventual destiny of vascular easy muscle cells (VSMCs) throughout vascular tissue restore stays elusive. On this examine, we hypothesized that M2 macrophage-derived exosomes to mediate cell-to-cell crosstalk and induce dedifferentiation phenotypes in VSMCs.
Strategies: In vivo, 316L naked steel stents (BMS) had been implanted from the left iliac artery into the belly aorta of 12-week-old male Sprague-Dawley (SD) rats for 7 and 28 days. Hematoxylin and eosin (HE) had been used to stain the neointimal lesions. En-face immunofluorescence staining of easy muscle 22 alpha (SM22α) and CD68 confirmed the rat aorta easy muscle cells (RASMCs) and macrophages. Immunohistochemical staining of complete galactose-specific lectin 3 (MAC-2) and complete chitinase 3-like 3 (YM-1) confirmed the overall macrophages and M2 macrophages.
In vitro, exosomes derived from IL-4+IL-13-treated macrophages (M2Es) had been remoted by ultracentrifugation and characterised based mostly on their particular morphology. Ki-67 staining was carried out to evaluate the consequences of the M2Es on the proliferation of RASMCs. An atomic pressure microscope (AFM) was used to detect the stiffness of the VSMCs. GW4869 was used to inhibit exosome launch. RNA-seq was carried out to find out the mRNA profiles of the RASMCs and M2Es-treated RASMCs. Quantitative real-time PCR (qRT-PCR) evaluation was carried out to detect the expression ranges of the mRNAs. Western blotting was used to detect the candidate protein expression ranges. T-5224 was used to inhibit the DNA binding exercise of AP-1 in RASMCs.
Outcomes: M2Es promote c-KIT expression and softening of close by VSMCs, therefore accelerating the vascular tissue restore course of. VSMCs co-cultured in vitro with M2 macrophages introduced an elevated capability for de-differentiation and softening, which was exosome dependent. As well as, the remoted M2Es helped to advertise VSMC dedifferentiation and softening.
Moreover, the M2Es enhanced vascular tissue restore efficiency by upregulation of VSMCs c-KIT expression through activation of the c-Jun/activator protein 1 (AP-1) signaling pathway.
Conclusions: The findings of this examine emphasize the distinguished position of M2Es throughout VSMC dedifferentiation and vascular tissue restore through activation of the c-Jun/AP-1 signaling pathway, which has a profound impression on the therapeutic methods of coronary stenting methods.
ataxin
Leukemia - Hairy Cell Exosome |
|||
| P141-HC | 101Bio | - | Ask for price |
Leukemia - Multiple Myeloma Exosome |
|||
| P141-MM | 101Bio | - | Ask for price |
Leukemia - Hairy Cell Exosome RNA |
|||
| P241-HC | 101Bio | - | Ask for price |
Leukemia - Multiple Myeloma Exosome RNA |
|||
| P241-MM | 101Bio | - | Ask for price |
Exosome derived from human pleural effusion, leukemia chronic myelogenous (K-562 cell line) |
|||
| Exo-CH11 | Creative BioMart | Each | EUR 1147.5 |
|
Description: Exosome |
|||
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) |
|||
| MBS643680-01mL | MyBiosource | 0.1mL | EUR 675 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) |
|||
| MBS643680-5x01mL | MyBiosource | 5x0.1mL | EUR 2880 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) |
|||
| MBS6004590-005mg | MyBiosource | 0.05(mg | EUR 630 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) |
|||
| MBS6004590-5x005mg | MyBiosource | 5x0.05mg | EUR 2680 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) |
|||
| MBS649502-01mg | MyBiosource | 0.1mg | EUR 630 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) |
|||
| MBS649502-5x01mg | MyBiosource | 5x0.1mg | EUR 2680 |
Fluorescent labeled exosome derived from human pleural effusion, leukemia chronic myelogenous (K-562 cell line) |
|||
| Exo-F488-K-562 | Creative BioMart | Each | EUR 1593.75 |
|
Description: Exosome |
|||
Fluorescent labeled exosome derived from human pleural effusion, leukemia chronic myelogenous (K-562 cell line) |
|||
| Exo-F665-K-562 | Creative BioMart | Each | EUR 1249.5 |
|
Description: Exosome |
|||
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (PE) |
|||
| MBS6157714-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (PE) |
|||
| MBS6157714-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (HRP) |
|||
| MBS6155997-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (HRP) |
|||
| MBS6155997-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (AP) |
|||
| MBS6131199-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (AP) |
|||
| MBS6131199-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (AP) |
|||
| MBS6134785-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (AP) |
|||
