Bone Marrow Mesenchymal Stem Cell Exosomes Promote Brain Microvascular

ataxin

Lengthy-chain polyunsaturated omega-Three fatty acids cut back a number of myeloma exosome-mediated suppression of NK cell cytotoxicity

 

Background: Regardless of the advances within the remedy of a number of myeloma (MM), full remission is often difficult. The interactions between tumor and host cells, through which exosomes (EXs) play essential roles, have been proven to be among the many main deteriorative tumor-promoting components herein. Subsequently, any endeavor to beneficially goal these EX-mediated interactions might be of excessive significance.

 

Targets: a) To analyze the results of myeloma EXs on pure killer (NK) cell features. b) To examine whether or not remedy of myeloma cells with eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA), two polyunsaturated omega-Three fatty acids with identified anti-cancer results, can modify myeloma EXs by way of their results on pure killer features.

 

Strategies: L363 cells have been handled with both EPA or DHA or left untreated and the launched EXs (designated as E-EX, D-EX and C-EX, respectively) have been used to deal with NK cells for purposeful research.

 

Outcomes: Myeloma EXs (C-EXs) considerably decreased NK cytotoxicity in opposition to Ok562 cells (P ≤ 0.05), whereas the cytotoxicity suppression was considerably decrease (P ≤ 0.05) within the (E-EX)- and (D-EX)-treated NK cells in comparison with the (C-EX)-treated cells. The expression of the activating NK receptor NKG2D and NK degranulation, after remedy with the EXs, have been each altered following the identical sample. Nevertheless, C-EXs may enhance IFN-γ manufacturing in NK cells (P < 0.01), which was not considerably affected by EPA/DHA remedy. This means a twin impact of myeloma EXs on NK cells features.

 

Conclusion: Our observations confirmed that myeloma EXs have each suppressive and stimulatory results on totally different NK features. Remedy of myeloma cells with EPA/DHA can cut back the suppressive results of myeloma EXs whereas sustaining their stimulatory results. These findings, along with the earlier findings on the anti-cancer results of EPA/DHA, present stronger proof for the repositioning of the presently present EPA/DHA dietary supplements for use within the remedy of MM as an adjuvant remedy.

EXs launched from L363 (myeloma) cells of their regular state enhance IFN-γ manufacturing of NK cells, whereas cut back their cytotoxicity in opposition to the Ok562 cell line (proper blue hint). EXs from L363 cells pre-treated with both EPA or DHA are weaker stimulators of IFN-γ manufacturing.

These EXs additionally enhance NK cytotoxicity and NKG2D expression (left brown hint) in comparison with the EXs obtained from untreated L363 cells. Primarily based on these findings, myeloma EXs have each suppressive and stimulatory results on totally different NK functions relying on the properties of their cells of origin, which will be exploited within the remedy of myeloma.

 

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Exosome Component 9 Peptide
46-967P 0.1 mg
EUR 405.6
Description: (CT) PMSCL1 Peptide

Exosome Component 3 (EXOSC3) Antibody
20-abx312069
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exosome Component 8 (EXOSC8) Antibody
20-abx318649
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  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
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  • 20 ug
  • 50 ug

Exosome Component 1 (EXOSC1) Antibody
abx232898-100ug 100 ug
EUR 577.2

Exosome Component 2 (EXOSC2) Antibody
abx232901-100ug 100 ug
EUR 577.2

Exosome Component 2 (EXOSC2) Antibody
abx232902-100ug 100 ug
EUR 661.2

Exosome Component 3 (EXOSC3) Antibody
abx232903-100ug 100 ug
EUR 577.2

Exosome Component 4 (EXOSC4) Antibody
abx232904-100ug 100 ug
EUR 577.2

Exosome Component 5 (EXOSC5) Antibody
abx232905-100ug 100 ug
EUR 610.8

Exosome Component 7 (EXOSC7) Antibody
abx232906-100ug 100 ug
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Exosome Component 8 (EXOSC8) Antibody
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  • EUR 1446.00
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  • 100 ug
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Exosome Component 2 (EXOSC2) Antibody
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Exosome Component 1 (EXOSC1) Antibody
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  • EUR 372.00
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2)

Human anti exosome complex component RRP45 (EXOSC9) antibody ELISA kit
CSB-EQ027696HU-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human anti exosome complex component RRP45 (EXOSC9) antibody in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

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  • EUR 3244.80
  • 1 plate of 96 wells
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Description: Quantitativesandwich ELISA kit for measuring Human anti exosome complex component RRP45 (EXOSC9) antibody in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), PE
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  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with PE.

Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), APC
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  • EUR 414.00
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  • EUR 1094.40
  • EUR 528.00
  • EUR 262.80
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with APC.

Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), Cy3
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  • EUR 502.80
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with Cy3.

Exosome Component 2 (EXOSC2) Polyclonal Antibody (Human), HRP
4-PAH822Hu01-HRP
  • EUR 379.20
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  • EUR 477.60
  • EUR 247.20
  • 100ul
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with HRP.

Exosome Component 5 Protein
20-abx260873
  • EUR 4101.60
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  • EUR 276.00
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Exosome Component 10 Protein
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  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with FITC.

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PROTQ06265 Regular: 10ug
EUR 380.4
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  • EUR 912.00
  • EUR 382.80
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with APC-Cy7.

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4-PAH822Hu01-Biotin
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  • EUR 872.40
  • EUR 457.20
  • EUR 262.80
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Description: A Rabbit polyclonal antibody against Human Exosome Component 2 (EXOSC2). This antibody is labeled with Biotin.

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7-05906 20µg Ask for price

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20-abx653328
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Human Exosome Component 7 (EXOSC7) CLIA Kit
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  • EUR 5472.00
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  • 10 × 96 tests
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201-12-2688 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

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201-12-2689 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Exosome Component 3 (EXOSC3)ELISA Kit
201-12-2690 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Exosome Component 4 (EXOSC4)ELISA Kit
201-12-2691 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Exosome Component 1 (EXOSC5)ELISA Kit
201-12-2692 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Exosome Component 2 (EXOSC2) ELISA Kit
DLR-EXOSC2-Hu-48T 48T
EUR 620.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Exosome Component 2 (EXOSC2) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Exosome Component 2 (EXOSC2) ELISA Kit
DLR-EXOSC2-Hu-96T 96T
EUR 807.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Exosome Component 2 (EXOSC2) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Exosome Component 7 (EXOSC7) ELISA Kit
SEM477Hu-10x96wellstestplate 10x96-wells test plate
EUR 6227.58
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 7 (EXOSC7) in Tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 7 (EXOSC7) ELISA Kit
SEM477Hu-1x48wellstestplate 1x48-wells test plate
EUR 618.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 7 (EXOSC7) in Tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 7 (EXOSC7) ELISA Kit
SEM477Hu-1x96wellstestplate 1x96-wells test plate
EUR 831.48
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 7 (EXOSC7) in Tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 7 (EXOSC7) ELISA Kit
SEM477Hu-5x96wellstestplate 5x96-wells test plate
EUR 3381.66
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 7 (EXOSC7) in Tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 7 (EXOSC7) ELISA Kit
4-SEM477Hu
  • EUR 6288.00
  • EUR 3322.80
  • EUR 831.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Exosome Component 7 (EXOSC7) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Exosome Component 2 ELISA Kit (EXOSC2)
RK01330 96 Tests
EUR 625.2

Human Exosome Component 7 ELISA Kit (EXOSC7)
RK01331 96 Tests
EUR 625.2

Human Exosome Component 2 (EXOSC2) ELISA Kit
RDR-EXOSC2-Hu-48Tests 48 Tests
EUR 652.8

Human Exosome Component 2 (EXOSC2) ELISA Kit
RDR-EXOSC2-Hu-96Tests 96 Tests
EUR 907.2

Human Exosome Component 1(EXOSC5)ELISA Kit
QY-E01127 96T
EUR 433.2

Human Exosome Component 4(EXOSC4)ELISA Kit
QY-E01128 96T
EUR 433.2

Human Exosome Component 3(EXOSC3)ELISA Kit
QY-E01129 96T
EUR 433.2

Human Exosome Component 2(EXOSC2)ELISA Kit
QY-E01130 96T
EUR 433.2

Human Exosome Component 1(EXOSC1)ELISA Kit
QY-E01131 96T
EUR 433.2

Human Exosome Component 2 (EXOSC2) ELISA Kit
RD-EXOSC2-Hu-48Tests 48 Tests
EUR 625.2

