exosomes promote restoration from traumatic mind damage by way of microglia

ataxin

Mechanical stress promotes angiogenesis by means of fibroblast exosomes

 

Background: Mechanical stress can induce a number of purposeful modifications in vascular endothelial cells, together with proliferation, differentiation, and migration. Moreover, human fibroblasts are inclined to exterior mechanical stress. On this work, we investigated whether or not mechanical stress can induce exosome secretion from fibroblasts to modulate angiogenesis.

 

Strategies: A CCK-Eight cell proliferation assay was used to find out mechanical parameters. Then, exosomes from fibroblasts had been remoted and characterised with regard to focus and markers. We subsequently explored the impact of exosomes on proliferation, migration, and angiogenesis. Moreover, high-throughput sequencing was used to display screen differentially expressed miRNAs within the mechanical stress-induced exosomes.

 

Outcomes: A static stretching of 15% considerably enhanced the cell viability of the fibroblasts (p < 0.05) and considerably induced the secretion of exosomes from the fibroblasts, which had a stronger internalization capacity. Additional experiments demonstrated that the presence of static stretching-induced exosomes considerably elevated cell proliferation, migration, and angiogenesis by regulating the Erk1/2 signaling pathway. Moreover, 12 up-regulated and 12 down-regulated candidate miRNAs had been discriminated within the static stretching-induced exosomes.

 

Conclusion: Our findings conclusively exhibit that static stretching-derived exosomes from fibroblasts promote angiogenesis by means of differentially expressed miRNAs, offering novel insights into the molecular mechanism by which mechanical stress influences angiogenesis.