| MBS6134785-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) APC |
|||
| MBS6140088-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) APC |
|||
| MBS6140088-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) APC |
|||
| MBS6136502-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) APC |
|||
| MBS6136502-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (FITC) |
|||
| MBS6147108-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (FITC) |
|||
| MBS6147108-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (HRP) |
|||
| MBS6152411-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (HRP) |
|||
| MBS6152411-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (FITC) |
|||
| MBS6150694-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (FITC) |
|||
| MBS6150694-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (PE) |
|||
| MBS6161300-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (PE) |
|||
| MBS6161300-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (Biotin) |
|||
| MBS6141805-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (Biotin) |
|||
| MBS6141805-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (Biotin) |
|||
| MBS6145391-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (Biotin) |
|||
| MBS6145391-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 750) |
|||
| MBS6236817-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 750) |
|||
| MBS6236817-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 405) |
|||
| MBS6194117-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 405) |
|||
| MBS6194117-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 650) |
|||
| MBS6226142-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 650) |
|||
| MBS6226142-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 650) |
|||
| MBS6222087-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 650) |
|||
| MBS6222087-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 490) |
|||
| MBS6200737-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 490) |
|||
| MBS6200737-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 490) |
|||
| MBS6204792-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 490) |
|||
| MBS6204792-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 405) |
|||
| MBS6190062-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 405) |
|||
| MBS6190062-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 550) |
|||
| MBS6211412-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 550) |
|||
| MBS6211412-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 550) |
|||
| MBS6215467-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 550) |
|||
| MBS6215467-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 750) |
|||
| MBS6232762-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 750) |
|||
| MBS6232762-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
Purified Exosomes: HTK562 Human Chronic Myelogenous Leukemia Cell Line |
|||
| EXOP-415A-1 | SBI | 50 µg | EUR 514 |
Psoriasis Exosome |
|||
| P141-PS | 101Bio | - | Ask for price |
Exosome Isolation kit (for serum & plasma -Exosome-RNA-NGS) |
|||
| P101NGS | 101Bio | - | Ask for price |
Lung Cancer Exosome |
|||
| P141-LG | 101Bio | - | Ask for price |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) |
|||
| MBS6002539-02mL | MyBiosource | 0.2(mL | EUR 695 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) |
|||
| MBS6002539-5x02mL | MyBiosource | 5x0.2mL | EUR 2975 |
Liver Cancer Exosome |
|||
| P141-LV | 101Bio | - | Ask for price |
Breast Cancer Exosome |
|||
| P141-BR | 101Bio | - | Ask for price |
Crohn's Disease Exosome |
|||
| P141-CR | 101Bio | - | Ask for price |
Kidney Cancer Exosome |
|||
| P141-KN | 101Bio | - | Ask for price |
Psoriasis Exosome RNA |
|||
| P241-PS | 101Bio | - | Ask for price |
Exosome Isolation Kit |
|||
| EIK01 | Creative BioMart | 2T | EUR 800 |
|
Description: Chromatography Reagents |
|||
Exosome Isolation Kit |
|||
| E601E001 | EnoGene | 20 tests | EUR 2500 |
Exosome Isolation Kit |
|||
| MBS8579443-20Tests | MyBiosource | 20Tests | EUR 2625 |
Exosome Isolation Kit |
|||
| MBS8579443-5x20Tests | MyBiosource | 5x20Tests | EUR 12240 |
Bladder Cancer Exosome |
|||
| P141-BL | 101Bio | - | Ask for price |
Thyroid Cancer Exosome |
|||
| P141-TH | 101Bio | - | Ask for price |
Prostate Cancer Exosome |
|||
| P141-PR | 101Bio | - | Ask for price |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (AP) |
|||
| MBS6297130-02mL | MyBiosource | 0.2mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (AP) |
|||
| MBS6297130-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (PE) |
|||
| MBS6297140-02mL | MyBiosource | 0.2mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (PE) |
