Pleiotropic Results of Exosomes as a Remedy for Stroke Restoration

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Pre-incubation with human umbilical twine derived mesenchymal stem cells-exosomes prevents cisplatin-induced renal tubular epithelial cell harm

Objective: The administration of cisplatin is proscribed as a result of its nephrotoxicity, and prevention of this nephrotoxicity of cisplatin is troublesome. Mesenchymal stem cell (MSC)-derived exosomes have been implicated as a novel therapeutic method for tissue harm.

 

Outcomes: In vitro, the NRK cells pre-incubated with HUMSC-exosomes elevated the Cp-inhibited cell viability, proliferation exercise, and the cell proportion in G1-phase and inhibited Cp-induced cell apoptosis. Moreover, the expression ranges of apoptotic marker proteins Bim, Dangerous, Bax, cleaved caspase-3, and cleaved caspase-9 induced by Cp within the NRK cells had been decreased by pre-incubating with HUMSC-exosomes.

 

Conclusion: Our findings indicated that the exosomes from HUMSCs can successfully enhance the survival price and inhibit cell apoptosis of NRK cells. Subsequently, pre-treatment of HUMSC-exosomes could also be a brand new methodology to enhance the therapeutic impact of cisplatin.

 

Sufferers and strategies: Exosomes had been remoted from human umbilical twine derived mesenchymal stem cells (HUMSCs). Co-culture of regular rat renal tubular epithelial cells (NRK) and the absorption of exogenous exosomes by NRK cells had been examined in vitro. Then the NRK cells had been incubated with exosomes from HUMSCs and cisplatin (Cp). Cells had been harvested for MTT assay, cloning formation, circulate cytometry, and Western blot.

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Exosome Isolation kit (for cell culture media)

P100L 40 rxn
EUR 1149

ExoQualiTM Exosome Isolation Kit (Stem Cell Media)

CEIK-002L-10T 10 T Ask for price

ExoQualiTM Exosome Isolation Kit (Stem Cell Media)

CEIK-002L-30T 30 T Ask for price

EXO-Prep for exosome isolation from Cell Media

HBM-EXP-C25 25 ml (25 react)
EUR 234.36

ExoPure? Reagent (Overall Exosome Isolation, cell media)

M1002-25 each
EUR 992.4

ExoPure? Reagent (Overall Exosome Isolation, cell media)

M1002-50 each
EUR 1083.6

Exosome Isolation kit (for stem cell culture media)

P107 10 rxn
EUR 199

Exosome Isolation kit (for stem cell culture media)

P107S 2 rxn
EUR 69

VEX Exosome Isolation Reagent (from cell culture media)

R601 50 ml
EUR 706.8

Exosome Isolation kit (for urine)

P120L 40 rxn
EUR 769

Exosome Isolation kit (for urine)

P120S 2 rxn
EUR 69

GPC1 Capture Exosome Isolation Kit

E601E004 20 tests
EUR 2500

CD63 Capture Exosome Isolation Kit

E601E005 20 tests
EUR 2500

CD81 Capture Exosome Isolation Kit

E601E006 20 tests
EUR 2500

GPC1 Capture Exosome Isolation Kit

MBS8579446-20Tests 20Tests
EUR 2625

GPC1 Capture Exosome Isolation Kit

MBS8579446-5x20Tests 5x20Tests
EUR 12240

CD63 Capture Exosome Isolation Kit

MBS8579447-20Tests 20Tests
EUR 2625

CD63 Capture Exosome Isolation Kit

MBS8579447-5x20Tests 5x20Tests
EUR 12240

CD81 Capture Exosome Isolation Kit

MBS8579448-20Tests 20Tests
EUR 2625

CD81 Capture Exosome Isolation Kit

MBS8579448-5x20Tests 5x20Tests
EUR 12240

Exosome isolation Solution - Cell Media/ Urine (easy version of P100, 95% pure exosome)