ataxin

ataxin

Allophycocyanin (APC) Antibody Labeling Kit
20-abx098280
  • EUR 509.00
  • EUR 377.00
  • 1 mg
  • 200 ug
  • Shipped within 5-10 working days.
Phycoerythrin (PE) Antibody Labeling Kit
20-abx098281
  • EUR 509.00
  • EUR 377.00
  • 1 mg
  • 200 ug
  • Shipped within 5-10 working days.
EZLabel? Antibody HRP Labeling Kit
K4310-1
EUR 697
EZLabel? Antibody RPE Labeling Kit
K4313-1
EUR 805
EZLabel? Antibody FITC Labeling Kit
K831-5
EUR 365
EZLabel? Antibody Biotin Labeling Kit
K834-5
EUR 376
EZLabel? Antibody Cy3 Labeling Kit
K836-5
EUR 354
EZLabel? Antibody Cy5 Labeling Kit
K838-5
EUR 354
Mix-n-Stain CF350 Antibody Labeling Kit, 1x(50-100ug) labeling
92230 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF405S Antibody Labeling Kit, 1x(50-100ug) labeling
92231 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF405M Antibody Labeling Kit, 1x(50-100ug) labeling
92232 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF488A Antibody Labeling Kit, 1x(50-100ug) labeling
92233 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF555 Antibody Labeling Kit, 1x(50-100ug) labeling
92234 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF568 Antibody Labeling Kit, 1x(50-100ug) labeling
92235 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF594 Antibody Labeling Kit, 1x(50-100ug) labeling
92236 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF633 Antibody Labeling Kit, 1x(50-100ug) labeling
92237 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF647 Antibody Labeling Kit, 1x(50-100ug) labeling
92238 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF660C Antibody Labeling Kit, 1x(50-100ug) labeling
92239 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF680 Antibody Labeling Kit, 1x(50-100ug) labeling
92240 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF750 Antibody Labeling Kit, 1x(50-100ug) labeling
92241 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF770 Antibody Labeling Kit, 1x(50-100ug) labeling
92242 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF660R Antibody Labeling Kit, 1x(50-100ug) labeling
92243 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain Biotin Antibody Labeling Kit, 1x(50-100ug) labeling
92244 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF640R Antibody Labeling Kit, 1x(50-100ug) labeling
92245 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF680R Antibody Labeling Kit, 1x(50-100ug) labeling
92246 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF543 Antibody Labeling Kit, 1x(50-100ug) labeling
92247 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF790 Antibody Labeling Kit, 1x(50-100ug) labeling
92248 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF350 Antibody Labeling Kit, 1x(20-50ug) labeling
92250 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF405S Antibody Labeling Kit, 1x(20-50ug) labeling
92251 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF405M Antibody Labeling Kit, 1x(20-50ug) labeling
92252 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF488A Antibody Labeling Kit, 1x(20-50ug) labeling
92253 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF555 Antibody Labeling Kit, 1x(20-50ug) labeling
92254 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF568 Antibody Labeling Kit, 1x(20-50ug) labeling
92255 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF594 Antibody Labeling Kit, 1x(20-50ug) labeling
92256 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF633 Antibody Labeling Kit, 1x(20-50ug) labeling
92257 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF640R Antibody Labeling Kit, 1x(20-50ug) labeling
92258 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF647 Antibody Labeling Kit, 1x(20-50ug) labeling
92259 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF660C Antibody Labeling Kit, 1x(20-50ug) labeling
92260 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF660R Antibody Labeling Kit, 1x(20-50ug) labeling
92261 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF680 Antibody Labeling Kit, 1x(20-50ug) labeling
92262 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF680R Antibody Labeling Kit, 1x(20-50ug) labeling
92263 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF750 Antibody Labeling Kit, 1x(20-50ug) labeling
92264 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF770 Antibody Labeling Kit, 1x(20-50ug) labeling
92265 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain Biotin Antibody Labeling Kit, 1x(20-50ug) labeling
92266 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF543 Antibody Labeling Kit, 1x(20-50ug) labeling
92267 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF790 Antibody Labeling Kit, 1x(20-50ug) labeling
92268 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF350 Antibody Labeling Kit, 1x(5-20ug) labeling
92270 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF405S Antibody Labeling Kit, 1x(5-20ug) labeling
92271 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF405M Antibody Labeling Kit, 1x(5-20ug) labeling
92272 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF488A Antibody Labeling Kit, 1x(5-20ug) labeling
92273 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF555 Antibody Labeling Kit, 1x(5-20ug) labeling
92274 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF568 Antibody Labeling Kit, 1x(5-20ug) labeling
92275 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF594 Antibody Labeling Kit, 1x(5-20ug) labeling
92276 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF633 Antibody Labeling Kit, 1x(5-20ug) labeling
92277 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF640R Antibody Labeling Kit, 1x(5-20ug) labeling
92278 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF647 Antibody Labeling Kit, 1x(5-20ug) labeling
92279 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF660C Antibody Labeling Kit, 1x(5-20ug) labeling
92280 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF660R Antibody Labeling Kit, 1x(5-20ug) labeling
92281 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF680 Antibody Labeling Kit, 1x(5-20ug) labeling
92282 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF680R Antibody Labeling Kit, 1x(5-20ug) labeling
92283 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF750 Antibody Labeling Kit, 1x(5-20ug) labeling
92284 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF770 Antibody Labeling Kit, 1x(5-20ug) labeling
92285 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain Biotin Antibody Labeling Kit, 1x(5-20ug) labeling
92286 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF543 Antibody Labeling Kit, 1x(5-20ug) labeling
92287 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF790 Antibody Labeling Kit, 1x(5-20ug) labeling
92288 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF532 Antibody Labeling Kit, 1x(5-20ug) labeling
92289 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF532 Antibody Labeling Kit, 1x(20-50ug) labeling
92290 1Kit
EUR 172
Description: Minimum order quantity: 1 unit of 1Kit
Mix-n-Stain CF532 Antibody Labeling Kit, 1x(50-100ug) labeling
92291 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain FITC Antibody Labeling Kit, 1x(5-20ug) labeling
92294 1KIT
EUR 120
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain FITC Antibody Labeling Kit, 1x(20-50ug) labeling
92295 1KIT
EUR 132
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain FITC Antibody Labeling Kit, 1x(50-100ug) labeling
92296 1KIT
EUR 143
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain RPE Antibody Labeling Kit, 1x(5-20ug) labeling
92297 1KIT
EUR 166
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain RPE Antibody Labeling Kit, 1x(25-50ug) labeling
92298 1KIT
EUR 177
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain RPE Antibody Labeling Kit, 1x(50-100ug) labeling
92299 1KIT
EUR 189
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain HRP Antibody Labeling Kit, 1x(10-20ug) labeling
92300 1KIT
EUR 155
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain HRP Antibody Labeling Kit, 1x(25-50ug) labeling
92301 1KIT
EUR 166
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain HRP Antibody Labeling Kit, 1x(50-100ug) labeling
92302 1KIT
EUR 177
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF405L Antibody Labeling Kit, 1x(5-20ug) labeling
92303 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF405L Antibody Labeling Kit, 1x(20-50ug) labeling
92304 1Kit
EUR 172
Description: Minimum order quantity: 1 unit of 1Kit
Mix-n-Stain CF405L Antibody Labeling Kit, 1x(50-100ug) labeling
92305 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain APC Antibody Labeling Kit, 1x(25-50ug) labeling
92306 1KIT
EUR 177
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain APC Antibody Labeling Kit, 1x(50-100ug) labeling
92307 1KIT
EUR 189
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain PerCP Antibody Labeling Kit, 1x(25-50ug) labeling
92308 1KIT
EUR 177
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain PerCP Antibody Labeling Kit, 1x(50-100ug) labeling
92309 1KIT
EUR 189
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF430 Antibody Labeling Kit, 1x(5-20ug) labeling
92316 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF430 Antibody Labeling Kit, 1x(20-50ug) labeling
92317 1Kit
EUR 195
Description: Minimum order quantity: 1 unit of 1Kit
Mix-n-Stain CF430 Antibody Labeling Kit, 1x(50-100ug) labeling
92318 1KIT
EUR 207
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF440 Antibody Labeling Kit, 1x(5-20ug) labeling
92319 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT
Mix-n-Stain CF440 Antibody Labeling Kit, 1x(20-50ug) labeling
92320 1Kit
EUR 195
Description: Minimum order quantity: 1 unit of 1Kit
Mix-n-Stain CF440 Antibody Labeling Kit, 1x(50-100ug) labeling
92321 1KIT
EUR 207
Description: Minimum order quantity: 1 unit of 1KIT