|||
| MBS6297140-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (APC) |
|||
| MBS6297131-02mL | MyBiosource | 0.2mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (APC) |
|||
| MBS6297131-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (FITC) |
|||
| MBS6297133-02mL | MyBiosource | 0.2mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (FITC) |
|||
| MBS6297133-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
Bovine Leukemia Virus(Leukemia Virus) |
|||
| QY-E60121 | Qayee Biotechnology | 96T | EUR 511.2 |
Colorectal Cancer Exosome |
|||
| P141-CO | 101Bio | - | Ask for price |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (Biotin) |
|||
| MBS6297132-02mL | MyBiosource | 0.2mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (Biotin) |
|||
| MBS6297132-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
Rat Exosome ELISA Kit |
|||
| MBS3808774-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Rat Exosome ELISA Kit |
|||
| MBS3808774-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Rat Exosome ELISA Kit |
|||
| MBS3808774-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Rat Exosome ELISA Kit |
|||
| MBS3808774-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome) |
|||
| P101EZ | 101Bio | - | Ask for price |
Rheumatoid Arthritis Exosome |
|||
| P141-RA | 101Bio | - | Ask for price |
Exosome fluorescent staining |
|||
| S104 | 101Bio | - | EUR 800 |
Lung Cancer Exosome RNA |
|||
| P241-LG | 101Bio | - | Ask for price |
Nasopharyngeal Cancer Exosome |
|||
| P141-NA | 101Bio | - | Ask for price |
Lyophilized Exosome Standards |
|||
| ExoA375 | ImmunoStep | 100 μg | EUR 214.5 |
|
Description: Lyophilized Exosomes from A375 a human breast cancer cell line |
|||
Lyophilized Exosome Standards |
|||
| ExoHT29 | ImmunoStep | 100 μg | EUR 214.5 |
|
Description: Lyophilized Exosomes from HT-29, a human colon cancer cell line |
|||
Lyophilized Exosome Standards |
|||
| ExoMCF7 | ImmunoStep | 100 μg | EUR 214.5 |
|
Description: Lyophilized Exosomes from MCF-7, a human breast cancer cell line |
|||
Lyophilized Exosome Standards |
|||
| ExoPC3 | ImmunoStep | 100 μg | EUR 214.5 |
|
Description: Exosomes from PC-3, a human metastatic prostate cancer cell line |
|||
Lyophilized Exosome Standards |
|||
| ExoPLASMA | ImmunoStep | 100 μg | EUR 364.2 |
Lyophilized Exosome Standards |
|||
| ExoUrine | ImmunoStep | 100 μg | EUR 364.2 |
Diabetes (Type 1) Exosome |
|||
| P141-DB1 | 101Bio | - | Ask for price |
Diabetes (Type 2) Exosome |
|||
| P141-DB2 | 101Bio | - | Ask for price |
Liver Cancer Exosome RNA |
|||
| P241-LV | 101Bio | - | Ask for price |
Normal human exosome RNA |
|||
| P240 | 101Bio | - | EUR 1499 |
Exosome-TEM-easy Kit |
|||
| P130 | 101Bio | 10 rxn | EUR 489 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 405) |
|||
| MBS6297135-01mL | MyBiosource | 0.1mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 405) |
|||
| MBS6297135-5x01mL | MyBiosource | 5x0.1mL | EUR 4250 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 490) |
|||
| MBS6297136-01mL | MyBiosource | 0.1mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 490) |
|||
| MBS6297136-5x01mL | MyBiosource | 5x0.1mL | EUR 4250 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 550) |
|||
| MBS6297137-01mL | MyBiosource | 0.1mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 550) |
|||
| MBS6297137-5x01mL | MyBiosource | 5x0.1mL | EUR 4250 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 650) |
|||
| MBS6297138-01mL | MyBiosource | 0.1mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 650) |
|||
| MBS6297138-5x01mL | MyBiosource | 5x0.1mL | EUR 4250 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 750) |
|||
| MBS6297139-01mL | MyBiosource | 0.1mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 750) |
|||
| MBS6297139-5x01mL | MyBiosource | 5x0.1mL | EUR 4250 |
Exosome Precipitation Solution |
|||
| EPStep | ImmunoStep | 12 ml | EUR 242 |
|
Description: Exosome Precipitation Solution - 12ml |
|||
Breast Cancer Exosome RNA |
|||
| P241-BR | 101Bio | - | Ask for price |
Crohn's Disease Exosome RNA |
|||
| P241-CR | 101Bio | - | Ask for price |
Exosomes derived from human amniotic epithelial cells speed up diabetic wound therapeutic through PI3K-AKT-mTOR-mediated promotion in angiogenesis and fibroblast operate
Background: Diabetic wounds are one of the vital widespread and severe problems of diabetes mellitus, characterised by the dysfunction of wound-healing-related cells in amount and high quality. Our earlier research revealed that human amniotic epithelial cells (hAECs) might promote diabetic wound therapeutic by paracrine motion.