Human Exosome Component 2 (EXOSC2) ELISA Kit
RD-EXOSC2-Hu-96Tests 96 Tests
EUR 867.6

Human Exosome Component 2 (EXOSC2) ELISA Kit
SEH822Hu-10x96wellstestplate 10x96-wells test plate
EUR 5677.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 2 (EXOSC2) in Tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 2 (EXOSC2) ELISA Kit
SEH822Hu-1x48wellstestplate 1x48-wells test plate
EUR 572.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 2 (EXOSC2) in Tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 2 (EXOSC2) ELISA Kit
SEH822Hu-1x96wellstestplate 1x96-wells test plate
EUR 766.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 2 (EXOSC2) in Tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 2 (EXOSC2) ELISA Kit
SEH822Hu-5x96wellstestplate 5x96-wells test plate
EUR 3090.6
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Exosome Component 2 (EXOSC2) in Tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 2 (EXOSC2) ELISA Kit
4-SEH822Hu
  • EUR 5738.40
  • EUR 3031.20
  • EUR 768.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Exosome Component 2 (EXOSC2) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Exosome Component 2 (EXOSC2) ELISA Kit
RD-EXOSC2-Hu-48T 48T
EUR 452.7
Description: tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 2 (EXOSC2) ELISA Kit
RD-EXOSC2-Hu-96T 96T
EUR 646.7
Description: tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 1 (EXOSC1)ELISA Kit
YLA3328HU-48T 48T
EUR 435

Human Exosome Component 1 (EXOSC1)ELISA Kit
YLA3328HU-96T 96T
EUR 562.5

Human Exosome Component 2 (EXOSC2)ELISA Kit
YLA3329HU-48T 48T
EUR 435

Human Exosome Component 2 (EXOSC2)ELISA Kit
YLA3329HU-96T 96T
EUR 562.5

Human Exosome Component 3 (EXOSC3)ELISA Kit
YLA3330HU-48T 48T
EUR 435

Human Exosome Component 3 (EXOSC3)ELISA Kit
YLA3330HU-96T 96T
EUR 562.5

Human Exosome Component 4 (EXOSC4)ELISA Kit
YLA3331HU-48T 48T
EUR 435

Human Exosome Component 4 (EXOSC4)ELISA Kit
YLA3331HU-96T 96T
EUR 562.5

Human Exosome Component 1 (EXOSC5)ELISA Kit
YLA3332HU-48T 48T
EUR 435

Human Exosome Component 1 (EXOSC5)ELISA Kit
YLA3332HU-96T 96T
EUR 562.5

Human Exosome Component 2 (EXOSC2) ELISA Kit
RDR-EXOSC2-Hu-48T 48T
EUR 475.34
Description: tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 2 (EXOSC2) ELISA Kit
RDR-EXOSC2-Hu-96T 96T
EUR 679.04
Description: tissue homogenates, cell lysates and other biological fluids.

Human Exosome Component 10 (EXOSC10) ELISA Kit
abx387220-96tests 96 tests
EUR 1093.2

Human Exosome component 10, EXOSC10 ELISA KIT
ELI-26938h 96 Tests
EUR 988.8

Mouse Exosome component 10, Exosc10 ELISA KIT
ELI-30739m 96 Tests
EUR 1038

ELISA kit for Human EXOSC2 (Exosome Component 2)
ELK4639 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Exosome Component 2 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Human EXOSC7 (Exosome Component 7)
ELK7511 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Exosome Component 7 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Mouse Exosome complex component CSL4, Exosc1 ELISA KIT
ELI-47552m 96 Tests
EUR 1038

Human Exosome complex component RRP4, EXOSC2 ELISA KIT
ELI-09275h 96 Tests
EUR 988.8

Human Exosome complex component MTR3, EXOSC6 ELISA KIT
ELI-09563h 96 Tests
EUR 988.8

Mouse Exosome complex component MTR3, Exosc6 ELISA KIT
ELI-30738m 96 Tests
EUR 1038