MSC-derived exosomes promote restoration from traumatic mind damage by way of microglia/macrophages in rat

 

Traumatic mind damage (TBI) is a number one reason behind morbidity and mortality in younger people worldwide. There may be presently no efficient scientific therapy for TBI, however mesenchymal stem cell-derived exosomes have exhibited promising therapeutic results.

On this examine, we carried out intracerebroventricular microinjection of human adipose mesenchymal stem cell (hADSC)-derived exosomes (hADSC-ex) in a weight-drop-induced TBI rat mannequin. We discovered that hADSC-ex promoted purposeful restoration, suppressed neuroinflammation, lowered neuronal apoptosis, and elevated neurogenesis in TBI rats.

The therapeutic results of hADSC-ex had been akin to these of hADSC. Sequential in vivo imaging revealed growing aggregation of DiR-labeled hADSC-ex within the lesion space. Immunofluorescent staining of coronal mind sections and first combined neural cell cultures revealed distinct overlap between CM-DiI-labeled hADSC-ex and microglia/macrophages, indicating that hADSC-ex had been primarily taken up by microglia/macrophages.

In a lipopolysaccharide-induced inflammatory mannequin, hADSC-ex suppressed microglia/macrophage activation by inhibiting nuclear issue κB and P38 mitogen-activated protein kinase signaling. These information counsel that hADSC-ex particularly enter microglia/macrophages and suppress their activation throughout mind damage, thereby inhibiting irritation and facilitating purposeful restoration.

In addition they supply new perception into the mobile concentrating on, uptake and migration of hADSC-ex, and supply a theoretical foundation for brand spanking new therapeutic methods for central nervous system ailments.

The Position of Exosomes in Stemness and Neurodegenerative Ailments-Chemoresistant-Most cancers Therapeutics and Phytochemicals

 

  • Exosomes exhibit a variety of organic properties and features within the residing organisms. They’re nanometric automobiles and used for delivering medication, as they’re biocompatible and minimally immunogenic. Exosomal secretions derived from most cancers cells contribute to metastasis, immortality, angiogenesis, tissue invasion, stemness and chemo/radio-resistance.