P100EZ - Ask for price

Breast cancer Exosome Isolation Kit

E601E002 20 tests
EUR 2500

EPCAM Capture Exosome Isolation Kit

E601E003 20 tests
EUR 2500

HSP70 Capture Exosome Isolation Kit

E601E007 20 tests
EUR 2500

Breast cancer Exosome Isolation Kit

MBS8579444-20Tests 20Tests
EUR 2625

Breast cancer Exosome Isolation Kit

MBS8579444-5x20Tests 5x20Tests
EUR 12240

EPCAM Capture Exosome Isolation Kit

MBS8579445-20Tests 20Tests
EUR 2625

EPCAM Capture Exosome Isolation Kit

MBS8579445-5x20Tests 5x20Tests
EUR 12240

HSP70 Capture Exosome Isolation Kit

MBS8579449-20Tests 20Tests
EUR 2625

HSP70 Capture Exosome Isolation Kit

MBS8579449-5x20Tests 5x20Tests
EUR 12240

ExoQualiTM Exosome Isolation Kit (Urine)

CEIK-003L-10T 10 T Ask for price

ExoQualiTM Exosome Isolation Kit (Urine)

CEIK-003L-30T 30 T Ask for price

ExoQualiTM Exosome Isolation Kit (Serum)

CEIK-005L-10T 10 T Ask for price

ExoQualiTM Exosome Isolation Kit (Serum)

CEIK-005L-30T 30 T Ask for price

ExoQualiTM Overall Exosome Isolation Immunoplates (from Cell Media)

CEIK-029L-96wells 96 wells Ask for price

ExoQualiTM Exosome Isolation Kit (Plasma)

CEIK-004L-10T 10 T Ask for price

ExoQualiTM Exosome Isolation Kit (Plasma)

CEIK-004L-30T 30 T Ask for price

Urine Exosome RNA Isolation Kit

47200 50 Preps
EUR 429

T-Pro Total Exosome Isolation reagent (from cell culture media)

JO66-V001M 500ml/BT
EUR 800

T-Pro Total Exosome Isolation reagent (from cell culture media)

JO66-V001S 100ml/BT
EUR 200

Exosome Isolation kit (for serum & plasma)

P101 10 rxn
EUR 199

Exosome Isolation kit (for serum & plasma)

P101L 40 rxn
EUR 769

Exosome Isolation kit (for serum & plasma)

P101S 2 rxn
EUR 69

Exosome Isolation kit (for serum & plasma -Exosome-RNA-NGS)

P101NGS - Ask for price

Exosome isolation Solution - Cell Media/ Urine (easy version of P100, 95% pure exosome) sample

P100EZ-sample - Ask for price

VEX Exosome Isolation Reagent (from serum)

R602 10 ml
EUR 769.2

ExoQualiTM Overall Exosome Isolation Reagent (from cell culture media)

CEIK-043L-10T 10 T Ask for price

ExoQualiTM Overall Exosome Isolation Reagent (from cell culture media)

CEIK-043L-24T 24 T Ask for price

Exosome Isolation kit (forHuman Body Fluid)

P121 10 rxn
EUR 199

Exosome Isolation kit (forHuman Body Fluid)

P121L 40 rxn
EUR 769

Exosome Isolation kit (forHuman Body Fluid)

P121S 2 rxn
EUR 69

VEX Exosome Isolation Reagent (from plasma)

R603 10 ml
EUR 769.2

ExoQualiTM Exosome Isolation Kit (Plasma & Serum)

CEIK-006L-10T 10 T Ask for price

ExoQualiTM Exosome Isolation Kit (Plasma & Serum)

CEIK-006L-30T 30 T Ask for price

ExoQualiTM Exosome Isolation Kit (All in one)

CEIK-008L-10T 10 T Ask for price

ExoQualiTM Exosome Isolation Kit (All in one)

CEIK-008L-30T 30 T Ask for price

EXO-Prep for exosome isolation from Urine

HBM-EXP-U25 30 ml (25 react)
EUR 234.36

ExoPure? Reagent (Overall Exosome Isolation, urine)

M1003-25 each
EUR 992.4

ExoPure? Reagent (Overall Exosome Isolation, urine)

M1003-50 each
EUR 1083.6

Cell Culture Media Exosome Purification and RNA Isolation Mini Kit

60700 50 Preps
EUR 611.4

Cell Culture Media Exosome Purification and RNA Isolation Midi Kit

60800 25 Preps
EUR 641.4

Cell Culture Media Exosome Purification and RNA Isolation Maxi Kit

60900 15 Preps
EUR 411

ExoQualiTM Exosome Isolation Kit (other body fluids)