Human Exosome complex component CSL4, EXOSC1 ELISA KIT
ELI-20569h 96 Tests
EUR 988.8

Mouse Exosome complex component RRP4, Exosc2 ELISA KIT
ELI-09972m 96 Tests
EUR 1038

EXOSC8 Exosome Component 8 Human Recombinant Protein
PROTQ96B26 Regular: 10ug
EUR 380.4
Description: EXOSC8 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 299 amino acids (1-276) and having a molecular mass of 32.4 kDa.;EXOSC8 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

EXOSC4 Exosome Component 4 Human Recombinant Protein
PROTQ9NPD3 Regular: 20ug
EUR 380.4
Description: EXOSC4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 268 amino acids (1-245aa) and having a molecular mass of 28.8kDa.

EXOSC5 Exosome Component 5 Human Recombinant Protein
PROTQ9NQT4 Regular: 25ug
EUR 380.4
Description: EXOSC5 Human Recombinant produced in E. coli is a single polypeptide chain containing 256 amino acids (1-235) and having a molecular mass of 27.5kDa.;EXOSC5 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

EXOSC3 Exosome Component 3 Human Recombinant Protein
PROTQ9NQT5 Regular: 5ug
EUR 380.4
Description: EXOSC3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 298 amino acids (1-275 a.a) and having a molecular mass of 32.0kDa. ;EXOSC3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

EXOSC1 Exosome Component 1 Human Recombinant Protein
PROTQ9Y3B2 Regular: 10ug
EUR 380.4
Description: EXOSC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 218 amino acids (1-195a.a) and having a molecular mass of 23.8kDa. ;EXOSC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

EXOSC7 Exosome Component 7 Human Recombinant Protein
PROTQ15024 Regular: 20ug
EUR 380.4
Description: EXOSC7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 314 amino acids (1-291 a.a.) and having a molecular mass of 34.2kDa.EXOSC7 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Human Exosome complex component RRP43, EXOSC8 ELISA KIT
ELI-08330h 96 Tests
EUR 988.8

Human Exosome complex component RRP41, EXOSC4 ELISA KIT
ELI-09561h 96 Tests
EUR 988.8

Mouse Exosome complex component RRP46, Exosc5 ELISA KIT
ELI-09562m 96 Tests
EUR 1038

Human Exosome complex component RRP40, EXOSC3 ELISA KIT
ELI-27375h 96 Tests
EUR 988.8

Mouse Exosome complex component RRP40, Exosc3 ELISA KIT
ELI-27376m 96 Tests
EUR 1038

Mouse Exosome complex component RRP41, Exosc4 ELISA KIT
ELI-32741m 96 Tests
EUR 1038

Mouse Exosome complex component RRP43, Exosc8 ELISA KIT
ELI-32742m 96 Tests
EUR 1038

Human Exosome complex component RRP45, EXOSC9 ELISA KIT
ELI-32743h 96 Tests
EUR 988.8

Bovine Exosome complex component RRP4, EXOSC2 ELISA KIT
ELI-43860b 96 Tests
EUR 1113.6

Human Exosome complex component RRP46, EXOSC5 ELISA KIT
ELI-20571h 96 Tests
EUR 988.8

Mouse Exosome complex component RRP45, Exosc9 ELISA KIT
ELI-20573m 96 Tests
EUR 1038

Bovine Exosome complex component RRP43, EXOSC8 ELISA KIT
ELI-09276b 96 Tests
EUR 1113.6

Bovine Exosome complex component RRP45, EXOSC9 ELISA KIT
ELI-26992b 96 Tests
EUR 1113.6

Bovine Exosome complex component RRP40, EXOSC3 ELISA KIT
ELI-27374b 96 Tests
EUR 1113.6

Bovine Exosome complex component RRP41, EXOSC4 ELISA KIT
ELI-20570b 96 Tests
EUR 1113.6

EXOSC10Human Exosome Component 10 Human Recombinant Protein
PROTQ01780 Regular: 20ug
EUR 380.4
Description: EXOSC10 Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a molecular mass of 120 kDa. ;EXOSC10 is expressed with a -6xHis tag and purified by proprietary chromatographic techniques.