 

  • Exosome-derived microRNAs (miRNAs) and lengthy non-coding RNAs (lnc RNAs) are concerned within the pathophysiology of cancers and neurodegenerative ailments. As an illustration, exosomes derived from mesenchymal stromal cells, astrocytes, macrophages, and acute myeloid leukemia (AML) cells are concerned within the most cancers development and stemness as they induce chemotherapeutic drug resistance in a number of most cancers cells.

 

  • This evaluation lined the current analysis advances in understanding the position of exosomes in most cancers development, metastasis, angiogenesis, stemness and drug resistance by illustrating the modulatory results of exosomal cargo (ex. miRNA, lncRNAs, and so on.) on cell signaling pathways concerned in most cancers development and most cancers stem cell progress and growth. Current stories have implicated exosomes even within the therapy of a number of cancers.

 

  • As an illustration, exosomes-loaded with novel anti-cancer medication reminiscent of phytochemicals, tumor-targeting proteins, anticancer peptides, nucleic acids are identified to intrude with drug resistance pathways in a number of most cancers cell traces. As well as, this evaluation depicted the necessity to develop exosome-based novel diagnostic biomarkers for early detection of cancers and neurodegenerative illness.

 

  • Moreover, the position of exosomes in stroke and oxidative stress-mediated neurodegenerative ailments together with Alzheimer’s illness (AD), and Parkinson’s illness (PD) can also be mentioned on this article..

 

Mix-n-Stain Biotin Antibody Labeling Kit, 1x(20-50ug) labeling

92266 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain Biotin Antibody Labeling Kit, 1x(5-20ug) labeling

92286 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT

Anti-human CD14 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC00137-Biotin 100µg
EUR 233
Description: Mouse Monoclonal human CD14 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD11b Monoclonal Antibody Biotin Conjugated, Flow Validated

FC00144-Biotin 100µg
EUR 152
Description: Mouse Monoclonal human CD11b Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD19 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC00154-Biotin 100µg
EUR 152
Description: Mouse Monoclonal human CD19 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD38 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC00193-Biotin 100µg
EUR 152
Description: Mouse Monoclonal human CD38 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD25 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC00214-Biotin 100µg
EUR 233
Description: Mouse Monoclonal human CD25 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD4 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC00344-Biotin 100µg
EUR 152
Description: Mouse Monoclonal human CD4 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD5 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC00480-Biotin 100µg
EUR 233
Description: Mouse Monoclonal human CD5 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD45 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC00555-Biotin 100µg
EUR 152
Description: Mouse Monoclonal human CD45 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD2 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC00570-Biotin 100µg
EUR 233
Description: Mouse Monoclonal human CD2 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD71 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC00591-Biotin 100µg
EUR 245
Description: Mouse Monoclonal human CD71 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD62L Monoclonal Antibody Biotin Conjugated, Flow Validated

FC00652-Biotin 100µg
EUR 233
Description: Mouse Monoclonal human CD62L Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD59 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC00914-Biotin 100µg
EUR 265
Description: Mouse Monoclonal human CD59 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD117 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC01335-Biotin 100μg
EUR 224
Description: Mouse Monoclonal human CD117 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD32 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC01450-Biotin 100µg
EUR 233
Description: Mouse Monoclonal human CD32 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD90 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC01818-Biotin 100µg
EUR 268
Description: Mouse Monoclonal human CD90 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD7 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC01974-Biotin 100µg
EUR 233
Description: Mouse Monoclonal human CD7 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD235a Monoclonal Antibody Biotin Conjugated, Flow Validated

FC02184-Biotin 100µg
EUR 245
Description: Mouse Monoclonal human CD235a Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD8 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC02236-Biotin 100µg
EUR 152
Description: Mouse Monoclonal human CD8 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-Human VEGI Monoclonal Antibody Biotin Conjugated, Flow Validated

FC02402-Biotin Various Sizes
EUR 497
Description: Mouse Monoclonal Human VEGI Antibody Biotin Conjugated, Flow Validated. Validated in WB and tested in Human.