Apparently, quite a few research demonstrated that exosomes derived from stem cells are the vital paracrine autos for stem cell remedy. Nonetheless, whether or not exosomes derived from hAECs (hAECs-Exos) mediate the consequences of hAECs on diabetic wound therapeutic stays unclear. This examine aimed to research the organic results of hAECs-Exos on diabetic wound therapeutic and preliminarily elucidate the underlying mechanism.
Strategies: hAECs-Exos had been remoted by ultracentrifugation and recognized by transmission electron microscopy, dynamic mild scattering and circulation cytometry. A collection of in vitro useful analyses had been carried out to evaluate the regulatory results of hAECs-Exos on human fibroblasts (HFBs) and human umbilical vein endothelial cells (HUVECs) in a high-glycemic microenvironment. Excessive-throughput sequencing and bioinformatics analyses had been carried out to invest the associated mechanisms of actions of hAECs-Exos on HFBs and HUVECs. Subsequently, the position of the candidate signaling pathway of hAECs-Exos in regulating the operate of HUVECs and HFBs, in addition to in diabetic wound therapeutic, was assessed.
Outcomes: hAECs-Exos introduced a cup- or sphere-shaped morphology with a imply diameter of 105.89 ± 10.36 nm, had been constructive for CD63 and TSG101 and may very well be internalized by HFBs and HUVECs. After that, hAECs-Exos not solely considerably promoted the proliferation and migration of HFBs, but in addition facilitated the angiogenic exercise of HUVECs in vitro.
Excessive-throughput sequencing revealed enriched miRNAs of hAECs-Exos concerned in wound therapeutic. Kyoto Encyclopedia of Genes and Genomes and Gene Ontology analyses have proven that the goal genes of the highest 15 miRNAs had been extremely enriched within the PI3K-AKT pathway. Additional useful research demonstrated that the PI3K-AKT-mTOR pathway was mandatory for the induced organic results of hAECs-Exos on HFBs and HUVECs, in addition to on wound therapeutic, in diabetic mice.
Conclusions: Our findings demonstrated that hAECs-Exos signify a promising, novel technique for diabetic wound therapeutic by selling angiogenesis and fibroblast operate through activation of the PI3K-AKT-mTOR pathway.
Leukemia - Hairy Cell Exosome RNA |
|||
| P241-HC | 101Bio | - | Ask for price |
Leukemia - Multiple Myeloma Exosome RNA |
|||
| P241-MM | 101Bio | - | Ask for price |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) |
|||
| MBS643680-01mL | MyBiosource | 0.1mL | EUR 675 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) |
|||
| MBS643680-5x01mL | MyBiosource | 5x0.1mL | EUR 2880 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) |
|||
| MBS6004590-005mg | MyBiosource | 0.05(mg | EUR 630 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) |
|||
| MBS6004590-5x005mg | MyBiosource | 5x0.05mg | EUR 2680 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) |
|||
| MBS649502-01mg | MyBiosource | 0.1mg | EUR 630 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) |
|||
| MBS649502-5x01mg | MyBiosource | 5x0.1mg | EUR 2680 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (PE) |
|||
| MBS6157714-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (PE) |
|||
| MBS6157714-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (HRP) |
|||
| MBS6155997-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (HRP) |
|||
| MBS6155997-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (AP) |
|||
| MBS6131199-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (AP) |
|||
| MBS6131199-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (AP) |
|||
| MBS6134785-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (AP) |
|||
| MBS6134785-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) APC |
|||
| MBS6140088-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) APC |
|||
| MBS6140088-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) APC |
|||
| MBS6136502-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) APC |
|||
