Pre-incubation with human umbilical twine derived mesenchymal stem cells-exosomes prevents cisplatin-induced renal tubular epithelial cell harm
Objective: The administration of cisplatin is proscribed as a result of its nephrotoxicity, and prevention of this nephrotoxicity of cisplatin is troublesome. Mesenchymal stem cell (MSC)-derived exosomes have been implicated as a novel therapeutic method for tissue harm.
Outcomes: In vitro, the NRK cells pre-incubated with HUMSC-exosomes elevated the Cp-inhibited cell viability, proliferation exercise, and the cell proportion in G1-phase and inhibited Cp-induced cell apoptosis. Moreover, the expression ranges of apoptotic marker proteins Bim, Dangerous, Bax, cleaved caspase-3, and cleaved caspase-9 induced by Cp within the NRK cells had been decreased by pre-incubating with HUMSC-exosomes.
Conclusion: Our findings indicated that the exosomes from HUMSCs can successfully enhance the survival price and inhibit cell apoptosis of NRK cells. Subsequently, pre-treatment of HUMSC-exosomes could also be a brand new methodology to enhance the therapeutic impact of cisplatin.
Sufferers and strategies: Exosomes had been remoted from human umbilical twine derived mesenchymal stem cells (HUMSCs). Co-culture of regular rat renal tubular epithelial cells (NRK) and the absorption of exogenous exosomes by NRK cells had been examined in vitro. Then the NRK cells had been incubated with exosomes from HUMSCs and cisplatin (Cp). Cells had been harvested for MTT assay, cloning formation, circulate cytometry, and Western blot.
ataxin
Exosome Isolation kit (for serum & plasma) |
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| P101 | 101Bio | - | Ask for price |
Exosome Isolation kit (for serum & plasma) |
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| P101L | 101Bio | - | Ask for price |
Exosome Isolation kit (for serum & plasma) |
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| P101S | 101Bio | - | Ask for price |
Exosome Isolation kit (for serum & plasma -Exosome-RNA-NGS) |
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| P101NGS | 101Bio | - | Ask for price |
Exosome isolation Solution - Cell Media/ Urine (easy version of P100, 95% pure exosome) |
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| P100EZ | 101Bio | - | Ask for price |
VEX Exosome Isolation Reagent (from serum) |
|||
| R602 | Vazyme | 10 ml | EUR 769.2 |
Exosome Isolation kit (forHuman Body Fluid) |
|||
| P121 | 101Bio | - | Ask for price |
Exosome Isolation kit (forHuman Body Fluid) |
|||
| P121L | 101Bio | - | Ask for price |
Exosome Isolation kit (forHuman Body Fluid) |
|||
| P121S | 101Bio | - | Ask for price |
VEX Exosome Isolation Reagent (from plasma) |
|||
| R603 | Vazyme | 10 ml | EUR 769.2 |
Exosome isolation Solution - Cell Media/ Urine (easy version of P100, 95% pure exosome) sample |
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| P100EZ-sample | 101Bio | - | Ask for price |
ExoPure? Reagent (Overall Exosome Isolation, urine) |
|||
| M1003-25 | Biovision | each | EUR 992.4 |
ExoPure? Reagent (Overall Exosome Isolation, urine) |
|||
| M1003-50 | Biovision | each | EUR 1083.6 |
Easy-Exo Saliva Exosome Isolation Kit, 95% pure |
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| P530 | 101Bio | - | Ask for price |
Easy-Exo Saliva Exosome Isolation Kit, 95% pure |
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| P530S | 101Bio | - | Ask for price |
Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome) |
|||
| P101EZ | 101Bio | - | Ask for price |
ExoPure? Reagent (Overall Exosome Isolation, biological fluids) |
|||
| M1001-10 | Biovision | each | EUR 796.8 |
ExoPure? Reagent (Overall Exosome Isolation, biological fluids) |
|||
| M1001-20 | Biovision | each | EUR 1260 |
ExoPure? Reagent (Overall Exosome Isolation, biological fluids) |
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| M1001-5 | Biovision | each | EUR 633.6 |
ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 10 reactions) |
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| M1030-10 | Biovision | each | EUR 1005.6 |
ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 20 reactions) |
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| M1030-20 | Biovision | each | EUR 1546.8 |
ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions) |
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| M1030-3 | Biovision | each | EUR 529.2 |
ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 5 reactions) |
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| M1030-5 | Biovision | each | EUR 796.8 |
ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 10 reactions) |
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| M1031-10 | Biovision | each | EUR 1005.6 |
ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 20 reactions) |
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| M1031-20 | Biovision | each | EUR 1546.8 |
ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions) |
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| M1031-3 | Biovision | each | EUR 523.2 |
ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 5 reactions) |
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| M1031-5 | Biovision | each | EUR 796.8 |
Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome) sample |
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| P101EZ--sample | 101Bio | - | Ask for price |
ExoQuick-CG cGMP-grade Exosome Isolation reagent (50 ml) |
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| EXOCG50A-1 | SBI | 50 ml | EUR 1106 |
ExoQuick-LP for lipoprotein pre-clear & exosome isolation |
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| EXOLP5A-1 | SBI | 5 reactions | EUR 473 |
Reagent for Total Exosome Isolation (Culture Media Supplement) |