Human EXOSC7 (Exosome complex component RRP42) ELISA Kit (CUSTOM
ELI-47553h 96 Tests
EUR 988.8

Mouse EXOSC7 (Exosome complex component RRP42) ELISA Kit (CUSTOM
ELI-20572m 96 Tests
EUR 1038

Complement Component 9 (C9) Antibody
20-abx312617
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Complement Component 9 (C9) Antibody
20-abx175988
  • EUR 526.80
  • EUR 159.60
  • EUR 1496.40
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Complement Component 9 (C9) Antibody
20-abx175989
  • EUR 526.80
  • EUR 159.60
  • EUR 1513.20
  • EUR 727.20
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Complement Component 9 (C9) Antibody
20-abx171895
  • EUR 978.00
  • EUR 510.00
  • 1 mg
  • 200 ug

Complement Component 9 (C9) Antibody
abx027603-400ul 400 ul
EUR 627.6

Complement Component 9 (C9) Antibody
abx027603-80l 80 µl
EUR 343.2

Complement Component 9 (C9) Antibody
20-abx128589
  • EUR 360.00
  • EUR 159.60
  • EUR 944.40
  • EUR 493.20
  • EUR 309.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Complement Component 9 (C9) Antibody
20-abx129829
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Complement Component 9 (C9) Antibody
20-abx130005
  • EUR 376.80
  • EUR 159.60
  • EUR 994.80
  • EUR 526.80
  • EUR 326.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Complement Component 9 (C9) Antibody
20-abx323893
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Complement Component 9 (C9) Antibody
abx432434-200ul 200 ul
EUR 460.8

Complement Component 9 (C9) Antibody
20-abx006787
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Complement Component 9 (C9) Antibody
20-abx014387
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Complement Component 9 (C9) Antibody (HRP)
20-abx312618
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Complement Component 9 (C9) Antibody (FITC)
20-abx312619
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Complement Component 9 (C9) Antibody Pair
20-abx370547
  • EUR 1996.80
  • EUR 1279.20
  • 10 × 96 tests
  • 5 × 96 tests

 

 

 

Bone Marrow Mesenchymal Stem Cell Exosomes Promote Mind Microvascular Endothelial Cell Proliferation and Migration in Rats

Goal: To review the impact of bone marrow mesenchyml stem cell (BMSC) exosomes (Exo) on the proliferation and migration of mind microvascular endothelial cells in rats.

 

Strategies: BMSCs have been extracted from rats and recognized. The BMSCs have been co-cultured with bEnd.Three cells in Transwell chamber for 24 h (BMSCs group). Extracted and recognized the BMSCs exosomes (BMSC-Exo). Noticed and qualitatively evaluated the cells’ skills on swallowing the BMSC-Exo below a fluorescence microscope. The optimum work focus of BMSC-Exo was chosen by detecting the cell vitality below totally different BMSC-Exo concentrations by CCK8 methodology. bEnd.Three cells have been co-cultured with BMSC-Exo for 24 h (BMSC-Exo group). bEnd.Three cells cultured alone was set as management group. The proliferation and migration of bEnd.Three cells within the three teams have been respectively detected by EDU and cell scratching experiment after 24 h of tradition.

 

Outcomes: Circulation cytometry confirmed that P3 BMSCs have been CD90 and CD29 constructive and CD45 adverse, with osteogenic differentiation and adipogenesis differentiation, indicating the extracted BMSCs excessive purity. The BMSC-Exo below transmission electron microscopy was round-shaped with a diameter of about 100 nm; NTA evaluation discovered the diameter distribution of BMSC-Exo ranged from 50 to 600 nm, with a peak dimension of 150 nm. Immunofluorescence confirmed that the endothelial cells may swallow BMSC-Exo. CCK8 confirmed that complement of 20 μg/mL BMSC-Exo had the very best impact on cell proliferation.

 

EDU outcomes confirmed that BMSCs group and BMSC-Exo group may promote the proliferation of bEnd.Three cells in contrast with the management group (P<0.05), and there was no distinction between BMSCs group and BMSC-Exo group (P>0.05). Cell scratch take a look at confirmed that the cell mobility of the BMSC-Exo group was larger than that of the management group (P<0.05), however there was no vital distinction between the BMSC-Exo group and the BMSCs group (P>0.05).