CEIK-007L-10T 10 T Ask for price

ExoQualiTM Exosome Isolation Kit (other body fluids)

CEIK-007L-30T 30 T Ask for price

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 10 reactions)

M1030-10 each
EUR 1005.6

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 20 reactions)

M1030-20 each
EUR 1546.8

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions)

M1030-3 each
EUR 529.2

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 5 reactions)

M1030-5 each
EUR 796.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 10 reactions)

M1031-10 each
EUR 1005.6

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 20 reactions)

M1031-20 each
EUR 1546.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions)

M1031-3 each
EUR 523.2

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 5 reactions)

M1031-5 each
EUR 796.8

T-Pro Total Exosome Isolation reagent (from serum)

JO66-V002M 25ml/BT
EUR 800

T-Pro Total Exosome Isolation reagent (from serum)

JO66-V002S 1ml*5/set
EUR 200

Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome)

P101EZ - Ask for price

Easy-Exo® Saliva Exosome Isolation Kit, 95% pure

P530 20 rxn
EUR 399

Easy-Exo® Saliva Exosome Isolation Kit, 95% pure

P530S 2 rxn
EUR 169

ExoQualiTM Overall Exosome Isolation Reagent (from serum)

CEIK-044L-30T 30 T Ask for price

ExoQualiTM Overall Exosome Isolation Reagent (from serum)

CEIK-044L-50T 50 T Ask for price

ExoQualiTM Overall Exosome Isolation Reagent (from urine)

CEIK-046L-10T 10 T Ask for price

ExoQualiTM Overall Exosome Isolation Reagent (from urine)

CEIK-046L-24T 24 T Ask for price

ExoQualiTM Overall Exosome Isolation Reagent (from plasma)

CEIK-045L-30T 30 T Ask for price

ExoQualiTM Overall Exosome Isolation Reagent (from plasma)

CEIK-045L-50T 50 T Ask for price

EXO-Prep for exosome isolation from Plasma and serum

HBM-EXP-B5 5 ml
EUR 181.44

ExoPure? Reagent (Overall Exosome Isolation, biological fluids)

M1001-10 each
EUR 796.8

ExoPure? Reagent (Overall Exosome Isolation, biological fluids)

M1001-20 each
EUR 1260

ExoPure? Reagent (Overall Exosome Isolation, biological fluids)

M1001-5 each
EUR 633.6

ExoQualiTM Overall Exosome Isolation Immunoplates (from Serum)

CEIK-023L-96wells 96 wells Ask for price

ExoQualiTM Overall Exosome Isolation Immunoplates (from Saliva)

CEIK-026L-96wells 96 wells Ask for price

ExoQualiTM Overall Exosome Isolation Immunoplates (from Plasma)

CEIK-095L-96wells 96 wells Ask for price

 

Pleiotropic Results of Exosomes as a Remedy for Stroke Restoration

 

Stroke is the main reason behind incapacity, and stroke survivors endure from long-term sequelae even after receiving recombinant tissue plasminogen activator remedy and endovascular intracranial thrombectomy. Rising proof means that exosomes, nano-sized extracellular membrane vesicles, improve neurogenesis, angiogenesis, and axonal outgrowth, all of the whereas suppressing inflammatory reactions, thereby enhancing practical restoration after stroke.

A scientific literature assessment to check the affiliation of stroke restoration with exosome remedy was carried out, analyzing species, stroke mannequin, supply of exosomes, behavioral analyses, and consequence knowledge, in addition to molecular mechanisms.

13 research had been included within the current systematic assessment. Within the majority of research, exosomes derived from mesenchymal stromal cells or stem cells had been administered intravenously inside 24 h after transient center cerebral artery occlusion, displaying a big enchancment of neurological severity and motor features. Particular microRNAs and molecules had been recognized by mechanistic investigations, and their amplification was proven to additional improve therapeutic results, together with neurogenesis, angiogenesis, axonal outgrowth, and synaptogenesis.

General, this assessment addresses the present advances in exosome remedy for stroke restoration in preclinical research, which may hopefully be preparatory steps for the longer term improvement of medical trials involving stroke survivors to enhance practical outcomes.