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| EIR-02 | Creative Biolabs | 50 ml | EUR 2485.2 |
|
Description: This product is used for isolating exosomes from culture media supplement based on chemical precipitation isolation method. |
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TumorExoPure? Immunoplates (Exosome Isolation, plasma, colorimetric assay) |
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| M1016-100-T | Biovision | each | EUR 874.8 |
TumorExoPure? Immunoplates (Exosome Isolation, plasma, luminometric assay) |
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| M1017-100-W | Biovision | each | EUR 888 |
TumorExoPure? Immunoplates (Exosome Isolation, plasma, fluorimetric assay) |
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| M1018-100-B | Biovision | each | EUR 888 |
GlialExoPure? Immunoplates (Exosome Isolation, plasma, colorimetric assay) |
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| M1022-100-T | Biovision | each | EUR 888 |
GlialExoPure? Immunoplates (Exosome Isolation, plasma, luminometric assay) |
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| M1023-100-W | Biovision | each | EUR 888 |
GlialExoPure? Immunoplates (Exosome Isolation, plasma, fluorimetric assay) |
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| M1024-100-B | Biovision | each | EUR 888 |
NeuralExoPure? Immunoplates (Exosome Isolation, plasma, colorimetric assay) |
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| M1019-100-T | Biovision | each | EUR 907.2 |
NeuralExoPure? Immunoplates (Exosome Isolation, plasma, luminometric assay) |
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| M1020-100-W | Biovision | each | EUR 888 |
NeuralExoPure? Immunoplates (Exosome Isolation, plasma, fluorimetric assay) |
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| M1021-100-B | Biovision | each | EUR 888 |
MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 10 reactions) |
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| M1036-10 | Biovision | each | EUR 1005.6 |
MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 20 reactions) |
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| M1036-20 | Biovision | each | EUR 1546.8 |
MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 3 reactions) |
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| M1036-3 | Biovision | each | EUR 516 |
MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 5 reactions) |
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| M1036-5 | Biovision | each | EUR 777.6 |
MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 10 reactions) |
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| M1037-10 | Biovision | each | EUR 1005.6 |
MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 20 reactions) |
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| M1037-20 | Biovision | each | EUR 1546.8 |
MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 3 reactions) |
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| M1037-3 | Biovision | each | EUR 516 |
MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 5 reactions) |
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| M1037-5 | Biovision | each | EUR 777.6 |
ExoPure? Immunoplates (Overall Exosome Isolation, serum, colorimetric assay) |
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| M1007-100-T | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, serum, luminometric assay) |
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| M1008-100-W | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, serum, fluorimetric assay) |
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| M1009-100-B | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, saliva, colorimetric assay) |
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| M1010-100-T | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, saliva, luminometric assay) |
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| M1011-100-W | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, saliva, fluorimetric assay) |
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| M1012-100-B | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, saliva, colorimetric assay) |
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| M1013-100-T | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, saliva, luminometric assay) |
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| M1014-100-W | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, saliva, fluorimetric assay) |
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| M1015-100-B | Biovision | each | EUR 888 |
ExoQuick Exosome Isolation and RNA Purification kit (for Serum and Plasma) |
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| EQ806A-1 | SBI | 20 preps | EUR 493 |
ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum) |
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| M1038-10 | Biovision | each | EUR 1005.6 |
ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum) |
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| M1038-20 | Biovision | each | EUR 1546.8 |
ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum) |
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| M1038-3 | Biovision | each | EUR 523.2 |
ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum) |
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| M1038-5 | Biovision | each | EUR 796.8 |
XCF COMPLETE Exosome and cfDNA Isolation Kit (for Serum and Plasma) |
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| XCF100A-1 | SBI | 20 rxn | EUR 583 |
ExoQuick Exosome Isolation and RNA Purification kit (for Tissue Culture Media) |
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| EQ806TC-1 | SBI | 10 preps | EUR 493 |
