Bone Marrow Mesenchymal Stem Cell Exosomes Promote Brain Microvascular

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Lengthy-chain polyunsaturated omega-Three fatty acids cut back a number of myeloma exosome-mediated suppression of NK cell cytotoxicity

 

Background: Regardless of the advances within the remedy of a number of myeloma (MM), full remission is often difficult. The interactions between tumor and host cells, through which exosomes (EXs) play essential roles, have been proven to be among the many main deteriorative tumor-promoting components herein. Subsequently, any endeavor to beneficially goal these EX-mediated interactions might be of excessive significance.

 

Targets: a) To analyze the results of myeloma EXs on pure killer (NK) cell features. b) To examine whether or not remedy of myeloma cells with eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA), two polyunsaturated omega-Three fatty acids with identified anti-cancer results, can modify myeloma EXs by way of their results on pure killer features.

 

Strategies: L363 cells have been handled with both EPA or DHA or left untreated and the launched EXs (designated as E-EX, D-EX and C-EX, respectively) have been used to deal with NK cells for purposeful research.

 

Outcomes: Myeloma EXs (C-EXs) considerably decreased NK cytotoxicity in opposition to Ok562 cells (P ≤ 0.05), whereas the cytotoxicity suppression was considerably decrease (P ≤ 0.05) within the (E-EX)- and (D-EX)-treated NK cells in comparison with the (C-EX)-treated cells. The expression of the activating NK receptor NKG2D and NK degranulation, after remedy with the EXs, have been each altered following the identical sample. Nevertheless, C-EXs may enhance IFN-γ manufacturing in NK cells (P < 0.01), which was not considerably affected by EPA/DHA remedy. This means a twin impact of myeloma EXs on NK cells features.

 

Conclusion: Our observations confirmed that myeloma EXs have each suppressive and stimulatory results on totally different NK features. Remedy of myeloma cells with EPA/DHA can cut back the suppressive results of myeloma EXs whereas sustaining their stimulatory results. These findings, along with the earlier findings on the anti-cancer results of EPA/DHA, present stronger proof for the repositioning of the presently present EPA/DHA dietary supplements for use within the remedy of MM as an adjuvant remedy.

EXs launched from L363 (myeloma) cells of their regular state enhance IFN-γ manufacturing of NK cells, whereas cut back their cytotoxicity in opposition to the Ok562 cell line (proper blue hint). EXs from L363 cells pre-treated with both EPA or DHA are weaker stimulators of IFN-γ manufacturing.

These EXs additionally enhance NK cytotoxicity and NKG2D expression (left brown hint) in comparison with the EXs obtained from untreated L363 cells. Primarily based on these findings, myeloma EXs have each suppressive and stimulatory results on totally different NK functions relying on the properties of their cells of origin, which will be exploited within the remedy of myeloma.

 

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Exosome Component 9 (EXOSC9) Antibody

abx232908-100ug 100 ug
EUR 661.2

Recombinant Human Exosome Component 9

7-05902 2µg Ask for price

Recombinant Human Exosome Component 9

7-05903 10µg Ask for price

Recombinant Human Exosome Component 9

7-05904 1mg Ask for price

Goat Anti Human Exosome Component 9 (C-Terminal) Polyclonal Antibody

CPBT-67673GH 0.1 mg
EUR 1008

Human Exosome Component 9 (EXOSC9) ELISA Kit

abx387227-96tests 96 tests
EUR 1093.2

EXOSC9 Exosome Component 9 Human Recombinant Protein

PROTQ06265 Regular: 10ug
EUR 380.4
Description: EXOSC9 is a Full-length cDNA coding for the human PM/Scl 75c-beta isoform having a molecular mass of 64 KDa. EXOSC9 protein is fused to a hexa-histidine purification tag.