 

Bone marrow mesenchymal stem cells-derived exosomes for penetrating and focused chemotherapy of pancreatic most cancers

 

Pancreatic ductal adenocarcinoma (PDAC) is among the most intractable malignancy, with an solely 6% 5-year relative survival price. The dismal therapeutic impact is attributed to the chemotherapy resistance and distinctive pathophysiology with ample inflammatory cytokines and irregular hyperplasia of extracellular matrix (ECM).

Primarily based on the idea that bone marrow mesenchymal stem cells (BM-MSCs) can affect the tumorous microenvironment and malignant progress of PDAC, we employed exosomes (Exos) derived from BM-MSCs as PDAC-homing automobiles to surpass the restrictions of pathological ECM and enhance the buildup of therapeutics in tumor web site. To beat chemoresistance of PDAC, paclitaxel (PTX) and gemcitabine monophosphate (GEMP)-an intermediate product of gemcitabine metabolism-were loaded in/on the purified Exos.

On this work, the Exo supply platform confirmed superiorities in homing and penetrating talents, which had been carried out on tumor spheroids and PDAC orthotopic fashions. In the meantime, the favorable anti-tumor efficacy in vivo and in vitro, plus comparatively delicate systemic toxicity, was discovered. Loading GEMP and PTX, benefitting from the naturally PDAC selectivity, the Exo platform we constructed performs mixed features on glorious penetrating, anti-matrix and overcoming chemoresistance (Scheme 1). Value expectantly, the Exo platform might present a potential method for focused therapies of PDAC.

Exosome Isolation kit (for cell culture media)

P100 10 rxn
EUR 199

Exosome Isolation kit (for cell culture media)

P100S 2 rxn
EUR 69

Exosome Isolation kit (for cell culture media)

P100L 40 rxn
EUR 1149

ExoQualiTM Exosome Isolation Kit (Stem Cell Media)

CEIK-002L-10T 10 T Ask for price

ExoQualiTM Exosome Isolation Kit (Stem Cell Media)

CEIK-002L-30T 30 T Ask for price

EXO-Prep for exosome isolation from Cell Media

HBM-EXP-C25 25 ml (25 react)
EUR 234.36

ExoPure? Reagent (Overall Exosome Isolation, cell media)

M1002-25 each
EUR 992.4

ExoPure? Reagent (Overall Exosome Isolation, cell media)

M1002-50 each
EUR 1083.6

Exosome Isolation kit (for stem cell culture media)

P107 10 rxn
EUR 199

Exosome Isolation kit (for stem cell culture media)

P107S 2 rxn
EUR 69

VEX Exosome Isolation Reagent (from cell culture media)

R601 50 ml
EUR 706.8

Exosome Isolation kit (for urine)

P120L 40 rxn
EUR 769

Exosome Isolation kit (for urine)

P120S 2 rxn
EUR 69

GPC1 Capture Exosome Isolation Kit

E601E004 20 tests
EUR 2500

CD63 Capture Exosome Isolation Kit

E601E005 20 tests
EUR 2500

CD81 Capture Exosome Isolation Kit

E601E006 20 tests
EUR 2500

GPC1 Capture Exosome Isolation Kit

MBS8579446-20Tests 20Tests
EUR 2625

GPC1 Capture Exosome Isolation Kit

MBS8579446-5x20Tests 5x20Tests
EUR 12240

CD63 Capture Exosome Isolation Kit

MBS8579447-20Tests 20Tests
EUR 2625

CD63 Capture Exosome Isolation Kit

MBS8579447-5x20Tests 5x20Tests
EUR 12240

CD81 Capture Exosome Isolation Kit

MBS8579448-20Tests 20Tests
EUR 2625

CD81 Capture Exosome Isolation Kit

MBS8579448-5x20Tests 5x20Tests
EUR 12240

Exosome isolation Solution - Cell Media/ Urine (easy version of P100, 95% pure exosome)