| MBS6136502-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (FITC) |
|||
| MBS6147108-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (FITC) |
|||
| MBS6147108-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (HRP) |
|||
| MBS6152411-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (HRP) |
|||
| MBS6152411-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (FITC) |
|||
| MBS6150694-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (FITC) |
|||
| MBS6150694-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (PE) |
|||
| MBS6161300-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (PE) |
|||
| MBS6161300-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (Biotin) |
|||
| MBS6141805-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (Biotin) |
|||
| MBS6141805-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (Biotin) |
|||
| MBS6145391-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (Biotin) |
|||
| MBS6145391-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 750) |
|||
| MBS6236817-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 750) |
|||
| MBS6236817-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 405) |
|||
| MBS6194117-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 405) |
|||
| MBS6194117-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 650) |
|||
| MBS6226142-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 650) |
|||
| MBS6226142-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 650) |
|||
| MBS6222087-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 650) |
|||
| MBS6222087-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 490) |
|||
| MBS6200737-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 490) |
|||
| MBS6200737-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 490) |
|||
| MBS6204792-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 490) |
|||
| MBS6204792-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 405) |
|||
| MBS6190062-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 405) |
|||
| MBS6190062-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 550) |
|||
| MBS6211412-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 550) |
|||
| MBS6211412-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 550) |
|||
| MBS6215467-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, P12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 550) |
|||
| MBS6215467-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 750) |
|||
| MBS6232762-01mL | MyBiosource | 0.1(mL | EUR 875 |
EXOSC5 (Exosome Complex Component RRP46, Chronic Myelogenous Leukemia Tumor Antigen 28, Exosome Component 5, Ribosomal RNA-processing Protein 46, p12B, CML28, RRP46, MGC111224, MGC12901) (MaxLight 750) |
|||
| MBS6232762-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
Exosome derived from human pleural effusion, leukemia chronic myelogenous (K-562 cell line) |
|||
| Exo-CH11 | Creative BioMart | Each | EUR 1147.5 |
|
Description: Exosome |
|||
Fluorescent labeled exosome derived from human pleural effusion, leukemia chronic myelogenous (K-562 cell line) |
|||
| Exo-F488-K-562 | Creative BioMart | Each | EUR 1593.75 |
|
Description: Exosome |
|||
Fluorescent labeled exosome derived from human pleural effusion, leukemia chronic myelogenous (K-562 cell line) |
|||
| Exo-F665-K-562 | Creative BioMart | Each | EUR 1249.5 |
|
Description: Exosome |
|||
Purified Exosomes: HTK562 Human Chronic Myelogenous Leukemia Cell Line |
|||
| EXOP-415A-1 | SBI | 50 µg | EUR 514 |
K-562 Cell Slide (Human (53yrs, Female) bone marrow, chronic myelogenous leukemia (CML)) (5 slides/pk) |
|||
| HCLS-17004 | Alpha Diagnostics | 1 pk | EUR 300 |
Psoriasis Exosome |
|||
| P141-PS | 101Bio | - | Ask for price |
Exosome Isolation kit (for serum & plasma -Exosome-RNA-NGS) |
|||
| P101NGS | 101Bio | - | Ask for price |
Lung Cancer Exosome |
|||
| P141-LG | 101Bio | - | Ask for price |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) |
|||
| MBS6002539-02mL | MyBiosource | 0.2(mL | EUR 695 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) |