Exosome Component 8 (EXOSC8) Antibody

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Exosome Component 2 (EXOSC2) Antibody

20-abx003412
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Exosome Component 7 (EXOSC7) Antibody

20-abx124556
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Exosome Component 4 (EXOSC4) Antibody

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Exosome Component 1 (EXOSC1) Antibody

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Exosome Component 2 (EXOSC2) Antibody

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Exosome Component 3 (EXOSC3) Antibody

20-abx125831
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Exosome Component 1 (EXOSC1) Antibody

20-abx112409
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Exosome Component 10 (EXOSC10) Antibody

20-abx112410
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Exosome Component 2 (EXOSC2) Antibody

20-abx112411
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Exosome Component 3 (EXOSC3) Antibody

20-abx112412
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Exosome Component 4 (EXOSC4) Antibody

20-abx112413
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Exosome Component 5 (EXOSC5) Antibody

20-abx112414
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Exosome Component 8 (EXOSC8) Antibody

20-abx112415
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Exosome Component 2 (EXOSC2) Antibody

abx034983-400ul 400 ul
EUR 627.6

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EUR 343.2

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EUR 627.6

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EUR 343.2

Exosome Component 1 (EXOSC1) Antibody

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EUR 627.6

Exosome Component 1 (EXOSC1) Antibody

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EUR 343.2

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20-abx334343
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  • EUR 360.00
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Exosome Component 1 (EXOSC1) Antibody

20-abx301763
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  • EUR 360.00
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Exosome Component 5 (EXOSC5) Antibody

20-abx302857
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  • EUR 360.00
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Exosome Component 8 (EXOSC8) Antibody

20-abx318649
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Exosome Component 3 (EXOSC3) Antibody

20-abx312069
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Exosome Component 1 (EXOSC1) Antibody

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EUR 577.2

Exosome Component 10 (EXOSC10) Antibody

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EUR 661.2

Exosome Component 10 (EXOSC10) Antibody

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EUR 610.8

Exosome Component 2 (EXOSC2) Antibody

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EUR 577.2

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EUR 661.2

Exosome Component 3 (EXOSC3) Antibody

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EUR 577.2

Exosome Component 4 (EXOSC4) Antibody

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EUR 577.2

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EUR 610.8

Exosome Component 7 (EXOSC7) Antibody

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EUR 661.2

Exosome Component 8 (EXOSC8) Antibody

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EUR 577.2

Exosome Component 2 (EXOSC2) Antibody

20-abx172308
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Exosome Component 2 (EXOSC2) Antibody

20-abx176346
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  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
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Exosome Component 3 Protein

20-abx263422
  • EUR 276.00
  • EUR 1930.80
  • EUR 393.60
  • 1 µg
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Exosome Component 1 Protein

20-abx263423
  • EUR 1930.80
  • EUR 393.60
  • EUR 276.00
  • 100 ug
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  • 2 µg

Exosome Component 5 Protein

20-abx260873
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  • 1 mg
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Exosome Component 7 Protein

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Exosome Component 10 Protein

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Exosome Component 4 Protein

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Exosome Component 8 Protein

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  • EUR 276.00
  • 10 ug
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Exosome Component 10 (EXOSC10) Antibody (HRP)

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  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
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Exosome Component 10 (EXOSC10) Antibody (FITC)

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  • EUR 718.80
  • EUR 218.40
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  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 10 (EXOSC10) Antibody (Biotin)

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  • EUR 718.80
  • EUR 218.40
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  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 5 (EXOSC5) Antibody (HRP)

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  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
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Exosome Component 5 (EXOSC5) Antibody (FITC)

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  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 5 (EXOSC5) Antibody (Biotin)

20-abx311413
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  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 3 (EXOSC3) Antibody (HRP)

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  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 3 (EXOSC3) Antibody (FITC)

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  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 3 (EXOSC3) Antibody (Biotin)

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  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 1 (EXOSC1) Antibody (HRP)

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  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
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  • 20 ug
  • 50 ug

Exosome Component 1 (EXOSC1) Antibody (FITC)