ExoPure? Immunoplates (Overall Exosome Isolation, plasma, urine, colorimetric assay) |
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| M1004-100-T | Biovision | each | EUR 1136.4 |
ExoPure? Immunoplates (Overall Exosome Isolation, plasma, urine, luminometric assay) |
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| M1005-100-W | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, plasma, urine, fluorometric assay) |
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| M1006-100-B | Biovision | each | EUR 888 |
Monocytes/PlateletExoPure? Immunoplates (Exosome Isolation, plasma, colorimetric assay) |
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| M1025-100-T | Biovision | each | EUR 888 |
Monocytes/PlateletExoPure? Immunoplates (Exosome Isolation, plasma, luminometric assay) |
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| M1026-100-W | Biovision | each | EUR 888 |
Monocytes/PlateletExoPure? Immunoplates (Exosome Isolation, plasma, fluorimetric assay) |
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| M1027-100-B | Biovision | each | EUR 888 |
ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 10 reactions) |
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| M1039-10 | Biovision | each | EUR 1005.6 |
ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 20 reactions) |
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| M1039-20 | Biovision | each | EUR 1546.8 |
ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 3 reactions) |
|||
| M1039-3 | Biovision | each | EUR 523.2 |
ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 5 reactions) |
|||
| M1039-5 | Biovision | each | EUR 796.8 |
TumorExoPure? 0.4 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 10 reactions) |
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| M1032-10 | Biovision | each | EUR 1057.2 |
TumorExoPure? 0.4 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 20 reactions) |
|||
| M1032-20 | Biovision | each | EUR 1618.8 |
TumorExoPure? 0.4 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 3 reactions) |
|||
| M1032-3 | Biovision | each | EUR 523.2 |
TumorExoPure? 0.4 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 5 reactions) |
|||
| M1032-5 | Biovision | each | EUR 796.8 |
TumorExoPure? 1.0 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 10 reactions) |
|||
| M1033-10 | Biovision | each | EUR 1057.2 |
TumorExoPure? 1.0 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 20 reactions) |
|||
| M1033-20 | Biovision | each | EUR 1618.8 |
TumorExoPure? 1.0 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 3 reactions) |
|||
| M1033-3 | Biovision | each | EUR 523.2 |
TumorExoPure? 1.0 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 5 reactions) |
|||
| M1033-5 | Biovision | each | EUR 796.8 |
MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 10 reactions) |
|||
| M1034-10 | Biovision | each | EUR 1005.6 |
MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 20 reactions) |
|||
| M1034-20 | Biovision | each | EUR 1495.2 |
MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 3 reactions) |
|||
| M1034-3 | Biovision | each | EUR 398.4 |
MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 5 reactions) |
|||
| M1034-5 | Biovision | each | EUR 777.6 |
MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 10 reactions) |
|||
| M1035-10 | Biovision | each | EUR 1005.6 |
MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 20 reactions) |
|||
| M1035-20 | Biovision | each | EUR 1495.2 |
MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 3 reactions) |
|||
| M1035-3 | Biovision | each | EUR 516 |
MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 5 reactions) |
|||
| M1035-5 | Biovision | each | EUR 777.6 |
Pleiotropic Results of Exosomes as a Remedy for Stroke Restoration
Stroke is the main reason behind incapacity, and stroke survivors endure from long-term sequelae even after receiving recombinant tissue plasminogen activator remedy and endovascular intracranial thrombectomy. Rising proof means that exosomes, nano-sized extracellular membrane vesicles, improve neurogenesis, angiogenesis, and axonal outgrowth, all of the whereas suppressing inflammatory reactions, thereby enhancing practical restoration after stroke.
A scientific literature assessment to check the affiliation of stroke restoration with exosome remedy was carried out, analyzing species, stroke mannequin, supply of exosomes, behavioral analyses, and consequence knowledge, in addition to molecular mechanisms.
13 research had been included within the current systematic assessment. Within the majority of research, exosomes derived from mesenchymal stromal cells or stem cells had been administered intravenously inside 24 h after transient center cerebral artery occlusion, displaying a big enchancment of neurological severity and motor features. Particular microRNAs and molecules had been recognized by mechanistic investigations, and their amplification was proven to additional improve therapeutic results, together with neurogenesis, angiogenesis, axonal outgrowth, and synaptogenesis.
General, this assessment addresses the present advances in exosome remedy for stroke restoration in preclinical research, which may hopefully be preparatory steps for the longer term improvement of medical trials involving stroke survivors to enhance practical outcomes.
Bone marrow mesenchymal stem cells-derived exosomes for penetrating and focused chemotherapy of pancreatic most cancers
Pancreatic ductal adenocarcinoma (PDAC) is among the most intractable malignancy, with an solely 6% 5-year relative survival price. The dismal therapeutic impact is attributed to the chemotherapy resistance and distinctive pathophysiology with ample inflammatory cytokines and irregular hyperplasia of extracellular matrix (ECM).