 

Conclusion: BMSC-Exo can substitute BMSCs in successfully selling the proliferation and migration of cerebral microvascular endothelial cells, which give a brand new potential remedy for angiogenesis after stroke.

ExoPure? Maxi Chromatography Columns
K1248-3 each
EUR 1104

ExoPure? Maxi Chromatography Columns
K1248-6 each
EUR 1690.8

ExoPure? Isolation Kit   (Cell Media)
K1237-10 each
EUR 796.8

ExoPure? Isolation Kit   (Cell Media)
K1237-2 each
EUR 470.4

ExoPure? Isolation Kit   (Bio Fluids)
K1241-10 each
EUR 836.4

ExoPure? Isolation Kit   (Bio Fluids)
K1241-2 each
EUR 483.6

ExoPure? Isolation Kit   (Serum, Plasma)
K1238-10 each
EUR 836.4

ExoPure? Isolation Kit   (Serum, Plasma)
K1238-2 each
EUR 470.4

ExoPure? Isolation Kit   (Stem Cell Media)
K1239-10 each
EUR 901.2

ExoPure? Isolation Kit   (Stem Cell Media)
K1239-2 each
EUR 510

ExoPure? Reagent (Overall Exosome Isolation, urine)
M1003-25 each
EUR 992.4

ExoPure? Reagent (Overall Exosome Isolation, urine)
M1003-50 each
EUR 1083.6

ExoPure? Reagent (Overall Exosome Isolation, cell media)
M1002-25 each
EUR 992.4

ExoPure? Reagent (Overall Exosome Isolation, cell media)
M1002-50 each
EUR 1083.6

ExoPure? Reagent (Overall Exosome Isolation, biological fluids)
M1001-10 each
EUR 796.8

ExoPure? Reagent (Overall Exosome Isolation, biological fluids)
M1001-20 each
EUR 1260

ExoPure? Reagent (Overall Exosome Isolation, biological fluids)
M1001-5 each
EUR 633.6

ExoPure? Immunoplates (Overall Exosome Isolation, serum, colorimetric assay)
M1007-100-T each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, serum, luminometric assay)
M1008-100-W each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, serum, fluorimetric assay)
M1009-100-B each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, colorimetric assay)
M1010-100-T each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, luminometric assay)
M1011-100-W each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, fluorimetric assay)
M1012-100-B each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, colorimetric assay)
M1013-100-T each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, luminometric assay)
M1014-100-W each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, saliva, fluorimetric assay)
M1015-100-B each
EUR 888

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum)
M1038-10 each
EUR 1005.6

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum)
M1038-20 each
EUR 1546.8

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum)
M1038-3 each
EUR 523.2

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum)
M1038-5 each
EUR 796.8

ExoPure? Immunoplates (Overall Exosome Isolation, plasma, urine, colorimetric assay)
M1004-100-T each
EUR 1136.4

ExoPure? Immunoplates (Overall Exosome Isolation, plasma, urine, luminometric assay)
M1005-100-W each
EUR 888

ExoPure? Immunoplates (Overall Exosome Isolation, plasma, urine, fluorometric assay)
M1006-100-B each
EUR 888

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 10 reactions)
M1030-10 each
EUR 1005.6

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 20 reactions)
M1030-20 each
EUR 1546.8

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions)
M1030-3 each
EUR 529.2

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 5 reactions)
M1030-5 each
EUR 796.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 10 reactions)
M1031-10 each
EUR 1005.6

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 20 reactions)
M1031-20 each
EUR 1546.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions)
M1031-3 each
EUR 523.2

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 5 reactions)
M1031-5 each
EUR 796.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 10 reactions)
M1039-10 each
EUR 1005.6

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 20 reactions)
M1039-20 each
EUR 1546.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 3 reactions)
M1039-3 each
EUR 523.2

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 5 reactions)
M1039-5 each
EUR 796.8

Illustra Exoprostar 100 RCN
US78210 EACH
EUR 87.6

Illustra Exoprostar 500 RCN
US78211 EACH
EUR 334.8

Illustra Exoprostar 2000 RCN
US78212 EACH
EUR 1197.6

Exophilin 5 (EXPH5) Antibody
20-abx313705
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exophilin 5 (EXPH5) Antibody
abx232909-100ug 100 ug
EUR 661.2