20-abx312487
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  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 1 (EXOSC1) Antibody (Biotin)

20-abx312488
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  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 8 (EXOSC8) Antibody (HRP)

20-abx310194
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  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 8 (EXOSC8) Antibody (FITC)

20-abx310195
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  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 8 (EXOSC8) Antibody (Biotin)

20-abx310196
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  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Recombinant Human Exosome Component 10

7-05905 5µg Ask for price

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7-05906 20µg Ask for price

Recombinant Human Exosome Component 10

7-05907 1mg Ask for price

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 418.8

Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human)

4-PAH822Hu01
  • EUR 296.40
  • EUR 3012.00
  • EUR 750.00
  • EUR 372.00
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2)

Human anti exosome complex component RRP45 (EXOSC9) antibody ELISA kit

CSB-EQ027696HU-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human anti exosome complex component RRP45 (EXOSC9) antibody in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human anti exosome complex component RRP45 (EXOSC9) antibody ELISA kit

1-CSB-EQ027696HU
  • EUR 964.80
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  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human anti exosome complex component RRP45 (EXOSC9) antibody in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Exosome Component 2 (EXOSC2) Protein

20-abx653328
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  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
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  • 50 ug

Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), APC

4-PAH822Hu01-APC
  • EUR 414.00
  • EUR 3930.00
  • EUR 1094.40
  • EUR 528.00
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with APC.

Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), Biotinylated

4-PAH822Hu01-Biotin
  • EUR 373.20
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  • EUR 872.40
  • EUR 457.20
  • EUR 262.80
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  • 10ml
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with Biotin.

Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), Cy3

4-PAH822Hu01-Cy3
  • EUR 502.80
  • EUR 5190.00
  • EUR 1410.00
  • EUR 654.00
  • EUR 301.20
  • 100ul
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with Cy3.

Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), FITC

4-PAH822Hu01-FITC
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
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  • 1ml
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with FITC.

Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), HRP

4-PAH822Hu01-HRP
  • EUR 379.20
  • EUR 3426.00
  • EUR 968.40
  • EUR 477.60
  • EUR 247.20
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  • 1ml
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with HRP.

Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), PE

4-PAH822Hu01-PE
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  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
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  • 1ml
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with PE.

Complement Component 9 (C9) Antibody

20-abx171895
  • EUR 978.00
  • EUR 510.00
  • 1 mg
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Complement Component 9 (C9) Antibody

20-abx006787
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  • EUR 218.40
  • EUR 376.80
  • 100 ul
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  • 20 ul
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Complement Component 9 (C9) Antibody

20-abx130005
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  • EUR 159.60
  • EUR 994.80
  • EUR 526.80
  • EUR 326.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Complement Component 9 (C9) Antibody

20-abx128589
  • EUR 360.00
  • EUR 159.60
  • EUR 944.40
  • EUR 493.20
  • EUR 309.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Complement Component 9 (C9) Antibody

20-abx129829
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Complement Component 9 (C9) Antibody

20-abx014387
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Complement Component 9 (C9) Antibody

abx027603-400ul 400 ul
EUR 627.6

Complement Component 9 (C9) Antibody

abx027603-80l 80 µl
EUR 343.2

Complement Component 9 (C9) Antibody

20-abx323893
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Complement Component 9 (C9) Antibody

20-abx312617
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Complement Component 9 (C9) Antibody

abx432434-200ul 200 ul
EUR 460.8

Complement Component 9 (C9) Antibody

20-abx175988
  • EUR 526.80
  • EUR 159.60
  • EUR 1496.40
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Complement Component 9 (C9) Antibody

20-abx175989
  • EUR 526.80
  • EUR 159.60
  • EUR 1513.20
  • EUR 727.20
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Exosome Component 1 (EXOSC1)ELISA Kit

201-12-2688 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Exosome Component 2 (EXOSC2)ELISA Kit

201-12-2689 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Exosome Component 3 (EXOSC3)ELISA Kit