Primarily based on the idea that bone marrow mesenchymal stem cells (BM-MSCs) can affect the tumorous microenvironment and malignant progress of PDAC, we employed exosomes (Exos) derived from BM-MSCs as PDAC-homing automobiles to surpass the restrictions of pathological ECM and enhance the buildup of therapeutics in tumor web site. To beat chemoresistance of PDAC, paclitaxel (PTX) and gemcitabine monophosphate (GEMP)-an intermediate product of gemcitabine metabolism-were loaded in/on the purified Exos.
On this work, the Exo supply platform confirmed superiorities in homing and penetrating talents, which had been carried out on tumor spheroids and PDAC orthotopic fashions. In the meantime, the favorable anti-tumor efficacy in vivo and in vitro, plus comparatively delicate systemic toxicity, was discovered. Loading GEMP and PTX, benefitting from the naturally PDAC selectivity, the Exo platform we constructed performs mixed features on glorious penetrating, anti-matrix and overcoming chemoresistance (Scheme 1). Value expectantly, the Exo platform might present a potential method for focused therapies of PDAC.
ExoPure? Reagent (Overall Exosome Isolation, cell media) |
|||
| M1002-50 | Biovision | each | EUR 1083.6 |
VEX Exosome Isolation Reagent (from cell culture media) |
|||
| R601 | Vazyme | 50 ml | EUR 706.8 |
Exosome Isolation kit (for serum & plasma) |
|||
| P101 | 101Bio | - | Ask for price |
Exosome Isolation kit (for serum & plasma) |
|||
| P101L | 101Bio | - | Ask for price |
Exosome Isolation kit (for serum & plasma) |
|||
| P101S | 101Bio | - | Ask for price |
Exosome Isolation kit (for serum & plasma -Exosome-RNA-NGS) |
|||
| P101NGS | 101Bio | - | Ask for price |
Exosome isolation Solution - Cell Media/ Urine (easy version of P100, 95% pure exosome) |
|||
| P100EZ | 101Bio | - | Ask for price |
VEX Exosome Isolation Reagent (from serum) |
|||
| R602 | Vazyme | 10 ml | EUR 769.2 |
Exosome Isolation kit (forHuman Body Fluid) |
|||
| P121 | 101Bio | - | Ask for price |
Exosome Isolation kit (forHuman Body Fluid) |
|||
| P121L | 101Bio | - | Ask for price |
Exosome Isolation kit (forHuman Body Fluid) |
|||
| P121S | 101Bio | - | Ask for price |
VEX Exosome Isolation Reagent (from plasma) |
|||
| R603 | Vazyme | 10 ml | EUR 769.2 |
Exosome isolation Solution - Cell Media/ Urine (easy version of P100, 95% pure exosome) sample |
|||
| P100EZ-sample | 101Bio | - | Ask for price |
ExoPure? Reagent (Overall Exosome Isolation, urine) |
|||
| M1003-25 | Biovision | each | EUR 992.4 |
ExoPure? Reagent (Overall Exosome Isolation, urine) |
|||
| M1003-50 | Biovision | each | EUR 1083.6 |
Easy-Exo Saliva Exosome Isolation Kit, 95% pure |
|||
| P530 | 101Bio | - | Ask for price |
Easy-Exo Saliva Exosome Isolation Kit, 95% pure |
|||
| P530S | 101Bio | - | Ask for price |
Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome) |
|||
| P101EZ | 101Bio | - | Ask for price |
ExoPure? Reagent (Overall Exosome Isolation, biological fluids) |
|||
| M1001-10 | Biovision | each | EUR 796.8 |
ExoPure? Reagent (Overall Exosome Isolation, biological fluids) |
|||
| M1001-20 | Biovision | each | EUR 1260 |
ExoPure? Reagent (Overall Exosome Isolation, biological fluids) |
|||
| M1001-5 | Biovision | each | EUR 633.6 |
ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 10 reactions) |
|||
| M1030-10 | Biovision | each | EUR 1005.6 |
ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 20 reactions) |
|||
| M1030-20 | Biovision | each | EUR 1546.8 |
ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions) |
|||
| M1030-3 | Biovision | each | EUR 529.2 |
ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 5 reactions) |
|||
| M1030-5 | Biovision | each | EUR 796.8 |
ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 10 reactions) |
|||
| M1031-10 | Biovision | each | EUR 1005.6 |
ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 20 reactions) |
|||
| M1031-20 | Biovision | each | EUR 1546.8 |
ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions) |
|||
| M1031-3 | Biovision | each | EUR 523.2 |
ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 5 reactions) |
|||
| M1031-5 | Biovision | each | EUR 796.8 |
Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome) sample |
|||
| P101EZ--sample | 101Bio | - | Ask for price |
ExoQuick-CG cGMP-grade Exosome Isolation reagent (50 ml) |
|||
| EXOCG50A-1 | SBI | 50 ml | EUR 1106 |
ExoQuick-LP for lipoprotein pre-clear & exosome isolation |
|||
| EXOLP5A-1 | SBI | 5 reactions | EUR 473 |
Reagent for Total Exosome Isolation (Culture Media Supplement) |
|||
| EIR-02 | Creative Biolabs | 50 ml | EUR 2485.2 |
|
Description: This product is used for isolating exosomes from culture media supplement based on chemical precipitation isolation method. |
|||
TumorExoPure? Immunoplates (Exosome Isolation, plasma, colorimetric assay) |
|||
| M1016-100-T | Biovision | each | EUR 874.8 |
TumorExoPure? Immunoplates (Exosome Isolation, plasma, luminometric assay) |
|||
| M1017-100-W | Biovision | each | EUR 888 |
TumorExoPure? Immunoplates (Exosome Isolation, plasma, fluorimetric assay) |
|||
| M1018-100-B | Biovision | each | EUR 888 |
GlialExoPure? Immunoplates (Exosome Isolation, plasma, colorimetric assay) |
|||
| M1022-100-T | Biovision | each | EUR 888 |
GlialExoPure? Immunoplates (Exosome Isolation, plasma, luminometric assay) |
|||