Anti-human CD3 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC02675-Biotin 100µg
EUR 152
Description: Mouse Monoclonal human CD3 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD20 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC03780-Biotin 100µg
EUR 233
Description: Mouse Monoclonal human CD20 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD10 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC04065-Biotin 100µg
EUR 189
Description: Mouse Monoclonal human CD10 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD57 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC09548-Biotin 100µg
EUR 245
Description: Mouse Monoclonal human CD57 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Exosome Component 5 (EXOSC5) Antibody (Biotin)

20-abx311413
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Exosome Component 3 (EXOSC3) Antibody (Biotin)

20-abx312072
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Exosome Component 1 (EXOSC1) Antibody (Biotin)

20-abx312488
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Exosome Component 8 (EXOSC8) Antibody (Biotin)

20-abx310196
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Exosome Component 10 (EXOSC10) Antibody (Biotin)

20-abx335642
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Anti-human HLA-DR Monoclonal Antibody Biotin Conjugated, Flow Validated

FC00568-Biotin 100µg
EUR 233
Description: Mouse Monoclonal human HLA-DR Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD55/Daf Monoclonal Antibody Biotin Conjugated, Flow Validated

FC00910-Biotin 100µg
EUR 233
Description: Mouse Monoclonal human CD55/Daf Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD33/Siglec 3 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC01508-Biotin 100µg
EUR 234
Description: Mouse Monoclonal human CD33/Siglec 3 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD22/Siglec 2 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC01572-Biotin 100µg
EUR 233
Description: Mouse Monoclonal human CD22/Siglec 2 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Exosome complex exonuclease DIS3 (DIS3) Antibody (Biotin)

20-abx335639
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Labeling Tape, Blue

TP001B 1ROLLS, 1 UNIT
EUR 53.68
  • Product category: Labware/Lab Supplies/Labels

Labeling Tape, Red

TP002R 1ROLLS, 1 UNIT
EUR 53.68
  • Product category: Labware/Lab Supplies/Labels

Labeling Tape, White

TP003W 1ROLLS, 1 UNIT
EUR 53.68
  • Product category: Labware/Lab Supplies/Labels

Labeling Tape, Yellow

TP004Y 1ROLLS, 1 UNIT
EUR 53.68
  • Product category: Labware/Lab Supplies/Labels

Psoriasis Exosome

P141-PS NULL
EUR 0

Mouse anti-human CD7 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC01974-1-Biotin 100µg
EUR 233
Description: Mouse Monoclonal Mouse human CD7 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-cTnI McAb (labeling)

E63C00404 100ug
EUR 382

Anti-PCT McAb (labeling)

E63C00904 100ug
EUR 382

Exosome precipitation Solution

EPStep 12 ml
EUR 277.5

Lyophilized Exosome Standards

ExoA375 100 μg
EUR 303.5

Lyophilized Exosome Standards

ExoHT29 100 μg
EUR 303.5

Lyophilized Exosome Standards

ExoMCF7 100 μg
EUR 303.5

Lyophilized Exosome Standards

ExoPC3 100 μg
EUR 303.5

Lyophilized Exosome Standards

ExoPLASMA 100 μg
EUR 303.5

Lyophilized Exosome Standards

ExoUrine 100 μg
EUR 303.5

Leukemia - ALL Exosome

P141-ALL NULL
EUR 0

Leukemia - AML Exosome

P141-AML NULL
EUR 0

Bladder Cancer Exosome

P141-BL NULL
EUR 0

Breast Cancer Exosome

P141-BR NULL
EUR 0

Leukemia - CLL Exosome

P141-CLL NULL
EUR 0

Leukemia - CML Exosome

P141-CML NULL
EUR 0

Colorectal Cancer Exosome

P141-CO NULL
EUR 0

Crohn's Disease Exosome

P141-CR NULL
EUR 0

Kidney Cancer Exosome

P141-KN NULL
EUR 0

Lung Cancer Exosome

P141-LG NULL
EUR 0

Liver Cancer Exosome

P141-LV NULL
EUR 0

Nasopharyngeal Cancer Exosome

P141-NA NULL
EUR 0

Prostate Cancer Exosome

P141-PR NULL
EUR 0

Rheumatoid Arthritis Exosome

P141-RA NULL
EUR 0

Thyroid Cancer Exosome

P141-TH NULL
EUR 0

Psoriasis Exosome RNA

P241-PS NULL
EUR 0

Mix-n-Stain CF350 Antibody Labeling Kit, 1x(50-100ug) labeling

92230 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF405S Antibody Labeling Kit, 1x(50-100ug) labeling