201-12-2690 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Exosome Component 4 (EXOSC4)ELISA Kit

201-12-2691 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Exosome Component 1 (EXOSC5)ELISA Kit

201-12-2692 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Exosome Component 2 (EXOSC2) ELISA Kit

20-abx151457
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Exosome Component 7 (EXOSC7) CLIA Kit

20-abx496063
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Exosome Component 2 (EXOSC2) CLIA Kit

20-abx495555
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Exosome Component 7 (EXOSC7) ELISA Kit

20-abx258177
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Exosome Component 1 (EXOSC1) ELISA Kit

abx387219-96tests 96 tests
EUR 1093.2

Human Exosome Component 10 (EXOSC10) ELISA Kit

abx387220-96tests 96 tests
EUR 1093.2

Human Exosome Component 3 (EXOSC3) ELISA Kit

abx387222-96tests 96 tests
EUR 1093.2

Human Exosome Component 4 (EXOSC4) ELISA Kit

abx387223-96tests 96 tests
EUR 1093.2

Human Exosome Component 5 (EXOSC5) ELISA Kit

abx387224-96tests 96 tests
EUR 1093.2

Human Exosome Component 8 (EXOSC8) ELISA Kit

abx387226-96tests 96 tests
EUR 1093.2

Human Exosome Component 2 (EXOSC2) ELISA Kit

DLR-EXOSC2-Hu-48T 48T
EUR 620.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Exosome Component 2 (EXOSC2) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Exosome Component 2 (EXOSC2) ELISA Kit

DLR-EXOSC2-Hu-96T 96T
EUR 807.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Exosome Component 2 (EXOSC2) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Exosome component 10, EXOSC10 ELISA KIT

ELI-26938h 96 Tests
EUR 988.8

Mouse Exosome component 10, Exosc10 ELISA KIT

ELI-30739m 96 Tests
EUR 1038

EXOSC10Human Exosome Component 10 Human Recombinant Protein

PROTQ01780 Regular: 20ug
EUR 380.4
Description: EXOSC10 Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a molecular mass of 120 kDa. ;EXOSC10 is expressed with a -6xHis tag and purified by proprietary chromatographic techniques.

EXOSC7 Exosome Component 7 Human Recombinant Protein

PROTQ15024 Regular: 20ug
EUR 380.4
Description: EXOSC7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 314 amino acids (1-291 a.a.) and having a molecular mass of 34.2kDa.EXOSC7 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

EXOSC8 Exosome Component 8 Human Recombinant Protein

PROTQ96B26 Regular: 10ug
EUR 380.4
Description: EXOSC8 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 299 amino acids (1-276) and having a molecular mass of 32.4 kDa.;EXOSC8 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

EXOSC4 Exosome Component 4 Human Recombinant Protein

PROTQ9NPD3 Regular: 20ug
EUR 380.4
Description: EXOSC4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 268 amino acids (1-245aa) and having a molecular mass of 28.8kDa.

EXOSC5 Exosome Component 5 Human Recombinant Protein

PROTQ9NQT4 Regular: 25ug
EUR 380.4
Description: EXOSC5 Human Recombinant produced in E. coli is a single polypeptide chain containing 256 amino acids (1-235) and having a molecular mass of 27.5kDa.;EXOSC5 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

EXOSC3 Exosome Component 3 Human Recombinant Protein

PROTQ9NQT5 Regular: 5ug
EUR 380.4
Description: EXOSC3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 298 amino acids (1-275 a.a) and having a molecular mass of 32.0kDa. ;EXOSC3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

EXOSC1 Exosome Component 1 Human Recombinant Protein

PROTQ9Y3B2 Regular: 10ug
EUR 380.4
Description: EXOSC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 218 amino acids (1-195a.a) and having a molecular mass of 23.8kDa. ;EXOSC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Human Exosome Component 2 (EXOSC2) ELISA Kit