| M1023-100-W | Biovision | each | EUR 888 |
GlialExoPure? Immunoplates (Exosome Isolation, plasma, fluorimetric assay) |
|||
| M1024-100-B | Biovision | each | EUR 888 |
NeuralExoPure? Immunoplates (Exosome Isolation, plasma, colorimetric assay) |
|||
| M1019-100-T | Biovision | each | EUR 907.2 |
NeuralExoPure? Immunoplates (Exosome Isolation, plasma, luminometric assay) |
|||
| M1020-100-W | Biovision | each | EUR 888 |
NeuralExoPure? Immunoplates (Exosome Isolation, plasma, fluorimetric assay) |
|||
| M1021-100-B | Biovision | each | EUR 888 |
MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 10 reactions) |
|||
| M1036-10 | Biovision | each | EUR 1005.6 |
MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 20 reactions) |
|||
| M1036-20 | Biovision | each | EUR 1546.8 |
MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 3 reactions) |
|||
| M1036-3 | Biovision | each | EUR 516 |
MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 5 reactions) |
|||
| M1036-5 | Biovision | each | EUR 777.6 |
MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 10 reactions) |
|||
| M1037-10 | Biovision | each | EUR 1005.6 |
MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 20 reactions) |
|||
| M1037-20 | Biovision | each | EUR 1546.8 |
MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 3 reactions) |
|||
| M1037-3 | Biovision | each | EUR 516 |
MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 5 reactions) |
|||
| M1037-5 | Biovision | each | EUR 777.6 |
ExoPure? Immunoplates (Overall Exosome Isolation, serum, colorimetric assay) |
|||
| M1007-100-T | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, serum, luminometric assay) |
|||
| M1008-100-W | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, serum, fluorimetric assay) |
|||
| M1009-100-B | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, saliva, colorimetric assay) |
|||
| M1010-100-T | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, saliva, luminometric assay) |
|||
| M1011-100-W | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, saliva, fluorimetric assay) |
|||
| M1012-100-B | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, saliva, colorimetric assay) |
|||
| M1013-100-T | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, saliva, luminometric assay) |
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| M1014-100-W | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, saliva, fluorimetric assay) |
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| M1015-100-B | Biovision | each | EUR 888 |
ExoQuick Exosome Isolation and RNA Purification kit (for Serum and Plasma) |
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| EQ806A-1 | SBI | 20 preps | EUR 493 |
ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum) |
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| M1038-10 | Biovision | each | EUR 1005.6 |
ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum) |
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| M1038-20 | Biovision | each | EUR 1546.8 |
ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum) |
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| M1038-3 | Biovision | each | EUR 523.2 |
ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum) |
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| M1038-5 | Biovision | each | EUR 796.8 |
XCF COMPLETE Exosome and cfDNA Isolation Kit (for Serum and Plasma) |
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| XCF100A-1 | SBI | 20 rxn | EUR 583 |
ExoQuick Exosome Isolation and RNA Purification kit (for Tissue Culture Media) |
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| EQ806TC-1 | SBI | 10 preps | EUR 493 |
ExoPure? Immunoplates (Overall Exosome Isolation, plasma, urine, colorimetric assay) |
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| M1004-100-T | Biovision | each | EUR 1136.4 |
ExoPure? Immunoplates (Overall Exosome Isolation, plasma, urine, luminometric assay) |
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| M1005-100-W | Biovision | each | EUR 888 |
ExoPure? Immunoplates (Overall Exosome Isolation, plasma, urine, fluorometric assay) |
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| M1006-100-B | Biovision | each | EUR 888 |
Monocytes/PlateletExoPure? Immunoplates (Exosome Isolation, plasma, colorimetric assay) |
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| M1025-100-T | Biovision | each | EUR 888 |
Monocytes/PlateletExoPure? Immunoplates (Exosome Isolation, plasma, luminometric assay) |
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| M1026-100-W | Biovision | each | EUR 888 |
Monocytes/PlateletExoPure? Immunoplates (Exosome Isolation, plasma, fluorimetric assay) |
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| M1027-100-B | Biovision | each | EUR 888 |
Crohn's Disease Exosome |
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| P141-CR | 101Bio | - | Ask for price |
ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 10 reactions) |
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| M1039-10 | Biovision | each | EUR 1005.6 |
ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 20 reactions) |
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| M1039-20 | Biovision | each | EUR 1546.8 |
ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 3 reactions) |