Exophilin 5 (EXPH5) Antibody (HRP)
20-abx313706
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mouse Exophilin 5 (EXPH5) ELISA Kit
abx389223-96tests 96 tests
EUR 1093.2

Human Exophilin 5 (EXPH5) ELISA Kit
abx387228-96tests 96 tests
EUR 1093.2

Human Exophilin 5 (EXPH5)ELISA Kit
201-12-2684 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Exophilin- 5, EXPH5 ELISA KIT
ELI-47267h 96 Tests
EUR 988.8

Mouse Exophilin- 5, Exph5 ELISA KIT
ELI-26993m 96 Tests
EUR 1038

Human Exophilin 5(EXPH5)ELISA Kit
QY-E04934 96T
EUR 433.2

Illustra ExoPro S 100 Reactions
US79010 EACH
EUR 80.4

Human Exophilin 5 (EXPH5)ELISA Kit
YLA3324HU-48T 48T
EUR 435

Human Exophilin 5 (EXPH5)ELISA Kit
YLA3324HU-96T 96T
EUR 562.5

Exophilin 5 (EXPH5) Antibody (FITC)
20-abx313707
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exophilin 5 (EXPH5) Antibody (Biotin)
20-abx313708
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exph5 ELISA Kit| Mouse Exophilin-5 ELISA Kit
EF014853 96 Tests
EUR 826.8

Exopolyphosphatase (PPX1) Antibody
20-abx300871
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exopolyphosphatase (PPX1) Antibody (HRP)
20-abx300912
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Exopolyphosphatase (PPX1) Antibody (FITC)
20-abx300913
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Escherichia coli O6:H1 Exopolyphosphatase (ppx)
1-CSB-EP360285EGX
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Escherichia coli O6:H1 Exopolyphosphatase(ppx) expressed in E.coli

Escherichia coli Exopolyphosphatase (ppx)
1-CSB-EP365319ENV
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Escherichia coli Exopolyphosphatase(ppx) expressed in E.coli

Escherichia coli O6:H1 Exopolyphosphatase (ppx)
1-CSB-YP360285EGX
  • EUR 814.80
  • EUR 402.00
  • EUR 2606.40
  • EUR 1261.20
  • EUR 1730.40
  • EUR 522.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Escherichia coli O6:H1 Exopolyphosphatase(ppx) expressed in Yeast

Exopolyphosphatase (PPX1) Antibody (Biotin)
20-abx300914
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Prune Exopolyphosphatase 1 (PRUNE1) Antibody
20-abx334087
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Prune Exopolyphosphatase 1 (PRUNE1) Antibody (HRP)
20-abx337306
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Prune Exopolyphosphatase 1 (PRUNE1) Antibody (FITC)
20-abx337307
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Prune Exopolyphosphatase 1 (PRUNE1) Antibody (Biotin)
20-abx337308
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Saccharomyces cerevisiae Exopolyphosphatase (PPX1)
1-CSB-EP334459SVG
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Saccharomyces cerevisiae Exopolyphosphatase(PPX1) expressed in E.coli

Saccharomyces cerevisiae Exopolyphosphatase (PPX1)
1-CSB-YP334459SVG
  • EUR 814.80
  • EUR 402.00
  • EUR 2606.40
  • EUR 1261.20
  • EUR 1730.40
  • EUR 522.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Saccharomyces cerevisiae Exopolyphosphatase(PPX1) expressed in Yeast

Recombinant E.coli Exopolyphosphatase Protein, His-SUMO, E.coli-10ug
QP7336-ec-10ug 10ug
EUR 391.2

Recombinant E.coli Exopolyphosphatase Protein, His-SUMO, E.coli-1mg
QP7336-ec-1mg 1mg
EUR 2763.6

Recombinant E.coli Exopolyphosphatase Protein, His-SUMO, E.coli-50ug
QP7336-ec-50ug 50ug
EUR 522

Recombinant S. cerevisiae Exopolyphosphatase Protein, His, E.coli-10ug
QP7169-ec-10ug 10ug
EUR 391.2