SEH822Hu-10x96wellstestplate 10x96-wells test plate
EUR 5677.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 2 (EXOSC2) in Tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 2 (EXOSC2) ELISA Kit

SEH822Hu-1x48wellstestplate 1x48-wells test plate
EUR 572.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 2 (EXOSC2) in Tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 2 (EXOSC2) ELISA Kit

SEH822Hu-1x96wellstestplate 1x96-wells test plate
EUR 766.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 2 (EXOSC2) in Tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 2 (EXOSC2) ELISA Kit

SEH822Hu-5x96wellstestplate 5x96-wells test plate
EUR 3090.6
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 2 (EXOSC2) in Tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 2 (EXOSC2) ELISA Kit

4-SEH822Hu
  • EUR 5738.40
  • EUR 3031.20
  • EUR 768.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Exosome Component 2 (EXOSC2) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Exosome Component 7 (EXOSC7) ELISA Kit

SEM477Hu-10x96wellstestplate 10x96-wells test plate
EUR 6227.58
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 7 (EXOSC7) in Tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 7 (EXOSC7) ELISA Kit

SEM477Hu-1x48wellstestplate 1x48-wells test plate
EUR 618.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 7 (EXOSC7) in Tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 7 (EXOSC7) ELISA Kit

SEM477Hu-1x96wellstestplate 1x96-wells test plate
EUR 831.48
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 7 (EXOSC7) in Tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 7 (EXOSC7) ELISA Kit

SEM477Hu-5x96wellstestplate 5x96-wells test plate
EUR 3381.66
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 7 (EXOSC7) in Tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 7 (EXOSC7) ELISA Kit

4-SEM477Hu
  • EUR 6288.00
  • EUR 3322.80
  • EUR 831.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Exosome Component 7 (EXOSC7) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Exosome Component 2 (EXOSC2) ELISA Kit

RDR-EXOSC2-Hu-48Tests 48 Tests
EUR 652.8

Human Exosome Component 2 (EXOSC2) ELISA Kit

RDR-EXOSC2-Hu-96Tests 96 Tests
EUR 907.2

Human Exosome Component 2 ELISA Kit (EXOSC2)

RK01330 96 Tests
EUR 625.2

Human Exosome Component 7 ELISA Kit (EXOSC7)

RK01331 96 Tests
EUR 625.2

Human Exosome Component 1(EXOSC5)ELISA Kit

QY-E01127 96T
EUR 433.2

Human Exosome Component 4(EXOSC4)ELISA Kit

QY-E01128 96T
EUR 433.2

Human Exosome Component 3(EXOSC3)ELISA Kit

QY-E01129 96T
EUR 433.2

Human Exosome Component 2(EXOSC2)ELISA Kit

QY-E01130 96T
EUR 433.2

Human Exosome Component 1(EXOSC1)ELISA Kit

QY-E01131 96T
EUR 433.2

Human Exosome Component 2 (EXOSC2) ELISA Kit

RD-EXOSC2-Hu-48Tests 48 Tests
EUR 625.2

Human Exosome Component 2 (EXOSC2) ELISA Kit

RD-EXOSC2-Hu-96Tests 96 Tests
EUR 867.6

Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), APC-Cy7

4-PAH822Hu01-APC-Cy7
  • EUR 685.20
  • EUR 7716.00
  • EUR 2046.00
  • EUR 912.00
  • EUR 382.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with APC-Cy7.