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| M1039-3 | Biovision | each | EUR 523.2 |
ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 5 reactions) |
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| M1039-5 | Biovision | each | EUR 796.8 |
TumorExoPure? 0.4 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 10 reactions) |
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| M1032-10 | Biovision | each | EUR 1057.2 |
TumorExoPure? 0.4 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 20 reactions) |
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| M1032-20 | Biovision | each | EUR 1618.8 |
TumorExoPure? 0.4 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 3 reactions) |
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| M1032-3 | Biovision | each | EUR 523.2 |
TumorExoPure? 0.4 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 5 reactions) |
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| M1032-5 | Biovision | each | EUR 796.8 |
TumorExoPure? 1.0 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 10 reactions) |
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| M1033-10 | Biovision | each | EUR 1057.2 |
TumorExoPure? 1.0 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 20 reactions) |
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| M1033-20 | Biovision | each | EUR 1618.8 |
TumorExoPure? 1.0 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 3 reactions) |
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| M1033-3 | Biovision | each | EUR 523.2 |
TumorExoPure? 1.0 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 5 reactions) |
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| M1033-5 | Biovision | each | EUR 796.8 |
MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 10 reactions) |
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| M1034-10 | Biovision | each | EUR 1005.6 |
MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 20 reactions) |
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| M1034-20 | Biovision | each | EUR 1495.2 |
MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 3 reactions) |
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| M1034-3 | Biovision | each | EUR 398.4 |
MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 5 reactions) |
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| M1034-5 | Biovision | each | EUR 777.6 |
MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 10 reactions) |
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| M1035-10 | Biovision | each | EUR 1005.6 |
MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 20 reactions) |
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| M1035-20 | Biovision | each | EUR 1495.2 |
MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 3 reactions) |
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| M1035-3 | Biovision | each | EUR 516 |
MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 5 reactions) |
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| M1035-5 | Biovision | each | EUR 777.6 |
Crohn's Disease Exosome RNA |
|||
| P241-CR | 101Bio | - | Ask for price |
CytoSelect Clonogenic Tumor Cell Isolation Kit (5 preps) |
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| CBA-155 | Cell Biolabs | 5 preps | EUR 957.6 |
|
Description: Many solid tumors contain heterogeneous populations of normal and cancerous cells. Separation of these cell populations is key to an accurate assessment of the true genotypic and phenotypic differences between normal and tumor cells. Our CytoSelect Clonogenic Tumor Cell Isolation Kit uses a proprietary semisolid agar medium to facilitate formation of colonies by cells from solid tumors. Colonies are grown in either a 6-well plate or a 35mm culture dish. These colonies are isolated away from single (i.e. normal) cells by size filtration. The viable cells from these colonies can be easily recovered for further analysis. |
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Lipid Droplet Isolation Kit |
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| MET-5011 | Cell Biolabs | 50 preps | EUR 498 |
|
Description: Lipid droplets are lipid rich organelles found in the adipose tissue of eukaryotes. They function to regulate the hydrolysis and storage of neutral lipids and serve as storage for cholesterol and acyl-glycerols. Lipid droplets have also been associated with inflammatory responses, obesity, atherosclerosis, and cancer. |
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XCF Exosomal DNA Isolation Kit |
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| XCF200A-1 | SBI | 20 rxn | EUR 328 |
CytoSelect Clonogenic Tumor Cell Isolation Kit (5 x 5 preps) |
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| CBA-155-5 | Cell Biolabs | 25 preps | EUR 3894 |
|
Description: Many solid tumors contain heterogeneous populations of normal and cancerous cells. Separation of these cell populations is key to an accurate assessment of the true genotypic and phenotypic differences between normal and tumor cells. Our CytoSelect Clonogenic Tumor Cell Isolation Kit uses a proprietary semisolid agar medium to facilitate formation of colonies by cells from solid tumors. Colonies are grown in either a 6-well plate or a 35mm culture dish. These colonies are isolated away from single (i.e. normal) cells by size filtration. The viable cells from these colonies can be easily recovered for further analysis. |