P100EZ - Ask for price

Breast cancer Exosome Isolation Kit

E601E002 20 tests
EUR 2500

EPCAM Capture Exosome Isolation Kit

E601E003 20 tests
EUR 2500

HSP70 Capture Exosome Isolation Kit

E601E007 20 tests
EUR 2500

Breast cancer Exosome Isolation Kit

MBS8579444-20Tests 20Tests
EUR 2625

Breast cancer Exosome Isolation Kit

MBS8579444-5x20Tests 5x20Tests
EUR 12240

EPCAM Capture Exosome Isolation Kit

MBS8579445-20Tests 20Tests
EUR 2625

EPCAM Capture Exosome Isolation Kit

MBS8579445-5x20Tests 5x20Tests
EUR 12240

HSP70 Capture Exosome Isolation Kit

MBS8579449-20Tests 20Tests
EUR 2625

HSP70 Capture Exosome Isolation Kit

MBS8579449-5x20Tests 5x20Tests
EUR 12240

ExoQualiTM Exosome Isolation Kit (Urine)

CEIK-003L-10T 10 T Ask for price

ExoQualiTM Exosome Isolation Kit (Urine)

CEIK-003L-30T 30 T Ask for price

ExoQualiTM Exosome Isolation Kit (Serum)

CEIK-005L-10T 10 T Ask for price

ExoQualiTM Exosome Isolation Kit (Serum)

CEIK-005L-30T 30 T Ask for price

ExoQualiTM Overall Exosome Isolation Immunoplates (from Cell Media)

CEIK-029L-96wells 96 wells Ask for price

ExoQualiTM Exosome Isolation Kit (Plasma)

CEIK-004L-10T 10 T Ask for price

ExoQualiTM Exosome Isolation Kit (Plasma)

CEIK-004L-30T 30 T Ask for price

Urine Exosome RNA Isolation Kit

47200 50 Preps
EUR 429

T-Pro Total Exosome Isolation reagent (from cell culture media)

JO66-V001M 500ml/BT
EUR 800

T-Pro Total Exosome Isolation reagent (from cell culture media)

JO66-V001S 100ml/BT
EUR 200

Exosome Isolation kit (for serum & plasma)

P101 10 rxn
EUR 199

Exosome Isolation kit (for serum & plasma)

P101L 40 rxn
EUR 769

Exosome Isolation kit (for serum & plasma)

P101S 2 rxn
EUR 69

Exosome Isolation kit (for serum & plasma -Exosome-RNA-NGS)

P101NGS - Ask for price

Exosome isolation Solution - Cell Media/ Urine (easy version of P100, 95% pure exosome) sample

P100EZ-sample - Ask for price

VEX Exosome Isolation Reagent (from serum)

R602 10 ml
EUR 769.2

ExoQualiTM Overall Exosome Isolation Reagent (from cell culture media)

CEIK-043L-10T 10 T Ask for price

ExoQualiTM Overall Exosome Isolation Reagent (from cell culture media)

CEIK-043L-24T 24 T Ask for price

Exosome Isolation kit (forHuman Body Fluid)

P121 10 rxn
EUR 199

Exosome Isolation kit (forHuman Body Fluid)

P121L 40 rxn
EUR 769

Exosome Isolation kit (forHuman Body Fluid)

P121S 2 rxn
EUR 69

VEX Exosome Isolation Reagent (from plasma)

R603 10 ml
EUR 769.2

ExoQualiTM Exosome Isolation Kit (Plasma & Serum)

CEIK-006L-10T 10 T Ask for price

ExoQualiTM Exosome Isolation Kit (Plasma & Serum)

CEIK-006L-30T 30 T Ask for price

ExoQualiTM Exosome Isolation Kit (All in one)

CEIK-008L-10T 10 T Ask for price

ExoQualiTM Exosome Isolation Kit (All in one)

CEIK-008L-30T 30 T Ask for price

EXO-Prep for exosome isolation from Urine

HBM-EXP-U25 30 ml (25 react)
EUR 234.36

ExoPure? Reagent (Overall Exosome Isolation, urine)

M1003-25 each
EUR 992.4

ExoPure? Reagent (Overall Exosome Isolation, urine)

M1003-50 each
EUR 1083.6

Cell Culture Media Exosome Purification and RNA Isolation Mini Kit

60700 50 Preps
EUR 611.4

Cell Culture Media Exosome Purification and RNA Isolation Midi Kit

60800 25 Preps
EUR 641.4

Cell Culture Media Exosome Purification and RNA Isolation Maxi Kit

60900 15 Preps
EUR 411

ExoQualiTM Exosome Isolation Kit (other body fluids)