Complement Component 9 (C9) Antibody Pair

20-abx370547
  • EUR 1996.80
  • EUR 1279.20
  • 10 × 96 tests
  • 5 × 96 tests

Complement Component 9 (C9) Antibody Pair

20-abx370752
  • EUR 2013.60
  • EUR 1279.20
  • 10 × 96 tests
  • 5 × 96 tests

Complement Component 9 (C9) Antibody (HRP)

20-abx312618
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Complement Component 9 (C9) Antibody (FITC)

20-abx312619
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Complement Component 9 (C9) Antibody (Biotin)

20-abx312620
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Pesticide Mix 9 Containing 16 Compounds in ACN:Acetone (9:1)

SPXPR-9 1ML
EUR 250.8

ELISA kit for Human EXOSC7 (Exosome Component 7)

ELK7511 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Exosome Component 7 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Human EXOSC2 (Exosome Component 2)

ELK4639 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Exosome Component 2 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Bovine Exosome complex component RRP45, EXOSC9 ELISA KIT

ELI-26992b 96 Tests
EUR 1113.6

Bovine Exosome complex component RRP40, EXOSC3 ELISA KIT

ELI-27374b 96 Tests
EUR 1113.6

Human Exosome complex component RRP40, EXOSC3 ELISA KIT

ELI-27375h 96 Tests
EUR 988.8

Mouse Exosome complex component RRP40, Exosc3 ELISA KIT

ELI-27376m 96 Tests
EUR 1038

Bovine Exosome complex component RRP4, EXOSC2 ELISA KIT

ELI-43860b 96 Tests
EUR 1113.6

Mouse Exosome complex component CSL4, Exosc1 ELISA KIT

ELI-47552m 96 Tests
EUR 1038

Mouse Exosome complex component RRP41, Exosc4 ELISA KIT

ELI-32741m 96 Tests
EUR 1038

Mouse Exosome complex component RRP43, Exosc8 ELISA KIT

ELI-32742m 96 Tests
EUR 1038

Human Exosome complex component RRP45, EXOSC9 ELISA KIT

ELI-32743h 96 Tests
EUR 988.8

Human Exosome complex component CSL4, EXOSC1 ELISA KIT

ELI-20569h 96 Tests
EUR 988.8

Bovine Exosome complex component RRP41, EXOSC4 ELISA KIT

ELI-20570b 96 Tests
EUR 1113.6

Human Exosome complex component RRP46, EXOSC5 ELISA KIT

ELI-20571h 96 Tests
EUR 988.8

Mouse Exosome complex component RRP45, Exosc9 ELISA KIT

ELI-20573m 96 Tests
EUR 1038

Mouse Exosome complex component MTR3, Exosc6 ELISA KIT

ELI-30738m 96 Tests
EUR 1038

Human Exosome complex component RRP43, EXOSC8 ELISA KIT

ELI-08330h 96 Tests
EUR 988.8

Human Exosome complex component RRP4, EXOSC2 ELISA KIT

ELI-09275h 96 Tests
EUR 988.8

Bovine Exosome complex component RRP43, EXOSC8 ELISA KIT

ELI-09276b 96 Tests
EUR 1113.6

Human Exosome complex component RRP41, EXOSC4 ELISA KIT

ELI-09561h 96 Tests
EUR 988.8

Mouse Exosome complex component RRP46, Exosc5 ELISA KIT

ELI-09562m 96 Tests
EUR 1038

Human Exosome complex component MTR3, EXOSC6 ELISA KIT

ELI-09563h 96 Tests
EUR 988.8

Mouse Exosome complex component RRP4, Exosc2 ELISA KIT

ELI-09972m 96 Tests
EUR 1038

7095B 9 PASTEUR PIPET

7095B-9 200/pk
EUR 84
Description: Disposable Pipets; Pasteur Pipets

Individual Reaction Mix 9

G065-9 200 reactions
EUR 200.4

Complement Component 9 Protein (OVA)

20-abx165520
  • EUR 744.00
  • EUR 326.40
  • EUR 2230.80
  • EUR 878.40
  • EUR 543.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Recombinant Complement Component 9 (C9)

4-RPB823Hu01
  • EUR 550.08
  • EUR 271.20
  • EUR 1732.80
  • EUR 657.60
  • EUR 1195.20
  • EUR 444.00
  • EUR 4152.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Complement Component 9 expressed in: E.coli

Recombinant Complement Component 9 (C9)