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ExoPure? Isolation Kit (Cell Media) |
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| K1237-10 | Biovision | each | EUR 796.8 |
ExoPure? Isolation Kit (Cell Media) |
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| K1237-2 | Biovision | each | EUR 470.4 |
ExoPure? Isolation Kit (Stem Cell Media) |
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| K1239-10 | Biovision | each | EUR 901.2 |
ExoPure? Isolation Kit (Stem Cell Media) |
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| K1239-2 | Biovision | each | EUR 510 |
10x Cell Isolation Buffer |
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| 78563 | BPS Bioscience | 5 ml | EUR 25 |
|
Description: This buffer is intended for use with mammalian cells during magnetic cell isolation or single cell processing. This buffer is optimized and formulated to reduce nonspecific binding and cell clumping |
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Apoptotic Cell Isolation Kit |
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| 55R-1349 | Fitzgerald | 30 units | EUR 874.8 |
|
Description: Apoptotic Cell Isolation Kit for use in the research laboratory |
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Apoptotic Cell Isolation Kit |
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| K258-30 | Biovision | each | EUR 561.6 |
Cell Mitochondria Isolation Kit |
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| abx090630-50100tests | Abbexa | 50-100 tests | EUR 309.6 |
CD19 Positive Cell Isolation Kit |
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| 78564-1 | BPS Bioscience | 1 x 10^8 Cells | EUR 70 |
|
Description: The CD19 Positive Cell Isolation Kit is designed to magnetically separate CD19-expressing-cells from a complex immune cell population. This kit is optimized for the isolation of CD19 positive cells from normal human peripheral blood mononuclear cells (PBMCs). Cells are incubated with the antibody:bead complex and placed on a magnet for quick and easy separation. When placed on the magnet, CD19-positive cells will be immobilized along the side of the tube while undesired CD19-negative cells will remain in suspension for easy removal. |
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CD19 Positive Cell Isolation Kit |
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| 78564-2 | BPS Bioscience | 1 x 10^9 Cells | EUR 630 |
|
Description: The CD19 Positive Cell Isolation Kit is designed to magnetically separate CD19-expressing-cells from a complex immune cell population. This kit is optimized for the isolation of CD19 positive cells from normal human peripheral blood mononuclear cells (PBMCs). Cells are incubated with the antibody:bead complex and placed on a magnet for quick and easy separation. When placed on the magnet, CD19-positive cells will be immobilized along the side of the tube while undesired CD19-negative cells will remain in suspension for easy removal. |
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Cell Isolation Magnetic Tube Rack |
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| 78571 | BPS Bioscience | 15 ml and 50 ml | EUR 850 |
|
Description: This Cell Isolation Magnetic Tube Rack is designed to accompany our magnetic cell isolation products, such as the CD19 Positive Cell Isolation Kit (BPS Bioscience #78564). This magnet can quickly separate cells labeled with magnetic beads and is designed to allow users a near 360° view of their cell samples during separation. This magnet can accommodate both 15 and 50 ml tubes simultaneously, which allows flexibility for scaling up or down your isolation samples. Additionally, the rack is compatible with both conical and round-bottom tubes. The compact nature of this magnet allows it to fit easily in various incubators or refrigerators to match desired conditions. |
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Cell Surface Protein Isolation Kit |
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| K295-10 | Biovision | each | EUR 601.2 |
10-min. Single Cell Isolation Kit |
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| P713-20 | 101Bio | - | Ask for price |
MagIso NK Cell Isolation Kit, Human |
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| WHK-B023 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
MagIso CD3 Cell Isolation Kit, Mouse |
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| WHK-B009 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
MagIso CD90.2 Cell Isolation Kit, Mouse |
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| WHK-B010 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
MagIso B Cell (CD43-) Cell Isolation Kit, Human |
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| WHK-B030 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
MagIso CX3CR1 Cell Isolation Kit, Mouse |
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| WHK-B017 | Creative Diagnostics | 10 tests, 100 tests | Ask for price |
Tissue (Tumor) Dissociation / Single Cell Isolation Kit |
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| P712-25 | 101Bio | - | Ask for price |
Tissue (Tumor) Dissociation / Single Cell Isolation Kit |
|||
| P712-4 | 101Bio | - | Ask for price |
Tissue (Tumor) Dissociation / Single Cell Isolation Kit |