CEIK-007L-10T 10 T Ask for price

ExoQualiTM Exosome Isolation Kit (other body fluids)

CEIK-007L-30T 30 T Ask for price

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 10 reactions)

M1030-10 each
EUR 1005.6

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 20 reactions)

M1030-20 each
EUR 1546.8

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions)

M1030-3 each
EUR 529.2

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 5 reactions)

M1030-5 each
EUR 796.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 10 reactions)

M1031-10 each
EUR 1005.6

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 20 reactions)

M1031-20 each
EUR 1546.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions)

M1031-3 each
EUR 523.2

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 5 reactions)

M1031-5 each
EUR 796.8

T-Pro Total Exosome Isolation reagent (from serum)

JO66-V002M 25ml/BT
EUR 800

T-Pro Total Exosome Isolation reagent (from serum)

JO66-V002S 1ml*5/set
EUR 200

Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome)

P101EZ - Ask for price

Easy-Exo® Saliva Exosome Isolation Kit, 95% pure

P530 20 rxn
EUR 399

Easy-Exo® Saliva Exosome Isolation Kit, 95% pure

P530S 2 rxn
EUR 169

ExoQualiTM Overall Exosome Isolation Reagent (from serum)

CEIK-044L-30T 30 T Ask for price

ExoQualiTM Overall Exosome Isolation Reagent (from serum)

CEIK-044L-50T 50 T Ask for price

ExoQualiTM Overall Exosome Isolation Reagent (from urine)

CEIK-046L-10T 10 T Ask for price

ExoQualiTM Overall Exosome Isolation Reagent (from urine)

CEIK-046L-24T 24 T Ask for price

ExoQualiTM Overall Exosome Isolation Reagent (from plasma)

CEIK-045L-30T 30 T Ask for price

ExoQualiTM Overall Exosome Isolation Reagent (from plasma)

CEIK-045L-50T 50 T Ask for price

EXO-Prep for exosome isolation from Plasma and serum

HBM-EXP-B5 5 ml
EUR 181.44

ExoPure? Reagent (Overall Exosome Isolation, biological fluids)

M1001-10 each
EUR 796.8

ExoPure? Reagent (Overall Exosome Isolation, biological fluids)

M1001-20 each
EUR 1260

ExoPure? Reagent (Overall Exosome Isolation, biological fluids)

M1001-5 each
EUR 633.6

ExoQualiTM Overall Exosome Isolation Immunoplates (from Serum)

CEIK-023L-96wells 96 wells Ask for price

ExoQualiTM Overall Exosome Isolation Immunoplates (from Saliva)

CEIK-026L-96wells 96 wells Ask for price

ExoQualiTM Overall Exosome Isolation Immunoplates (from Plasma)

CEIK-095L-96wells 96 wells Ask for price

ExoQualiTM Overall Exosome Isolation Immunoplates (from Urine)

CEIK-096L-96wells 96 wells Ask for price

EXTRAClean Cell Culture Media Exosome Purification and RNA Isolation Mini Kit

73300 50 Preps
EUR 763.8

EXTRAClean Cell Culture Media Exosome Purification and RNA Isolation Midi Kit

73310 25 Preps
EUR 801

EXTRAClean Cell Culture Media Exosome Purification and RNA Isolation Maxi Kit

73320 15 Preps
EUR 513

Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome) sample

P101EZ--sample - Ask for price

ExoQuick-LP for lipoprotein pre-clear & exosome isolation

EXOLP5A-1 5 reactions
EUR 473

ExoQuick-CG cGMP-grade Exosome Isolation reagent (50 ml)

EXOCG50A-1 50 ml
EUR 1106

Reagent for Total Exosome Isolation (Culture Media Supplement)

EIR-02 50 ml
EUR 2485.2
Description: This product is used for isolating exosomes from culture media supplement based on chemical precipitation isolation method.