4-RPB823Mu01
  • EUR 593.09
  • EUR 282.00
  • EUR 1894.08
  • EUR 711.36
  • EUR 1302.72
  • EUR 472.80
  • EUR 4555.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Complement Component 9 expressed in: E.coli

Recombinant Complement Component 9 (C9)

4-RPB823Rb01
  • EUR 668.35
  • EUR 302.40
  • EUR 2176.32
  • EUR 805.44
  • EUR 1490.88
  • EUR 523.20
  • EUR 5260.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rabbit Complement Component 9 expressed in: E.coli

9-Component Organic Standard (Brazil)

POR-2914-D 1ML
EUR 111.72

Anti-Complement Component C5b-9 Monoclonal Antibody (aE11) (biotin conjugate)

CTA-013-100ug 100ug Ask for price
Description: Anti-complement component C5b-9 (biotin conjugate) monoclonal antibody (aE11) for ELISA.

Anti-Complement Component C5b-9 Monoclonal Antibody (aE11) (biotin conjugate)

CTA-013-1mg 1mg Ask for price
Description: Anti-complement component C5b-9 (biotin conjugate) monoclonal antibody (aE11) for ELISA.

7095D 9 PASTEUR PIPET BOROSILICATE

7095D-9 200/pk
EUR 93.6
Description: Disposable Pipets; Pasteur Pipets

Complement Component 9 (C9) Polyclonal Antibody (Human)

4-PAB823Hu01
  • EUR 286.80
  • EUR 2869.20
  • EUR 717.60
  • EUR 358.80
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Complement Component 9 (C9)

Complement Component 9 (C9) Polyclonal Antibody (Mouse)

4-PAB823Mu01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Complement Component 9 (C9)

Complement Component 9 (C9) Polyclonal Antibody (Rabbit)

4-PAB823Rb51
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Guinea polyclonal antibody against Rabbit Complement Component 9 (C9)

Human EXOSC7 (Exosome complex component RRP42) ELISA Kit (CUSTOM

ELI-47553h 96 Tests
EUR 988.8

 

 

 

Bone Marrow Mesenchymal Stem Cell Exosomes Promote Mind Microvascular Endothelial Cell Proliferation and Migration in Rats

Goal: To review the impact of bone marrow mesenchyml stem cell (BMSC) exosomes (Exo) on the proliferation and migration of mind microvascular endothelial cells in rats.

 

Strategies: BMSCs have been extracted from rats and recognized. The BMSCs have been co-cultured with bEnd.Three cells in Transwell chamber for 24 h (BMSCs group). Extracted and recognized the BMSCs exosomes (BMSC-Exo). Noticed and qualitatively evaluated the cells’ skills on swallowing the BMSC-Exo below a fluorescence microscope. The optimum work focus of BMSC-Exo was chosen by detecting the cell vitality below totally different BMSC-Exo concentrations by CCK8 methodology. bEnd.Three cells have been co-cultured with BMSC-Exo for 24 h (BMSC-Exo group). bEnd.Three cells cultured alone was set as management group. The proliferation and migration of bEnd.Three cells within the three teams have been respectively detected by EDU and cell scratching experiment after 24 h of tradition.

 

Outcomes: Circulation cytometry confirmed that P3 BMSCs have been CD90 and CD29 constructive and CD45 adverse, with osteogenic differentiation and adipogenesis differentiation, indicating the extracted BMSCs excessive purity. The BMSC-Exo below transmission electron microscopy was round-shaped with a diameter of about 100 nm; NTA evaluation discovered the diameter distribution of BMSC-Exo ranged from 50 to 600 nm, with a peak dimension of 150 nm. Immunofluorescence confirmed that the endothelial cells may swallow BMSC-Exo. CCK8 confirmed that complement of 20 μg/mL BMSC-Exo had the very best impact on cell proliferation.