|||
| MBS6002539-5x02mL | MyBiosource | 5x0.2mL | EUR 2975 |
Liver Cancer Exosome |
|||
| P141-LV | 101Bio | - | Ask for price |
Breast Cancer Exosome |
|||
| P141-BR | 101Bio | - | Ask for price |
Crohn's Disease Exosome |
|||
| P141-CR | 101Bio | - | Ask for price |
Kidney Cancer Exosome |
|||
| P141-KN | 101Bio | - | Ask for price |
Psoriasis Exosome RNA |
|||
| P241-PS | 101Bio | - | Ask for price |
Exosome Isolation Kit |
|||
| EIK01 | Creative BioMart | 2T | EUR 800 |
|
Description: Chromatography Reagents |
|||
Exosome Isolation Kit |
|||
| E601E001 | EnoGene | 20 tests | EUR 2500 |
Exosome Isolation Kit |
|||
| MBS8579443-20Tests | MyBiosource | 20Tests | EUR 2625 |
Exosome Isolation Kit |
|||
| MBS8579443-5x20Tests | MyBiosource | 5x20Tests | EUR 12240 |
Bladder Cancer Exosome |
|||
| P141-BL | 101Bio | - | Ask for price |
Thyroid Cancer Exosome |
|||
| P141-TH | 101Bio | - | Ask for price |
Prostate Cancer Exosome |
|||
| P141-PR | 101Bio | - | Ask for price |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (AP) |
|||
| MBS6297130-02mL | MyBiosource | 0.2mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (AP) |
|||
| MBS6297130-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (PE) |
|||
| MBS6297140-02mL | MyBiosource | 0.2mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (PE) |
|||
| MBS6297140-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (APC) |
|||
| MBS6297131-02mL | MyBiosource | 0.2mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (APC) |
|||
| MBS6297131-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (FITC) |
|||
| MBS6297133-02mL | MyBiosource | 0.2mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (FITC) |
|||
| MBS6297133-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
Bovine Leukemia Virus(Leukemia Virus) |
|||
| QY-E60121 | Qayee Biotechnology | 96T | EUR 511.2 |
Colorectal Cancer Exosome |
|||
| P141-CO | 101Bio | - | Ask for price |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (Biotin) |
|||
| MBS6297132-02mL | MyBiosource | 0.2mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (Biotin) |
|||
| MBS6297132-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
Rat Exosome ELISA Kit |
|||
| MBS3808774-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Rat Exosome ELISA Kit |
|||
| MBS3808774-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Rat Exosome ELISA Kit |
|||
| MBS3808774-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Rat Exosome ELISA Kit |
|||
| MBS3808774-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome) |
|||
| P101EZ | 101Bio | - | Ask for price |
Rheumatoid Arthritis Exosome |
|||
| P141-RA | 101Bio | - | Ask for price |
Exosome fluorescent staining |
|||
| S104 | 101Bio | - | EUR 800 |
Lung Cancer Exosome RNA |
|||
| P241-LG | 101Bio | - | Ask for price |
Nasopharyngeal Cancer Exosome |
|||
| P141-NA | 101Bio | - | Ask for price |
Lyophilized Exosome Standards |
|||
| ExoA375 | ImmunoStep | 100 μg | EUR 214.5 |
|
Description: Lyophilized Exosomes from A375 a human breast cancer cell line |
|||
Lyophilized Exosome Standards |
|||
| ExoHT29 | ImmunoStep | 100 μg | EUR 214.5 |
|
Description: Lyophilized Exosomes from HT-29, a human colon cancer cell line |
|||
Lyophilized Exosome Standards |
|||
| ExoMCF7 | ImmunoStep | 100 μg | EUR 214.5 |
|
Description: Lyophilized Exosomes from MCF-7, a human breast cancer cell line |
|||
Lyophilized Exosome Standards |
|||
| ExoPC3 | ImmunoStep | 100 μg | EUR 214.5 |
|
Description: Exosomes from PC-3, a human metastatic prostate cancer cell line |
|||
Lyophilized Exosome Standards |
|||
| ExoPLASMA | ImmunoStep | 100 μg | EUR 364.2 |
Lyophilized Exosome Standards |
|||
| ExoUrine | ImmunoStep | 100 μg | EUR 364.2 |
Diabetes (Type 1) Exosome |
|||
| P141-DB1 | 101Bio | - | Ask for price |
Diabetes (Type 2) Exosome |
|||
| P141-DB2 | 101Bio | - | Ask for price |
Liver Cancer Exosome RNA |
|||
| P241-LV | 101Bio | - | Ask for price |
Normal human exosome RNA |
|||