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 10 reactions)

M1036-10 each
EUR 1005.6

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 20 reactions)

M1036-20 each
EUR 1546.8

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 3 reactions)

M1036-3 each
EUR 516

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 5 reactions)

M1036-5 each
EUR 777.6

MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 10 reactions)

M1037-10 each
EUR 1005.6

MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 20 reactions)

M1037-20 each
EUR 1546.8

MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 3 reactions)

M1037-3 each
EUR 516

MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 5 reactions)

M1037-5 each
EUR 777.6

Urine Exosome Purification and RNA Isolation Mini Kit

58400 50 Preps
EUR 843

Urine Exosome Purification and RNA Isolation Midi Kit

58700 25 Preps
EUR 797.4

Urine Exosome Purification and RNA Isolation Maxi Kit

58800 15 Preps
EUR 479.4

TumorExoPure? Immunoplates (Exosome Isolation, plasma, colorimetric assay)

M1016-100-T each
EUR 874.8

TumorExoPure? Immunoplates (Exosome Isolation, plasma, luminometric assay)

M1017-100-W each
EUR 888

TumorExoPure? Immunoplates (Exosome Isolation, plasma, fluorimetric assay)

M1018-100-B each
EUR 888

GlialExoPure? Immunoplates (Exosome Isolation, plasma, colorimetric assay)

M1022-100-T each
EUR 888

GlialExoPure? Immunoplates (Exosome Isolation, plasma, luminometric assay)

M1023-100-W each
EUR 888

GlialExoPure? Immunoplates (Exosome Isolation, plasma, fluorimetric assay)

M1024-100-B each
EUR 888

ExoQualiTM Overall Exosome Isolation Reagent (from other body fluids)

CEIK-047L-10T 10 T Ask for price

ExoQualiTM Overall Exosome Isolation Reagent (from other body fluids)

CEIK-047L-24T 24 T Ask for price

NeuralExoPure? Immunoplates (Exosome Isolation, plasma, colorimetric assay)

M1019-100-T each
EUR 907.2

NeuralExoPure? Immunoplates (Exosome Isolation, plasma, luminometric assay)

M1020-100-W each
EUR 888

NeuralExoPure? Immunoplates (Exosome Isolation, plasma, fluorimetric assay)

M1021-100-B each
EUR 888

MinuteTM Hi-Efficiency Exosome Isolation Reagent (20 ml) (Non-PEG)

EI-027 each
EUR 345

ExoPure? Immunoplates (Overall Exosome Isolation, serum, colorimetric assay)

M1007-100-T each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, serum, luminometric assay)

M1008-100-W each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, serum, fluorimetric assay)

M1009-100-B each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, colorimetric assay)

M1010-100-T each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, luminometric assay)

M1011-100-W each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, fluorimetric assay)

M1012-100-B each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, colorimetric assay)

M1013-100-T each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, luminometric assay)

M1014-100-W each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, fluorimetric assay)

M1015-100-B each
EUR 888

Urine Exosome and Free-Circulating RNA Isolation Mini Kit

59200 50 Preps
EUR 941.4

Urine Exosome and Free-Circulating RNA Isolation Midi Kit

59300 25 Preps
EUR 843

Urine Exosome and Free-Circulating RNA Isolation Maxi Kit

59400 15 Preps
EUR 641.4

Plasma/Serum Exosome Purification and RNA Isolation Mini Kit

58300 50 Preps
EUR 627

Plasma/Serum Exosome Purification and RNA Isolation Midi Kit

58500 25 Preps
EUR 569.4

Plasma/Serum Exosome Purification and RNA Isolation Maxi Kit

58600 15 Preps
EUR 341.4

Exosome Isolation Kit for Cell Culture Supernatant,Serum,Plasma,Breast Milk,Urine,Saliva,Yeast, Plant

CSB-EI0102 2T
EUR 340
Description: Exosomes are a type of extracellular vesicles secreted by cells that contain a variety of RNA, proteins, and phospholipids with a diameter of about 30-150 nm. Exosomes play an important role in the transfer of material and information between cells.This exosome isolation kit provides a simple and reliable method to extract intact exosomes from the cell supernatant. Comparing with other well-known brand kits, cell supernatant exosome isolation kit provided by CUSABIO has its own features. It is suitable for the isolation of exosomes from the supernatant of a variety of cells. And the exosomes isolated by this kit are comparable to ultracentrifugation with High Purity and High Yield. Moreover, this kit is simple to use and no equipment requirement.Exosomal vesicles isolated by this product are suitable for various downstream applications, such as electron microscopy analysis, NTA analysis, NanoFCM analysis, Western Blot, fluorescence quantitative (qPCR), and high-throughput sequencing, etc.