 

EDU outcomes confirmed that BMSCs group and BMSC-Exo group may promote the proliferation of bEnd.Three cells in contrast with the management group (P<0.05), and there was no distinction between BMSCs group and BMSC-Exo group (P>0.05). Cell scratch take a look at confirmed that the cell mobility of the BMSC-Exo group was larger than that of the management group (P<0.05), however there was no vital distinction between the BMSC-Exo group and the BMSCs group (P>0.05).

 

Conclusion: BMSC-Exo can substitute BMSCs in successfully selling the proliferation and migration of cerebral microvascular endothelial cells, which give a brand new potential remedy for angiogenesis after stroke.

ExoPure? Maxi Chromatography Columns

K1248-3
EUR 1104

ExoPure? Maxi Chromatography Columns

K1248-6
EUR 1690.8

ExoPure? Isolation Kit   (Cell Media)

K1237-10
EUR 796.8

ExoPure? Isolation Kit   (Cell Media)

K1237-2
EUR 470.4

ExoPure? Isolation Kit   (Serum, Plasma)

K1238-10
EUR 836.4

ExoPure? Isolation Kit   (Serum, Plasma)

K1238-2
EUR 470.4

ExoPure? Isolation Kit   (Bio Fluids)

K1241-10
EUR 836.4

ExoPure? Isolation Kit   (Bio Fluids)

K1241-2
EUR 483.6

ExoPure? Reagent (Overall Exosome Isolation, urine)

M1003-25
EUR 992.4

ExoPure? Reagent (Overall Exosome Isolation, urine)

M1003-50
EUR 1083.6

ExoPure? Isolation Kit   (Stem Cell Media)

K1239-10
EUR 901.2

ExoPure? Isolation Kit   (Stem Cell Media)

K1239-2
EUR 510

ExoPure? Reagent (Overall Exosome Isolation, biological fluids)

M1001-10
EUR 796.8

ExoPure? Reagent (Overall Exosome Isolation, biological fluids)

M1001-20
EUR 1260

ExoPure? Reagent (Overall Exosome Isolation, biological fluids)

M1001-5
EUR 633.6

ExoPure? Reagent (Overall Exosome Isolation, cell media)

M1002-25
EUR 992.4

ExoPure? Reagent (Overall Exosome Isolation, cell media)

M1002-50
EUR 1083.6

ExoPure? Immunoplates (Overall Exosome Isolation, serum, colorimetric assay)

M1007-100-T
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, serum, luminometric assay)

M1008-100-W
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, serum, fluorimetric assay)

M1009-100-B
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, colorimetric assay)

M1010-100-T
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, luminometric assay)

M1011-100-W
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, fluorimetric assay)

M1012-100-B
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, colorimetric assay)

M1013-100-T
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, luminometric assay)

M1014-100-W
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, fluorimetric assay)

M1015-100-B
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, plasma, urine, colorimetric assay)

M1004-100-T
EUR 1136.4

ExoPure? Immunoplates (Overall Exosome Isolation, plasma, urine, luminometric assay)

M1005-100-W
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, plasma, urine, fluorometric assay)

M1006-100-B
EUR 888

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum)

M1038-10
EUR 1005.6

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum)

M1038-20
EUR 1546.8

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum)

M1038-3
EUR 523.2

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum)

M1038-5
EUR 796.8

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 10 reactions)

M1030-10
EUR 1005.6

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 20 reactions)

M1030-20
EUR 1546.8

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions)

M1030-3
EUR 529.2

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 5 reactions)

M1030-5
EUR 796.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 10 reactions)

M1031-10
EUR 1005.6

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 20 reactions)

M1031-20
EUR 1546.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions)

M1031-3
EUR 523.2

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 5 reactions)

M1031-5
EUR 796.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 10 reactions)

M1039-10
EUR 1005.6

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 20 reactions)

M1039-20
EUR 1546.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 3 reactions)

M1039-3
EUR 523.2

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 5 reactions)

M1039-5
EUR 796.8

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