|||
| P712-50 | 101Bio | - | Ask for price |
MagIso CD4 T Cell Isolation Kit, Human |
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| WHK-B001 | Creative Diagnostics | 10 tests | EUR 724.8 |
MagIso CD8 T Cell Isolation Kit, Human |
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| WHK-B002 | Creative Diagnostics | 10 tests | EUR 724.8 |
MagIso CD4 T Cell Isolation Kit, Mouse |
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| WHK-B003 | Creative Diagnostics | 10 tests | EUR 724.8 |
MagIso CD8 T Cell Isolation Kit, Mouse |
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| WHK-B004 | Creative Diagnostics | 10 tests | EUR 724.8 |
MagIso Pan B Cell Isolation Kit, Mouse |
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| WHK-B013 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
MagIso Pan B Cell Isolation Kit, Human |
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| WHK-B022 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
Mammalian Cell Genomic DNA Isolation Kit |
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| K967-100 | Biovision | each | EUR 457.2 |
ExoPure? Isolation Kit (Urine) |
|||
| K1240-10 | Biovision | each | EUR 836.4 |
ExoPure? Isolation Kit (Urine) |
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| K1240-2 | Biovision | each | EUR 483.6 |
MagIso Naïve B Cell Isolation Kit, Human |
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| WHK-B024 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
MagIso Neutrophil Cell Isolation Kit, Mouse |
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| WHK-B015 | Creative Diagnostics | 10 tests, 100 tests | Ask for price |
Exo-Urine EV Isolation Kit |
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| EXOU100A-1 | SBI | 2 x 5 reactions | EUR 490 |
MagIso Pan B Cell Isolation Kit, Mouse Ⅱ |
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| WHK-B012 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
FastPure Cell/Tissue DNA Isolation Mini Kit |
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| DC102 | Vazyme | 100 rxn | EUR 212.4 |
FastPure Cell/Tissue DNA Isolation Mini Kit |
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| DC102-01 | Vazyme | 100 rxns | EUR 52 |
FastPure Cell/Tissue Total RNA Isolation Kit |
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| RC101 | Vazyme | 50 rxn | EUR 274.8 |
MagIso Pan Monocyte Cell Isolation Kit, Human |
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| WHK-B021 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
MagIso CD8 Naïve T Cell Isolation Kit, Mouse |
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| WHK-B018 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
MagIso CD4 Naïve T Cell Isolation Kit, Mouse |
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| WHK-B019 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
MagIso CD8 Naïve T Cell Isolation Kit, Human |
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| WHK-B025 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
MagIso CD4 Naïve T Cell Isolation Kit, Human |
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| WHK-B027 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
MagIso Pan Dendritic Cell Isolation Kit, Mouse |
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| WHK-B011 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
ExoPure? Isolation Kit (Bio Fluids) |
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| K1241-10 | Biovision | each | EUR 836.4 |
ExoPure? Isolation Kit (Bio Fluids) |
|||
| K1241-2 | Biovision | each | EUR 483.6 |
MagIso CD8 Memory T Cell Isolation Kit, Human |
|||
| WHK-B026 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
MagIso CD4 Memory T Cell Isolation Kit, Human |
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| WHK-B028 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
MagIso CD14+ Monocytes Cell Isolation Kit, Human |
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| WHK-B029 | Creative Diagnostics | 10 tests, 100 tests | Ask for price |
Rna Isolation Kit |
|||
| 11828665001 | Scientific Laboratory Supplies | EACH | EUR 378.62 |
ExoPure? Isolation Kit (Serum, Plasma) |
|||
| K1238-10 | Biovision | each | EUR 836.4 |
ExoPure? Isolation Kit (Serum, Plasma) |
|||
| K1238-2 | Biovision | each | EUR 470.4 |
FastPure Cell/Tissue Total RNA Isolation Kit V2 |
|||
| RC112-01 | Vazyme | 50 rxns | EUR 82.6 |
miRNA Isolation Kit |
|||
| FAMIK--001 | Favorgen | Rxns: 100 | EUR 398.4 |
|
Description: Contents of the kit:
|
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miRNA Isolation Kit |
|||
| FAMIK--002 | Favorgen | Rxns: 50 | EUR 267.6 |
miRNA Isolation Kit |
|||
| FYG304-100P | Yeastern Biotech | 100 Preps | Ask for price |
EpiQuik Circulating Cell-Free DNA Isolation Kit |
|||
| P-1064 | EpiGentek |
|
|
MagIso Natural killer (NK) Cell Isolation Kit, Mouse |
|||
| WHK-B014 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
MicroRNA Isolation Kit |
|||
| KS341025 | Biochain | 1 kit | EUR 247 |
Endosome Isolation Kit |
|||
| P528 | 101Bio | - | Ask for price |
Microsome Isolation Kit |
|||
| K249-50 | Biovision | each | EUR 633.6 |
Human Whole Blood Polymorphonuclear Cell Isolation Kit |
|||
| K483-30 | Biovision | each | EUR 451.2 |
Hipro Circulating Cell-Free DNA (cfDNA) Isolation Kit |
|||
| W2603-10 | 101Bio | - | Ask for price |