| P240 | 101Bio | - | EUR 1499 |
Exosome-TEM-easy Kit |
|||
| P130 | 101Bio | 10 rxn | EUR 489 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 405) |
|||
| MBS6297135-01mL | MyBiosource | 0.1mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 405) |
|||
| MBS6297135-5x01mL | MyBiosource | 5x0.1mL | EUR 4250 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 490) |
|||
| MBS6297136-01mL | MyBiosource | 0.1mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 490) |
|||
| MBS6297136-5x01mL | MyBiosource | 5x0.1mL | EUR 4250 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 550) |
|||
| MBS6297137-01mL | MyBiosource | 0.1mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 550) |
|||
| MBS6297137-5x01mL | MyBiosource | 5x0.1mL | EUR 4250 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 650) |
|||
| MBS6297138-01mL | MyBiosource | 0.1mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 650) |
|||
| MBS6297138-5x01mL | MyBiosource | 5x0.1mL | EUR 4250 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 750) |
|||
| MBS6297139-01mL | MyBiosource | 0.1mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (MaxLight 750) |
|||
| MBS6297139-5x01mL | MyBiosource | 5x0.1mL | EUR 4250 |
Exosome Precipitation Solution |
|||
| EPStep | ImmunoStep | 12 ml | EUR 242 |
|
Description: Exosome Precipitation Solution - 12ml |
|||
Breast Cancer Exosome RNA |
|||
| P241-BR | 101Bio | - | Ask for price |
Crohn's Disease Exosome RNA |
|||
| P241-CR | 101Bio | - | Ask for price |
Kidney Cancer Exosome RNA |
|||
| P241-KN | 101Bio | - | Ask for price |
Exosome derived from milk |
|||
| Exo-BF05 | Creative BioMart | Each | EUR 1462 |
|
Description: Exosome |
|||
Bladder Cancer Exosome RNA |
|||
| P241-BL | 101Bio | - | Ask for price |
Thyroid Cancer Exosome RNA |
|||
| P241-TH | 101Bio | - | Ask for price |
Exosome isolation Solution - Cell Media/ Urine (easy version of P100, 95% pure exosome) |
|||
| P100EZ | 101Bio | - | Ask for price |
Prostate Cancer Exosome RNA |
|||
| P241-PR | 101Bio | - | Ask for price |
Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome) sample |
|||
| P101EZ--sample | 101Bio | - | Ask for price |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (Azide free) (HRP) |
|||
| MBS6297134-02mL | MyBiosource | 0.2mL | EUR 980 |
EXOSC1, CT (EXOSC1, CSL4, Exosome complex component CSL4, Exosome component 1) (Azide free) (HRP) |
|||
| MBS6297134-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
Melanoma (skin cancer) Exosome |
|||
| P141-MN | 101Bio | - | Ask for price |
Exosome Component 9 Peptide |
|||
| 46-967P | ProSci | 0.1 mg | EUR 405.6 |
|
Description: (CT) PMSCL1 Peptide |
|||
Exosome Component 10 Protein |
|||
| abx261805-10mg | Abbexa | 10 mg | EUR 4987.5 |
Exosome Component 10 Protein |
|||
| 20-abx261805 | Abbexa |
|
|
Exosome Component 10 Protein |
|||
| abx261805-5mg | Abbexa | 5 mg | EUR 325 |
Exosome Component 4 Protein |
|||
| abx261954-10mg | Abbexa | 10 mg | EUR 4625 |
Exosome Component 4 Protein |
|||
| 20-abx261954 | Abbexa |
|
|
Exosome Component 4 Protein |
|||
| abx261954-5mg | Abbexa | 5 mg | EUR 325 |
Exosome Component 9 Protein |
|||
| abx262123-10mg | Abbexa | 10 mg | EUR 325 |
Exosome Component 9 Protein |
|||
| 20-abx262123 | Abbexa |
|
|
Exosome Component 9 Protein |
|||
| abx262123-25mg | Abbexa | 25 mg | EUR 5237.5 |
Exosome Component 9 Protein |
|||
| abx262123-5mg | Abbexa | 5 mg | EUR 225 |
Exosome Component 5 Protein |
|||
| abx260873-10g | Abbexa | 10 µg | EUR 325 |
Exosome Component 5 Protein |
|||
| 20-abx260873 | Abbexa |
|
|
Exosome Component 5 Protein |
|||
| abx260873-2g | Abbexa | 2 µg | EUR 225 |
Exosome Component 7 Protein |
|||
| abx261347-100g | Abbexa | 100 µg | EUR 325 |
Exosome Component 7 Protein |
|||
| abx261347-20g | Abbexa | 20 µg | EUR 225 |
Exosome Component 7 Protein |
|||
| 20-abx261347 | Abbexa |
|
|
Exosome Component 8 Protein |
|||
| abx262850-10mg | Abbexa | 10 mg | EUR 325 |
Exosome Component 8 Protein |
|||
| 20-abx262850 | Abbexa |
|
|
Exosome Component 8 Protein |