92231 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF405M Antibody Labeling Kit, 1x(50-100ug) labeling

92232 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF488A Antibody Labeling Kit, 1x(50-100ug) labeling

92233 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF555 Antibody Labeling Kit, 1x(50-100ug) labeling

92234 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF568 Antibody Labeling Kit, 1x(50-100ug) labeling

92235 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF594 Antibody Labeling Kit, 1x(50-100ug) labeling

92236 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF633 Antibody Labeling Kit, 1x(50-100ug) labeling

92237 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF647 Antibody Labeling Kit, 1x(50-100ug) labeling

92238 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF660C Antibody Labeling Kit, 1x(50-100ug) labeling

92239 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF680 Antibody Labeling Kit, 1x(50-100ug) labeling

92240 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF750 Antibody Labeling Kit, 1x(50-100ug) labeling

92241 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF770 Antibody Labeling Kit, 1x(50-100ug) labeling

92242 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF660R Antibody Labeling Kit, 1x(50-100ug) labeling

92243 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF640R Antibody Labeling Kit, 1x(50-100ug) labeling

92245 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF680R Antibody Labeling Kit, 1x(50-100ug) labeling

92246 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF543 Antibody Labeling Kit, 1x(50-100ug) labeling

92247 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF790 Antibody Labeling Kit, 1x(50-100ug) labeling

92248 1KIT
EUR 185
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF350 Antibody Labeling Kit, 1x(20-50ug) labeling

92250 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF405S Antibody Labeling Kit, 1x(20-50ug) labeling

92251 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF405M Antibody Labeling Kit, 1x(20-50ug) labeling

92252 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF488A Antibody Labeling Kit, 1x(20-50ug) labeling

92253 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF555 Antibody Labeling Kit, 1x(20-50ug) labeling

92254 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF568 Antibody Labeling Kit, 1x(20-50ug) labeling

92255 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF594 Antibody Labeling Kit, 1x(20-50ug) labeling

92256 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF633 Antibody Labeling Kit, 1x(20-50ug) labeling

92257 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF640R Antibody Labeling Kit, 1x(20-50ug) labeling

92258 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF647 Antibody Labeling Kit, 1x(20-50ug) labeling

92259 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF660C Antibody Labeling Kit, 1x(20-50ug) labeling

92260 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF660R Antibody Labeling Kit, 1x(20-50ug) labeling

92261 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF680 Antibody Labeling Kit, 1x(20-50ug) labeling

92262 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF680R Antibody Labeling Kit, 1x(20-50ug) labeling

92263 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF750 Antibody Labeling Kit, 1x(20-50ug) labeling

92264 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF770 Antibody Labeling Kit, 1x(20-50ug) labeling

92265 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF543 Antibody Labeling Kit, 1x(20-50ug) labeling

92267 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF790 Antibody Labeling Kit, 1x(20-50ug) labeling

92268 1KIT
EUR 172
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF350 Antibody Labeling Kit, 1x(5-20ug) labeling

92270 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF405S Antibody Labeling Kit, 1x(5-20ug) labeling

92271 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF405M Antibody Labeling Kit, 1x(5-20ug) labeling

92272 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF488A Antibody Labeling Kit, 1x(5-20ug) labeling

92273 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF555 Antibody Labeling Kit, 1x(5-20ug) labeling

92274 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF568 Antibody Labeling Kit, 1x(5-20ug) labeling

92275 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF594 Antibody Labeling Kit, 1x(5-20ug) labeling

92276 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT

Mix-n-Stain CF633 Antibody Labeling Kit, 1x(5-20ug) labeling

92277 1KIT
EUR 161
Description: Minimum order quantity: 1 unit of 1KIT

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