Exosome Isolation Kit for Cell Culture Supernatant,Serum,Plasma,Breast Milk,Urine,Saliva,Yeast, Plant

CSB-EI0110 10T
EUR 1050
Description: Exosomes are a type of extracellular vesicles secreted by cells that contain a variety of RNA, proteins, and phospholipids with a diameter of about 30-150 nm. Exosomes play an important role in the transfer of material and information between cells.This exosome isolation kit provides a simple and reliable method to extract intact exosomes from the cell supernatant. Comparing with other well-known brand kits, cell supernatant exosome isolation kit provided by CUSABIO has its own features. It is suitable for the isolation of exosomes from the supernatant of a variety of cells. And the exosomes isolated by this kit are comparable to ultracentrifugation with High Purity and High Yield. Moreover, this kit is simple to use and no equipment requirement.Exosomal vesicles isolated by this product are suitable for various downstream applications, such as electron microscopy analysis, NTA analysis, NanoFCM analysis, Western Blot, fluorescence quantitative (qPCR), and high-throughput sequencing, etc.

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum)

M1038-10 each
EUR 1005.6

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum)

M1038-20 each
EUR 1546.8

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum)

M1038-3 each
EUR 523.2

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum)

M1038-5 each
EUR 796.8

ExoQuick Exosome Isolation and RNA Purification kit (for Serum and Plasma)

EQ806A-1 20 preps
EUR 493

EXTRAClean Urine Exosome Purification and RNA Isolation Midi Kit

73200 25 Preps
EUR 996.6

EXTRAClean Urine Exosome Purification and RNA Isolation Mini Kit

73210 50 Preps
EUR 1053

EXTRAClean Urine Exosome Purification and RNA Isolation Maxi Kit

73220 15 Preps
EUR 599.4

MinuteTM Hi-Efficiency Saliva Exosome Isolation Kit (50 Tests) (Non-PEG)

SE-030 each
EUR 330

Monocytes/PlateletExoPure? Immunoplates (Exosome Isolation, plasma, colorimetric assay)

M1025-100-T each
EUR 888

Monocytes/PlateletExoPure? Immunoplates (Exosome Isolation, plasma, luminometric assay)

M1026-100-W each
EUR 888

Monocytes/PlateletExoPure? Immunoplates (Exosome Isolation, plasma, fluorimetric assay)

M1027-100-B each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, plasma, urine, colorimetric assay)

M1004-100-T each
EUR 1136.4

ExoPure? Immunoplates (Overall Exosome Isolation, plasma, urine, luminometric assay)

M1005-100-W each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, plasma, urine, fluorometric assay)

M1006-100-B each
EUR 888

CytoSelect Clonogenic Tumor Cell Isolation Kit (5 preps)

CBA-155 5 preps
EUR 957.6
Description: Many solid tumors contain heterogeneous populations of normal and cancerous cells. Separation of these cell populations is key to an accurate assessment of the true genotypic and phenotypic differences between normal and tumor cells. Our CytoSelect Clonogenic Tumor Cell Isolation Kit uses a proprietary semisolid agar medium to facilitate formation of colonies by cells from solid tumors. Colonies are grown in either a 6-well plate or a 35mm culture dish. These colonies are isolated away from single (i.e. normal) cells by size filtration. The viable cells from these colonies can be easily recovered for further analysis.

XCF COMPLETE Exosome and cfDNA Isolation Kit (for Serum and Plasma)

XCF100A-1 20 rxn
EUR 583

ExoQuick Exosome Isolation and RNA Purification kit (for Tissue Culture Media)

EQ806TC-1 10 preps
EUR 493

Plasma/Serum Exosome and Free-Circulating RNA Isolation Mini Kit

59500 50 Preps
EUR 797.4

Plasma/Serum Exosome and Free-Circulating RNA Isolation Midi Kit

59600 25 Preps
EUR 683.4

 

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