|||
| abx262850-25mg | Abbexa | 25 mg | EUR 6575 |
Exosome Component 8 Protein |
|||
| abx262850-5mg | Abbexa | 5 mg | EUR 225 |
Exosome Component 3 Protein |
|||
| 20-abx263422 | Abbexa |
|
|
Exosome Component 3 Protein |
|||
| abx263422-1mg | Abbexa | 1 mg | EUR 225 |
Exosome Component 3 Protein |
|||
| abx263422-2mg | Abbexa | 2 mg | EUR 325 |
Exosome Component 3 Protein |
|||
| abx263422-5mg | Abbexa | 5 mg | EUR 1600 |
Exosome Component 1 Protein |
|||
| 20-abx263423 | Abbexa |
|
|
Exosome Component 1 Protein |
|||
| abx263423-1mg | Abbexa | 1 mg | EUR 225 |
Exosome Component 1 Protein |
|||
| abx263423-2mg | Abbexa | 2 mg | EUR 325 |
Exosome Component 1 Protein |
|||
| abx263423-5mg | Abbexa | 5 mg | EUR 1600 |
Leukemia-Spleen Tissue Slide (Lymphoma/Leukemia) |
|||
| 11-601-10um | ProSci | 10 um | EUR 241.8 |
Leukemia-Spleen Tissue Slide (Lymphoma/Leukemia) |
|||
| 11-601-4um | ProSci | 4 um | EUR 216.6 |
Leukemia-Spleen Tissue Slide (Lymphoma/Leukemia) |
|||
| MBS154299-10um | MyBiosource | 10um | EUR 210 |
Leukemia-Spleen Tissue Slide (Lymphoma/Leukemia) |
|||
| MBS154299-4um | MyBiosource | 4um | EUR 195 |
Leukemia-Spleen Tissue Slide (Lymphoma/Leukemia) |
|||
| MBS154299-5x10um | MyBiosource | 5x10um | EUR 920 |
Uterine Corpus Cancer Exosome |
|||
| P141-UT | 101Bio | - | Ask for price |
Colorectal Cancer Exosome RNA |
|||
| P241-CO | 101Bio | - | Ask for price |
EXOCET Exosome Quantitation Kit |
|||
| EXOCET96A-1 | SBI | 96 reactions | EUR 462 |
Non-Hodgkin lymphoma Exosome |
|||
| P141-NH | 101Bio | - | Ask for price |
Urine Exosome Purification Kit |
|||
| 57740 | Norgen Biotek Corp | 4 Preps | EUR 12 |
Lyophilized Exosome from Serum |
|||
| ExoSERUM | ImmunoStep | 100 | EUR 214.5 |
|
Description: Lyophilized Exosome from Serum |
|||
Exo-APC Exosome FACS stain |
|||
| EXOFLOW810A-1 | SBI | 20 reactions | EUR 188 |
Uterine Cervical Cancer Exosome |
|||
| P141-UC | 101Bio | - | Ask for price |
Saliva Exosome Purification Kit |
|||
| 65300 | Norgen Biotek Corp | 50 Preps | EUR 491.4 |
Exosome isolation Solution - Cell Media/ Urine (easy version of P100, 95% pure exosome) sample |
|||
| P100EZ-sample | 101Bio | - | Ask for price |
Exo-FITC Exosome FACS stain |
|||
| EXOFLOW800A-1 | SBI | 20 reactions | EUR 188 |
Rheumatoid Arthritis Exosome RNA |
|||
| P241-RA | 101Bio | - | Ask for price |
Diabetes (Type 1) Exosome RNA |
|||
| P241-DB1 | 101Bio | - | Ask for price |
Diabetes (Type 2) Exosome RNA |
|||
| P241-DB2 | 101Bio | - | Ask for price |
Nasopharyngeal Cancer Exosome RNA |
|||
| P241-NA | 101Bio | - | Ask for price |
Fluorescent Exosome Standard (Urine ) |
|||
| ESF-15 | Creative Biolabs | 100 µg | EUR 2067.6 |
|
Description: Fluorescent exosomes are labeled with green dye, which offer a stable fluorescent labeling. |
|||
FluoroCet Exosome Quantitation Kit |
|||
| FCET96A-1 | SBI | 96 reactions | EUR 661 |
EXOSC1 (CSL4, Exosome Complex Component CSL4, Exosome Component 1, CGI-108, SKI4, Ski4p, hCsl4p, p13) |
|||
| MBS644731-005mg | MyBiosource | 0.05mg | EUR 630 |
EXOSC1 (CSL4, Exosome Complex Component CSL4, Exosome Component 1, CGI-108, SKI4, Ski4p, hCsl4p, p13) |
|||
| MBS644731-5x005mg | MyBiosource | 5x0.05mg | EUR 2680 |
EXOSC1 (CSL4, Exosome Complex Component CSL4, Exosome Component 1, CGI-108, SKI4, Ski4p, hCsl4p, p13) |
|||
| MBS6002399-01mg | MyBiosource | 0.1(mg | EUR 630 |
EXOSC1 (CSL4, Exosome Complex Component CSL4, Exosome Component 1, CGI-108, SKI4, Ski4p, hCsl4p, p13) |
|||
| MBS6002399-5x01mg | MyBiosource | 5x0.1mg | EUR 2680 |
Urine Exosome RNA Isolation Kit |
|||
| 47200 | Norgen Biotek Corp | 50 Preps | EUR 429 |
LiqBiopsy Tumor Exosome RNA Kit |
|||
| K1254-24 | Biovision | each | EUR 1332 |
Serum-free Medium (For Exosome) |
|||
| JOT-EV02-09-01 | Jotbody | 500 mL | EUR 189.48 |
Exosome Isolation kit (for urine) |
|||
| P120L | 101Bio | 40 rxn | EUR 769 |
Exosome Isolation kit (for urine) |
|||
| P120S | 101Bio | 2 rxn | EUR 69 |
Exosome Component 8 (EXOSC8) Antibody |
|||
| abx003377-100l | Abbexa | 100 µl | EUR 400 |