Recombinant S. cerevisiae Exopolyphosphatase Protein, His, E.coli-1mg
QP7169-ec-1mg 1mg
EUR 2763.6

Recombinant S. cerevisiae Exopolyphosphatase Protein, His, E.coli-50ug
QP7169-ec-50ug 50ug
EUR 522

Recombinant E.coli Exopolyphosphatase Protein, His-SUMO, E.coli-100ug
QP7336-ec-100ug 100ug
EUR 848.4

Recombinant E.coli Exopolyphosphatase Protein, His-SUMO, E.coli-200ug
QP7336-ec-200ug 200ug
EUR 1338

Recombinant E.coli Exopolyphosphatase Protein, His-SUMO, E.coli-500ug
QP7336-ec-500ug 500ug
EUR 1816.8

Recombinant S. cerevisiae Exopolyphosphatase Protein, His, E.coli-100ug
QP7169-ec-100ug 100ug
EUR 848.4

Recombinant S. cerevisiae Exopolyphosphatase Protein, His, E.coli-200ug
QP7169-ec-200ug 200ug
EUR 1338

Recombinant S. cerevisiae Exopolyphosphatase Protein, His, E.coli-500ug
QP7169-ec-500ug 500ug
EUR 1816.8

Exo70 (Exo70) Antibody
abx232892-100ug 100 ug
EUR 577.2

Exo I 10 U Ul 5000 Units
E70073X EACH
EUR 672

Exo70 Antibody
DF12988 200ul
EUR 420

Exo70 ELISA KIT|Human
EF009471 96 Tests
EUR 826.8

anti- Exo70 antibody
FNab02892 100µg
EUR 606.3
Description: Antibody raised against Exo70

Exonuclease V / EXO5 / DEM1
F54546-0.08ML 0.08 ml
EUR 140.25
Description: Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair. [UniProt]

Exonuclease V / EXO5 / DEM1
F54546-0.4ML 0.4 ml
EUR 322.15
Description: Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair. [UniProt]

Exo70 Blocking Peptide
DF12988-BP 1mg
EUR 234

Human Exonuclease V (EXO5)
1-CSB-EP863995HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Exonuclease V(EXO5) expressed in E.coli

Exo1
B6876-10 10 mg
EUR 150
Description: IC50: about 20 ?M for exocytosisExo1 is a chemical inhibitor of the exocytic pathway.

Exo1
B6876-100 100 mg
EUR 619.2
Description: IC50: about 20 ?M for exocytosisExo1 is a chemical inhibitor of the exocytic pathway.

Exo1
B6876-5.1 10 mM (in 1mL DMSO)
EUR 158.4
Description: IC50: about 20 ?M for exocytosisExo1 is a chemical inhibitor of the exocytic pathway.

Exo1
B6876-50 50 mg
EUR 385.2
Description: IC50: about 20 ?M for exocytosisExo1 is a chemical inhibitor of the exocytic pathway.

Exo1
HY-112670 50mg
EUR 308.4

Tau Peptide (45-73) (Exon 2/Insert 1 Domain)
H-7804.1000 1.0mg
EUR 205.2
Description: Sum Formula: C120H189N31O57; CAS# [2022956-54-1] net

Tau Peptide (74-102) (Exon 3/Insert 2 Domain)
H-7806.0500 0.5mg
EUR 135.6
Description: Sum Formula: C124H198N34O46; CAS# [1322695-34-0] net

Tau Peptide (74-102) (Exon 3/Insert 2 Domain)
H-7806.1000 1.0mg
EUR 205.2
Description: Sum Formula: C124H198N34O46; CAS# [1322695-34-0] net

Tau Peptide (45-73) (Exon 2/Insert 1 Domain)
H-7804.0500 0.5mg
EUR 135.6
Description: Sum Formula: C120H189N31O57; CAS# [2022956-54-1] net

Exonuclease 1 (EXO1) Antibody
abx232891-100ug 100 ug
EUR 661.2

Rat Exonuclease 1 (EXO1) Protein
20-abx168983
  • EUR 844.80
  • EUR 343.20
  • EUR 2581.20
  • EUR 994.80
  • EUR </